SBI4U Final Exam Prep - Unit 1: Biochemistry

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Questions and Answers

What is the role of initiator proteins in DNA replication?

  • To synthesize Okazaki fragments
  • To add a methyl group to DNA
  • To recognize the replication origins (correct)
  • To act as molecular scissors

Which type of mutation results in an altered codon that produces a stop codon?

  • Missense mutation
  • Nonsense mutation (correct)
  • Silent mutation
  • Frameshift mutation

What type of bond is formed between a sugar and a nitrogenous base in nucleotides?

  • Phosphodiester bond
  • N-glycosidic bond (correct)
  • Hydrogen bond
  • Ionic bond

What is the principal function of methylases in DNA?

<p>To add methyl groups to prevent cutting by endonucleases (D)</p> Signup and view all the answers

What is the primary role of a cofactor in enzymatic reactions?

<p>To increase the binding ability of enzyme and substrate (A)</p> Signup and view all the answers

Which statement accurately describes the semi-conservative model of DNA replication?

<p>Each daughter strand contains one parental and one new strand. (A)</p> Signup and view all the answers

Which process involves the movement of materials against the concentration gradient?

<p>Active transport (C)</p> Signup and view all the answers

What happens during condensation (dehydration)?

<p>Two molecules combine and water is released (B)</p> Signup and view all the answers

What is the function of glycoproteins in the cell membrane?

<p>Cell signaling and identification (D)</p> Signup and view all the answers

Which statement about enzyme saturation is true?

<p>It can be overcome by increasing substrate concentration (C)</p> Signup and view all the answers

What is the primary role of the parasympathetic nervous system in relation to the heart?

<p>Decreases heart rate (C)</p> Signup and view all the answers

Which of the following describes the Allee effect?

<p>A phenomenon that occurs when population density is too low to survive (A)</p> Signup and view all the answers

What is the key characteristic of a closed population?

<p>No movement of individuals in or out (A)</p> Signup and view all the answers

What do we call the competition that occurs between individuals of the same species?

<p>Intraspecific competition (D)</p> Signup and view all the answers

Which method is best suited for estimating population density of mobile species?

<p>Mark-Recapture method (D)</p> Signup and view all the answers

Which of the following accurately defines the concept of natality?

<p>The number of individuals added through births (C)</p> Signup and view all the answers

The logistic model of population growth is characterized by which of the following?

<p>Growth rate slows down as carrying capacity is approached (C)</p> Signup and view all the answers

What impact does the sympathetic nervous system have on liver function?

<p>Increases release of glucose (C)</p> Signup and view all the answers

What is the primary function of peripheral proteins in the phospholipid bilayer?

<p>They help in cell-cell recognition and communication (D)</p> Signup and view all the answers

Which process involves the movement of water across a selectively permeable membrane?

<p>Osmosis (A)</p> Signup and view all the answers

What is the result of hydrogenation in food preservation?

<p>Production of trans fats (A)</p> Signup and view all the answers

Which statement best describes isomers?

<p>They have the same chemical formula but different arrangements of atoms (D)</p> Signup and view all the answers

What is the primary function of the sodium-potassium pump?

<p>Moves sodium ions out and potassium ions into the cell to maintain an electrochemical gradient (D)</p> Signup and view all the answers

What occurs during phagocytosis?

<p>Large particles, bacteria, or viruses are engulfed in a vesicle (A)</p> Signup and view all the answers

What happens during protein denaturation?

<p>Proteins unfold completely due to breaking bonds (A)</p> Signup and view all the answers

What kind of sugars are classified as reducing sugars?

<p>Sugars with a free -OH group at the anomeric carbon (D)</p> Signup and view all the answers

What type of bond characterizes unsaturated fats?

<p>Cis double bonds (D)</p> Signup and view all the answers

Which structure provides protection and controls access to DNA in a cell?

<p>Nuclear envelope (D)</p> Signup and view all the answers

Which of the following correctly describes the function of glycogen?

<p>Storage of excess glucose in animals (C)</p> Signup and view all the answers

What distinguishes a competitive inhibitor from a non-competitive inhibitor?

