Schizophrenia: Positive and Negative Symptoms

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Questions and Answers

Which of the following is an example of a positive symptom of schizophrenia?

  • Asociality
  • Avolition
  • Hallucinations (correct)
  • Alogia

A patient experiencing poverty of speech is exhibiting which type of symptom associated with schizophrenia?

  • Affective
  • Cognitive
  • Positive
  • Negative (correct)

What distinguishes negative symptoms of schizophrenia from positive symptoms?

  • Negative symptoms involve a reduction or absence of normal functions. (correct)
  • Negative symptoms only appear during the active phase of schizophrenia.
  • Negative symptoms are easier to treat with medication.
  • Negative symptoms involve an excess or distortion of normal functions.

Which of the following is considered one of the 'five A's' of negative symptoms in schizophrenia?

<p>Anhedonia (B)</p> Signup and view all the answers

A patient who has a flat facial expression and speaks in a monotone voice is most likely exhibiting which negative symptom of schizophrenia?

<p>Affective Blunting (A)</p> Signup and view all the answers

Lack of motivation for action is referred to as what in the context of negative symptoms of schizophrenia?

<p>Avolition (C)</p> Signup and view all the answers

Which of schizophrenia's phases is characterized by a decline in interest in usual activities and withdrawal from social interactions?

<p>Prodromal Phase (D)</p> Signup and view all the answers

During which phase of schizophrenia do both positive and negative symptoms typically manifest?

<p>Active Phase (B)</p> Signup and view all the answers

A patient is currently experiencing listlessness and difficulty concentrating after a period of hallucinations and delusions. Which phase of schizophrenia is the patient most likely in?

<p>Residual Phase (C)</p> Signup and view all the answers

Which of the following best describes the 'kindling' phenomenon in the context of schizophrenia?

<p>The gradual worsening of symptoms after each active phase. (A)</p> Signup and view all the answers

According to the diagnostic criteria for schizophrenia, how long must disturbances in functioning be present to meet requirement?

<p>At least 6 months (A)</p> Signup and view all the answers

Schizophreniform disorder differs from schizophrenia primarily in:

<p>The duration of symptoms. (B)</p> Signup and view all the answers

What is a key diagnostic criterion that differentiates schizoaffective disorder from schizophrenia?

<p>Presence of delusions or hallucinations for at least 2 weeks in the absence of prominent mood symptoms. (A)</p> Signup and view all the answers

Why is early treatment of schizophrenia considered crucial?

<p>To improve long-term outcomes and potentially preserve brain tissue. (A)</p> Signup and view all the answers

What is the primary mechanism of action (MOA) of first-generation antipsychotics (FGAs) in treating schizophrenia?

<p>Blocking dopamine D2 receptors (C)</p> Signup and view all the answers

Second-generation antipsychotics (SGAs) are often preferred over first-generation antipsychotics (FGAs) due to:

<p>A lower risk of extrapyramidal symptoms. (D)</p> Signup and view all the answers

What is the significance of 5-HT2A antagonism in the mechanism of action of some second-generation antipsychotics (SGAs)?

<p>Specifically improves negative symptoms and improves cognition (C)</p> Signup and view all the answers

According to the information, which medication is generally NOT recommended as a first-line antipsychotic due to its association with significant weight gain?

<p>Olanzapine (C)</p> Signup and view all the answers

What is a notable side effect associated with Risperidone compared to other second-generation antipsychotics?

<p>Low sedation (B)</p> Signup and view all the answers

What is a potential ocular side effect associated with quetiapine (Seroquel)?

<p>Increased risk of cataracts (A)</p> Signup and view all the answers

Clozapine is often reserved as a third trial drug because of what potentially dangerous side effect?

<p>Agranulocytosis (D)</p> Signup and view all the answers

What monitoring is required with Clozapine?

<p>Absolute Neutrophil Count (C)</p> Signup and view all the answers

Ziprasidone is especially used in which setting?

<p>In injection form for acute psychosis in the ER (D)</p> Signup and view all the answers

What is a key advantage of using long-acting injectable antipsychotics (LAIs) in the treatment of schizophrenia?

<p>Improved medication compliance. (B)</p> Signup and view all the answers

What is post-injection delirium/sedation syndrome, a serious adverse effect sometimes associated with?

<p>Olanzapine Pamoate (A)</p> Signup and view all the answers

A patient with schizophrenia is struggling to adhere to their oral medication regimen. Which of the following antipsychotics has a long-acting injectable (LAI) formulation that requires oral supplementation for a few weeks?

<p>Aripiprazole monohydrate (C)</p> Signup and view all the answers

Which medication is considered relatively safe for pregnant women?

<p>Haloperidol (D)</p> Signup and view all the answers

What is Cognitive Behavioral Therapy in managing Schizophrenia?

<p>Challenging reality (C)</p> Signup and view all the answers

A patient with treatment-resistant schizophrenia (TRS) has failed trials of multiple antipsychotics. What is the next step?

<p>Initiating a trial of clozapine (A)</p> Signup and view all the answers

In Treatment-resistant schizophrenia, what are we reviewing history for?

<p>atypical features? neurological symptoms? toxin exposures? (D)</p> Signup and view all the answers

A patient who smokes and requires higher dose because of it, would also get an increased level of clozapine through?

<p>Caffeine (D)</p> Signup and view all the answers

According to the information provided, what is a common sign of Acute Dystonia?

<p>Sustained painful muscle contractions (A)</p> Signup and view all the answers

What is a drug used for treatment in patients with Acute Dystonia?

<p>Baclofen (muscle relaxant) (B)</p> Signup and view all the answers

Fidgeting legs, rocking from side to side is a sign of what?

<p>Akathisia (B)</p> Signup and view all the answers

“Pill rolling tremor” is a sign of what?

<p>Parkinsonism (A)</p> Signup and view all the answers

According to the material, what symptoms would a patient with Tardive dyskinesia may face?

<p>Facial grimacing (A)</p> Signup and view all the answers

A patient who is stiff, hot and out of it would be suffering from which condition?

<p>Neuroleptic Malignant Syndrome (D)</p> Signup and view all the answers

While a patient has Serotonin Syndrome, what are you most likely going to see in a patient’s reflexes?

<p>Increased (B)</p> Signup and view all the answers

Which is a symptom that is present in Neuroleptic Malignant Syndrome?

<p>Muscle Rigidity (B)</p> Signup and view all the answers

What would you prescribe to treat patients with Neuroleptic Malignant Syndrome?

<p>Dantrolene (D)</p> Signup and view all the answers

Medications for Schizophrenia require the patient to take everyday for how long to then consider re-assessing?

<p>1 year (B)</p> Signup and view all the answers

What is the rationale behind obtaining pretreatment labs and indices when initiating antipsychotic medication?

<p>To establish a baseline for monitoring potential metabolic and cardiovascular side effects. (D)</p> Signup and view all the answers

What is the primary mechanism by which first-generation antipsychotics (FGAs) exert their therapeutic effect?

<p>Dopamine D2 receptor antagonism (B)</p> Signup and view all the answers

Which statement best describes the 'dopamine hypothesis' in relation to antipsychotic action?

<p>Antipsychotics block D2 receptors, decreasing dopamine activity to reduce psychosis, but do not impact negative symptoms. (D)</p> Signup and view all the answers

How do second-generation antipsychotics (SGAs) theoretically reduce the risk of movement disorders compared to first-generation antipsychotics (FGAs)?

<p>SGAs have a weaker dopamine D2 receptor blockade and additional serotonin 5-HT2A antagonism. (B)</p> Signup and view all the answers

What effect does stimulation of 5-HT1A receptors have on dopamine and glutamate release, and how could that impact schizophrenia symptoms?

<p>Increased dopamine release and decreased glutamate release; specifically improves negative symptoms and cognition (A)</p> Signup and view all the answers

Which factor is most important when choosing between antipsychotic medications?

<p>The medication's side effect profile (D)</p> Signup and view all the answers

What is a primary concern associated with initiating olanzapine treatment?

<p>Substantial weight gain and metabolic disturbances (C)</p> Signup and view all the answers

What side effect is more commonly seen with risperidone compared to other second-generation antipsychotics?

<p>Hyperprolactinemia (B)</p> Signup and view all the answers

Why is routine eye examinations recommended for patients taking quetiapine?

<p>Quetiapine use can lead to the development of cataracts. (D)</p> Signup and view all the answers

What is the primary reason clozapine is reserved for use after trials of other antipsychotics have failed?

<p>The risk of severe side effects, including agranulocytosis (C)</p> Signup and view all the answers

A patient taking clozapine must be monitored for which severe adverse effect?

<p>Agranulocytosis (C)</p> Signup and view all the answers

In which clinical situation is ziprasidone most useful due to its formulation?