<p>Competitive inhibitors bind to an enzyme's active site. (D)</p> Signup and view all the answers

Which of the following best describes tertiary protein structure?

<p>Three-dimensional folding of the protein (A)</p> Signup and view all the answers

Which term refers to a polymer made up of nucleotides?

<p>Nucleic acid (D)</p> Signup and view all the answers

What process involves the transformation of glucose into energy-rich compounds like ATP?

<p>Cellular respiration (B)</p> Signup and view all the answers

What is the main function of the ribosomes in a cell?

<p>Synthesize proteins (D)</p> Signup and view all the answers

Which type of linkage is characteristic of carbohydrates?

<p>Glycosidic bonds (A)</p> Signup and view all the answers

What role do triglycerides play in biological systems?

<p>Long-term energy storage (D)</p> Signup and view all the answers

Which hormone produced by the anterior pituitary stimulates milk production?

<p>Prolactin (B)</p> Signup and view all the answers

What is the primary function of the medulla oblongata?

<p>Site of autonomic nerve control (C)</p> Signup and view all the answers

Which part of the neuron is primarily responsible for receiving stimuli?

<p>Dendrite (A)</p> Signup and view all the answers

Which type of cells form the myelin sheath in the central nervous system?

<p>Oligodendrocytes (B)</p> Signup and view all the answers

What does negative feedback maintain?

<p>Homeostasis (B)</p> Signup and view all the answers

Which structure is NOT part of the reflex arc?

<p>Hypothalamus (B)</p> Signup and view all the answers

What role does the thalamus serve in the sensory pathways?

<p>Relay of sensory information (B)</p> Signup and view all the answers

Which hormone is released by the adrenal medulla during a fight or flight response?

<p>Adrenaline (C)</p> Signup and view all the answers

What physiological process does the receptor perform?

<p>Receives stimulus and sends the message (D)</p> Signup and view all the answers

What is the main function of the parathyroid hormone (PTH)?

<p>Raises calcium levels in the blood (B)</p> Signup and view all the answers

Which lobe of the cerebrum is primarily associated with hearing?

<p>Temporal lobe (A)</p> Signup and view all the answers

What is the function of microglia in the central nervous system?

<p>Serve as immune cells (D)</p> Signup and view all the answers

How does myelin sheath affect nerve impulse conduction?

<p>Speeds up the impulses (C)</p> Signup and view all the answers

Which gland produces melatonin, and what is its primary function?

<p>Pineal gland; regulates sleep-wake cycles (C)</p> Signup and view all the answers

What role do Schwann cells play in the peripheral nervous system?

<p>Produce myelin sheaths (A)</p> Signup and view all the answers

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Flashcards

Active site (enzyme)

A depression in the surface of the globular protein where the substrate binds.

Active Transport

Movement of materials against the concentration gradient, requiring energy; requires specificity in molecules.

ATP

Energy required for cellular function.

Endocytosis

Movement of large molecules into the cell, requiring energy.

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Exocytosis

The movement of large molecules out of the cell, requiring energy.

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Allee effect

A density-dependent phenomenon where a population struggles to survive or reproduce when it's too small.

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Immigration

The movement of individuals into a population.

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Emigration

The movement of individuals out of a population.

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Intraspecific competition

Competition between members of the same species for resources.

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Interspecific competition

Competition between members of different species for resources.

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Exponential model

A model where population growth increases exponentially without limit.

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Logistic model

A model where population growth increases until it starts to slow down and eventually reaches a carrying capacity.

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Mark-Recapture method

A method for estimating population density by capturing, marking, releasing, and recapturing individuals.

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Replication origin

A sequence of nucleotides where DNA replication begins. Provides the starting point for DNA polymerase to begin replicating a strand.

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Restriction endonucleases

Enzymes that cut double-stranded DNA at specific sequences, acting like molecular scissors. They can break both hydrogen bonds between bases and phosphodiester bonds within the backbone.

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PCR (Polymerase Chain Reaction)

The process of making a copy of DNA using a thermal cycler. It involves three stages (denaturation, annealing, elongation) that repeatedly cycle through different temperatures to amplify a targeted DNA region.