<p>For acutely psychotic patients in the emergency room (C)</p> Signup and view all the answers

What is a primary advantage of using long-acting injectable antipsychotics (LAIs) over oral antipsychotics?

<p>LAIs guarantee improved adherence to the medication regimen. (D)</p> Signup and view all the answers

A patient is being started on olanzapine pamoate (Zyprexa Relprevv) LAI. What serious adverse effect requires monitoring for at least 3 hours post-injection?

<p>Post-injection delirium/sedation syndrome (A)</p> Signup and view all the answers

Which long-acting injectable antipsychotic requires oral supplementation for a period after the injection is administered?

<p>Aripiprazole Monohydrate (Abilify Maintena) (B)</p> Signup and view all the answers

Which of the following antipsychotics is generally considered to have a relatively safe profile for use during pregnancy?

<p>Haloperidol (C)</p> Signup and view all the answers

A patient with schizophrenia is being treated with an antipsychotic, but continues to experience significant cognitive impairment. Which intervention is MOST appropriate to recommend?

<p>Refer for cognitive rehabilitation therapy (A)</p> Signup and view all the answers

A patient with schizophrenia has not responded to trials of two different antipsychotics at adequate doses and durations. What is the definition of this condition?

<p>Treatment-resistant schizophrenia (B)</p> Signup and view all the answers

In a patient with treatment-resistant schizophrenia, which of the following evaluations is most important to perform?

<p>Ruling out pseudo-resistance (C)</p> Signup and view all the answers

A patient who is a smoker has been stabilized on clozapine. If the patient suddenly stops smoking, what potential change in clozapine levels should be anticipated?

<p>Increased (B)</p> Signup and view all the answers

Which of the following is a common initial treatment for acute dystonia?

<p>Benztropine (B)</p> Signup and view all the answers

To best treat patients with Akathisia, which medication should you avoid?

<p>avoid causative agent (C)</p> Signup and view all the answers

Which class has bent forward, stiffness and pill rolling tremor?

<p>Akinesia (A)</p> Signup and view all the answers

Which is the most common symptom patients will face with Tardive Dyskinesia?

<p>tongue and face ticks (A)</p> Signup and view all the answers

Identify the signs and symptoms that is related to Neuroleptic Malignant Syndrome:

<p>Hyperthermia, rigidity, and delirium (B)</p> Signup and view all the answers

In which scenario would Dantrolene be a treatment?

<p>Neuroleptic Malignant Sydrome (C)</p> Signup and view all the answers

Before reassessing a patient's medication, how long should an antipsychotic be trailed?

<p>1 year (A)</p> Signup and view all the answers

According to schizophrenia recovery rates (25% rule), what percentage of patients are dead after 10 years?

<p>10% (D)</p> Signup and view all the answers

What is true in regards to antipsychotics and anticholinergic effects?

<p>Anticholinergic reduces EPS. (A)</p> Signup and view all the answers

Which second-generation antipsychotic reduces risk of EPS?

<p>Asenapine (C)</p> Signup and view all the answers

What side effects is more important to consider when taking cariprazine?

<p>Motor issues (C)</p> Signup and view all the answers

Which antipsychotic is used in injection form at ERs for acute psychosis?

<p>Ziprasidone (B)</p> Signup and view all the answers

What does Early Psychosis Intervention Network (EPINET) do?

<p>Both A and B (A)</p> Signup and view all the answers

Which is a non-pharmacologic treatment?

<p>CBT (C)</p> Signup and view all the answers

What causes long-term neuroleptics?

<p>Hyperkinetic facial ticks (D)</p> Signup and view all the answers

What is the treatment for Akinesia?

<p>Benztropine (Cogentin) (C)</p> Signup and view all the answers

When should a provider avoid 2 treatment options?

<p>3 failed treatment with monotherapy, which includes Clozapine (C)</p> Signup and view all the answers

What is a medication that leads to a hyperkinetic/facial and tongue movement disorder?

<p>Tardive Dyskinesia (A)</p> Signup and view all the answers

Before diagnosing and treating a patient for Treatment Resistance Schizophrenia, what is important for the practitioner to do?

<p>Rule out pseudo-resistance (C)</p> Signup and view all the answers

Which is an EPS (extrapyramidal symptom)?

<p>Akathisia (D)</p> Signup and view all the answers

What is the primary distinction between positive and negative symptoms of schizophrenia?

<p>Positive symptoms involve an excess or distortion of normal functions, while negative symptoms reflect a decrease in normal functions. (A)</p> Signup and view all the answers

Which of the following represents 'avolition' as a negative symptom of schizophrenia?

<p>Lack of motivation or the ability to initiate and persist in goal-directed activities. (B)</p> Signup and view all the answers

During the prodromal phase of schizophrenia, which of the following behaviors is MOST likely to be observed?

<p>Decline in interest in usual activities and social withdrawal. (B)</p> Signup and view all the answers

How would you describe the 'kindling' phenomenon observed in individuals with schizophrenia?

<p>The gradual worsening of symptoms after each active phase, making the individual more susceptible to future episodes. (A)</p> Signup and view all the answers

According to the diagnostic criteria, what is the PRIMARY timeframe in which disturbances in functioning must be present to meet the criteria for schizophrenia?

<p>At least 6 months. (D)</p> Signup and view all the answers

What is a KEY difference between Schizophreniform disorder and Schizophrenia?

<p>Schizophreniform disorder has a shorter duration of symptoms compared to schizophrenia. (C)</p> Signup and view all the answers

How does schizoaffective disorder DISTINCTLY differ from schizophrenia?

<p>Schizoaffective disorder involves the presence of delusions or hallucinations for at least 2 weeks in the absence of prominent mood symptoms. (C)</p> Signup and view all the answers

Why is early intervention in the treatment of schizophrenia emphasized?

<p>To prevent brain tissue atrophy. (B)</p> Signup and view all the answers

First-generation antipsychotics (FGAs) primarily target what neurotransmitter receptor?

<p>Dopamine D2 receptors. (B)</p> Signup and view all the answers

Why are second-generation antipsychotics (SGAs) often favored over first-generation antipsychotics (FGAs) in clinical practice?

<p>SGAs have a lower risk of movement disorders. (B)</p> Signup and view all the answers

What role is 5-HT2A antagonism believed to serve in the mechanism of action of second-generation antipsychotics?

<p>Reducing the risk of extrapyramidal symptoms and improving cognition. (C)</p> Signup and view all the answers

Why is olanzapine typically NOT recommended as a first-line antipsychotic medication?

<p>Due to its association with significant weight gain. (D)</p> Signup and view all the answers

What is a significant adverse effect associated with Risperidone usage, in comparison to other second-generation antipsychotics?

<p>Increased risk of hyperprolactinemia. (D)</p> Signup and view all the answers

Which of the following potential side effects necessitates routine eye examinations in patients who are on quetiapine?

<p>Cataracts. (A)</p> Signup and view all the answers

Considering its side effect profile, why is clozapine generally reserved as a third-line antipsychotic treatment?

<p>High risk of agranulocytosis. (A)</p> Signup and view all the answers

Which lab value requires continuous monitoring for patients who are prescribed Clozapine?

<p>Absolute Neutrophil Count. (B)</p> Signup and view all the answers

In what clinical setting is ziprasidone particularly useful due to its available formulation?

<p>Acute psychosis in the emergency room. (C)</p> Signup and view all the answers

What is a primary advantage of long-acting injectable antipsychotics (LAIs) compared to oral antipsychotics?

<p>Improved medication adherence. (C)</p> Signup and view all the answers

What potentially serious adverse effect requires monitoring for at least 3 hours post-injection when a patient is administered olanzapine pamoate (Zyprexa Relprevv) LAI?

<p>Post-injection delirium/sedation syndrome. (B)</p> Signup and view all the answers

Which of the long-acting AP formulations requires oral supplementation after the injection is administered?

<p>Aripiprazole Monohydrate (Abilify Maintena). (A)</p> Signup and view all the answers

Which antipsychotic medication is generally considered to have a relatively safer profile for use during pregnancy?

<p>Haloperidol. (A)</p> Signup and view all the answers

In cases where a schizophrenia patient continues to show reduced cognitive impairment, while on an AP medication, what would be the NEXT MOST appropriate recommendation?

<p>Begin Cognitive Behavioral Therapy. (C)</p> Signup and view all the answers

Which statement accurately describes "Treatment Resistance Schizophrenia"?

<p>A patient who doesn't respond to multiple different AP medications. (B)</p> Signup and view all the answers

In a patient with treatment-resistant schizophrenia, what is the MOST important initial step in evaluation?

<p>Reviewing history. (D)</p> Signup and view all the answers

A patient stable on clozapine quits smoking. What adjustments to medication levels should the provider consider, assuming no other changes?

<p>Monitor for signs of clozapine toxicity. (A)</p> Signup and view all the answers

Which of the following is an appropriate treatment option for acute dystonia?