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Okazaki fragments

Newly produced DNA fragments synthesized in a discontinuous manner during DNA replication. This occurs on the lagging strand because DNA polymerase can only synthesize in the 5' to 3' direction.

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Replication fork

The shape formed when DNA is unwound by initiator proteins. This allows the DNA polymerase to access the strands and replicate them.

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Saturated Fats

A type of fat that contains only single bonds between carbon atoms.

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Hydrolysis

The process by which water is consumed to break down a molecule into two smaller molecules.

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Hydrogenation

A process where hydrogen is added to unsaturated fatty acids, creating trans fats.

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Transmembrane Protein

A protein that spans the entire lipid bilayer of a cell membrane.

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Isomers

Molecules with the same chemical formula but different arrangements of atoms.

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Osmosis

The movement of water molecules across a selectively permeable membrane from a region of high water concentration to a region of low water concentration.

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Oxidation

The loss of electrons from a molecule or atom.

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Receptor-Mediated Endocytosis

A type of endocytosis that requires a specific receptor on the cell membrane to bind to the substance being taken in. It involves clathrin.

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Membrane proteins

Used in both facilitated diffusion and active transport.

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Electronegativity

The amount of attraction an atom has for a shared pair of electrons in a covalent bond.

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Facilitated diffusion

The transport of molecules across a membrane from an area of high to low concentration.

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Kinase

Hydrolyzes ATP to release energy and phosphorylate a target protein. This often alters the protein's conformation and activity.

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Nonpolar Covalent bond

A type of covalent bond where the atoms are shared equally, resulting in no net charge.

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Polar covalent bond

A type of covalent bond where the atoms are shared unequally, resulting in a partial charge, forming a dipole.

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Ionic bond

A type of bond where an atom is completely donated to another, resulting in a full charge.

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Primary structure

The structure of a protein where the amino acids are linked together by peptide bonds.

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Medulla Oblongata

Location of autonomic nerve control, which regulates involuntary functions like breathing, heart rate, and digestion.

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Microglia

Specialized immune cells found in the central nervous system (CNS). They protect the brain and spinal cord from pathogens and inflammation.

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Midbrain

A relay center that processes visual and auditory reflexes, connecting the eyes and ears to the brain.

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Negative feedback

A mechanism that controls body homeostasis by maintaining a stable internal environment. When a variable changes, it triggers responses to bring it back to normal.

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Nephron

The functional unit of the kidney. Each nephron filters blood, reabsorbs essential substances, and eliminates waste products in urine.

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Neuromuscular junction

The synapse where a neuron communicates with a muscle fiber. This junction transmits nerve signals to initiate muscle contraction.

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Occipital lobe

The lobe of the cerebrum responsible for processing visual information, from color and shape to motion and depth perception.

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Olfactory lobe

The forebrain lobe that receives and processes olfactory information, allowing us to detect and identify smells.

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Oligodendrocytes

Cells that produce the myelin sheath in the central nervous system (CNS). Myelin insulates axons, allowing rapid nerve impulse transmission.

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Parietal lobe

The lobe of the cerebrum responsible for processing touch, temperature, pressure, and pain. It also plays a role in spatial awareness.

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Peripheral Nervous System (PNS)

The part of the nervous system that includes all nerves outside the brain and spinal cord. It transmits sensory information to the CNS and carries motor commands to muscles and glands.

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Pons

The relay station within the brainstem that bridges the cerebellum (responsible for coordination) and the cerebrum (responsible for higher functions).

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Positive feedback

A mechanism that does not maintain homeostasis. It amplifies a change or signal, leading to a definite endpoint or result.

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Prefrontal Cortex

The area in the frontal lobe responsible for executive functions, planning, decision-making, and personality. It's considered the control center for complex cognitive processes.

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Receptor

A specialized structure that detects stimuli from the environment, triggering a response in a neuron. It's the first step in sensory transduction.

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Refractory Period

A brief period of time following an action potential during which a neuron is unable to fire another action potential. This ensures that the neuron has time to recover and reset its electrochemical state.