<p>Benztropine. (B)</p> Signup and view all the answers

When using medications to best treat Akathisia, which of these medications should you avoid?

<p>Benztropine. (C)</p> Signup and view all the answers

A patient comes to your office hunched over, with noticeable stiffness. The patient indicates they are suffering “pill rolling tremors”. Which condition is this patient facing?

<p>Parkinsonism. (D)</p> Signup and view all the answers

What signs and symptoms would a patient who has Tardive Dyskinesia commonly face?

<p>Repetitive, involuntary movements, particularly of the face and tongue. (D)</p> Signup and view all the answers

A patient who is presenting as stiff, hot and confused would be suffering from?

<p>Neuroleptic Malignant Syndrome. (D)</p> Signup and view all the answers

While a patient is suffering from Serotonin Syndrome, what are you most likely going to see in a patient’s reflexes?

<p>Hyperreflexia. (A)</p> Signup and view all the answers

Which of the following treatments is MOST appropriate for a patient experiencing Neuroleptic Malignant Syndrome (NMS)?

<p>Administering dantrolene to reduce muscle rigidity. (A)</p> Signup and view all the answers

How long must a medication be trailed to be reconsidered for assessment?

<p>5-6 Weeks. (A)</p> Signup and view all the answers

Based on the schizophrenia recovery data presented, what percentage of patients are deceased after 10 years?

<p>10%. (B)</p> Signup and view all the answers

What correlation is MOST accurate regarding the Anticholinergic effects when pertaining to medications for schizophrenia?

<p>the higher the anticholinergic (ACh) effects, the lower the extrapyramidal. (D)</p> Signup and view all the answers

Due to its indication in injection form, which AP medication is used at some ERs for acute psychosis?

<p>Ziprasidone. (B)</p> Signup and view all the answers

What care does EPINET provide?

<p>EPINET provides resources for clinicians and families. (C)</p> Signup and view all the answers

Which option is a non-pharmacologic treatment.

<p>CBT. (C)</p> Signup and view all the answers

Which medication is MOST related to the risk of hyperkinetic/facial and tongue movements disorder?

<p>Long term Neuroleptics. (D)</p> Signup and view all the answers

Prior to diagnosing a patient with Treatment Resistance Schizophrenia, what is IMPORTANT to ascertain by a provider?

<p>Serum levels of the appropriate AP treatment. (D)</p> Signup and view all the answers

Pertaining to extrapyramidal side effects, which is MOST likely?

<p>Cogwheel Rigidity. (C)</p> Signup and view all the answers

Flashcards

Delusions

False beliefs that are not based in reality

Hallucinations

Sensory experiences that occur without an external stimulus

Difficulty in abstract thinking

Difficulty in abstract thinking. Focus on concrete details.

Affective blunting

Reduced expression of emotions.

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Avolition

Lack of motivation or goal-directed behavior.

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Alogia

Poverty of speech, brief and empty replies.

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Anhedonia

Inability to experience pleasure.

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Asociality

Lack of interest in social interactions.

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Schizophrenia Prodromal Phase

First phase of schizophrenia marked by withdrawal.

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Schizophrenia Active Phase

Phase where positive and negative symptoms are prominent.

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Schizophrenia Residual Phase

Symptoms are less pronounced, similar to prodromal phase.

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Schizophrenia timeline

Diagnostic criteria time period for schizophrenia

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Schizophreniform timeline

Diagnosing Schizophreniform Disorder

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Schizoaffective Disorder

Symptoms including mood episodes and psychotic symptoms occur together.

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Antipsychotics (AP)

Medications that block dopamine (D2) receptors

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APs Mechanism of Action (MOA)

The dopamine hypothesis

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Second Generation Antipsychotics (SGAs)

First line treatment for schizophrenia

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Clozapine (Clozaril)

Medication with anticholinergic properties.

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Clozapine REMS

Risk Evaluation and Mitigation Strategy

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Risperidone (Risperdal)

Long acting injectable used to treat Schizoaffective disorder. Can increase prolactin level.

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Aripiprazole (Abilify)

Treats Schizoaffective disorder

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Neuroleptic Malignant Syndrome

A potentially fatal reaction to antipsychotic drugs

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Anticholinergics

Used for Acute Dystonia

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Akithisia

EPS side effect

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Pseudo Parkinson's

EPS side effect

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Tardive Dyskinesia (TD)

EPS side effect. Constant chewing.

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Positive Symptoms

Added behaviors or experiences such as delusions, hallucinations, disorganized speech, or catatonic behavior.

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Negative Symptoms

Symptoms that reflect a decrease in normal functions, including diminished emotional expression or avolition.

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Disorganized Speech

Difficulty organizing thoughts and expressing them in a clear and coherent manner.

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Disorganized Behavior

Behavior that is unusual, unpredictable, or inappropriate for the situation.

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Catatonic Behavior

Significant reduction in reactivity to the environment, ranging from complete unawareness to resistance to instructions.

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Agitation

State of excessive psychomotor activity, restlessness, and excitement.

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Difficulty Concentrating

Difficulty sustaining focus or attention on tasks or activities.

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Emotional Withdrawal

The reduction in the intensity of emotional expression

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Poor Rapport

Lack of comfort or ease in social situations.

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Passivity

lack of initiative

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Apathetic Social Withdrawal

Withdrawal from social interactions due to lack of interest

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Treatment Significance

The earlier the treatment, the better the outcome, fewer residual symptoms

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Residual Symptoms

Emotional and social withdrawal, listlessness, and trouble concentration

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1-6 months

Psychotic symptoms for at least one month, but less than six.

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Two-week psychotic episode

Characterized by psychotic symptoms (hallucinations, delusions) for at least 2 weeks, but in the absence of prominent mood symptoms.

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Goals of Treatment

To help people with a first episode of psychosis recover.

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Psychotic Disorders

Tradeoffs include

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Treatment Delay

Majority of FEP are untreated for a year

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Majority of FEP

FEP is not treated

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Antipsychotic properties

Requires more education and monitoring

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Anti-Psychotics

D2 receptors.

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Antipsychotics

block dopamine receptors

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Theoretical (SGA) decreased

Decreased risk of movement disorder

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Advantages (SGA)

decreased risk of movement disorders

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Disadvantages (SGA)

Increased risk of metabolic effects (obesity, CAD, Type II DM).

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SGAs

5-HT2A Antagonists.

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SGAs

5-HT1A Agonists.

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PANCE answer

a second-generation anti-psychotic, but not clozapine

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Disadvantages (PANCE answer)

2 successful trials of other APS.

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SGAs (Lanzapine)

Slightly better for patient compliance and ↓ hospitalizations.

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Haldol

long history of safety.

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Bonus

Review Antipsychotic Chart and Pharmacology Videos in Canvas

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Added Bonus

Review “Added Bonus

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Treatment nonadherence

Cognitive impairments.

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Side effect

Treatment resistant positive symptoms (approximately 30%).

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Schizophrenia Hallucinations

False perceptions that are not based on reality

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Schizophrenia: Communication distortion

Exaggerated or unclear verbal communication patterns

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Negative symptom: Blunted affect

Includes reduced emotional expression, poor eye contact, and flat affect

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Negative symptom: Avolition

A persistent lack of desire or motivation to engage in activities

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Negative symptom: Alogia

A state of diminished speaking

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Negative symptom: Anhedonia

The inability to feel pleasure in activities

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Negative symptom: Asociality

Characterized by the desire for social isolation

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Schizophrenia Diagnostic Criteria

Includes prodromal, active and residual phases. Symptoms must last for 6 months

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Schizophreniform Disorder

Symptoms occur for at least a month, but less than six months

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What Increases Relapse?

Decreased medication adherence.

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Adherence challenges.

Medication discontinuation rate of 40-60%.

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Clozapine Side Effects

The need for routine blood monitoring

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Haldol Mechanism of action

Blocks dopamine D2 receptors.

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Risperdal Side Effects

Long term injectable with a rise to a pare

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Which SGAs are known for agonist

Ziprasidone (Geodon), quetiapine and clozapine

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EPS side effects

There are 4 types that you need to look out for

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Acute Dystonia

What side effect could occur when muscles around the eyes and face contracting spasmotically

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What blocks symptoms EPS

Benztropine (Cogentin)

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NML symptoms

Hyperthermia, rigidity, and altered mental status

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Are safe to take while pregnant

Haloperidol (Haldol).

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Long-term movements

Hyperkinetic, facial and tongue movements

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What can you do when TD occurs

Lower dose, switch, or discontinue

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Schizophrenia Treatment

Used to show someone what is really happening.

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Schizophrenia recovery rates

The rate is at 25 percent

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AP Post Treatment Labs and Indices

Same as pretreatment

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Study Notes

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