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Reticular Formation

This allows background information to be inhibited or filtered out, allowing us to focus on important sensory input.

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Satellite Cells

These cells provide physical support and insulation to neurons in the peripheral nervous system (PNS). They create a supportive environment for nerve fibers and help maintain their functionality.

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Schwann Cells

Cells that produce the myelin sheath in the peripheral nervous system (PNS). They wrap around axons, insulating them and allowing for faster nerve impulse conduction.

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Synaptic Cleft

The small gap between two neurons, where nerve signals travel.

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Temporal Lobe

The lobe of the cerebrum responsible for processing auditory information, including sound recognition, speech comprehension, and memory.

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Thalamus

The sensory relay center of the brain that receives and processes various sensory stimuli, including pain, temperature, and pressure.

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Wernicke's Area

An area in the cerebral cortex responsible for processing the grammatical rules of language, enabling us to speak in a fluent and grammatically correct manner.

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Study Notes

SBI4U Final Exam Prep - Unit 1: Biochemistry

  • Active site (enzyme): A depression on a globular protein where a substrate binds.
  • Active transport: Movement of materials against a concentration gradient, requiring energy; specific to molecules.
  • ATP: Cellular energy required for function.
  • Benedict's solution: Identifies reducing sugars.
  • Coenzyme: Similar to cofactors but are organic, non-protein molecules.
  • Cofactor: Inorganic ions in the active site that increase enzyme-substrate binding.
  • Condensation (dehydration): Water released to combine two molecules into one.
  • Coupled channel: Uses active transport-created concentration to passively transport other molecules.
  • Diffusion: Random molecule movement down a concentration gradient.
  • Electronegativity: An atom's ability to attract electrons when forming a bond.
  • Endocytosis: Large molecule uptake into cells, requiring energy.
  • Enzyme: Globular protein that speeds up reactions by lowering activation energy, held together by hydrogen bonds and other intermolecular forces.
  • Enzyme saturation: Enzyme concentration increase has no effect on reaction rate, overcome by increasing substrate.
  • Essential amino acids: Eight amino acids that the body can't produce.
  • Exocytosis: Large molecule release from cells, requiring energy.
  • Facilitated diffusion: Movement of molecules through integral proteins, requiring specificity.
  • Feedback inhibition: Product inhibits earlier stages in the production pathway.
  • Glycolipids: Carbohydrates attached to phospholipids in the cell membrane; acts as markers.
  • Glycoproteins: Carbohydrate chains attached to membrane proteins; serves for cell recognition and communication.
  • Hydrogenation: Adding hydrogen to unsaturated fatty acids (creating trans fats), often in food preservation.
  • Hydrolysis: Water consumed to break a substance into two.
  • Isomer: Same chemical formula, different arrangement of atoms.
  • Lateral diffusion (phospholipid bilayer): Phospholipids and proteins move sideways within the membrane.
  • Osmosis: Water movement across a selectively permeable membrane.
  • Oxidation: Loss of electrons.
  • Peripheral proteins: Membrane proteins located on the surface of the lipid bilayer.
  • Phagocytosis: Cell engulfing particles, bacteria, viruses in a vesicle.

SBI4U Final Exam Prep - Unit 2: Molecular Genetics

  • Antiparallel: DNA strands run parallel but in opposite directions.
  • Blunt ends: DNA fragments without overhangs.
  • Conservative model: DNA replication forms completely new DNA double helix.
  • Dispersive model: DNA replication fragments from original strands recombine in new strands
  • DNA gyrase: Relaxes DNA tension ahead of the helicase during replication.
  • DNA helicase: Unwinds DNA during replication by breaking hydrogen bonds.
  • DNA ligase: Connects Okazaki fragments in DNA replication.
  • DNA polymerase I: Replaces RNA primers with DNA during replication, proofreads.
  • DNA polymerase III: Synthesizes DNA from primer by building complementary bases.
  • Exons: DNA coding regions.
  • Frameshift mutation: Insertion or deletion of bases, altering codon sequence.
  • Gel electrophoresis: Separates DNA fragments by size and charge.
  • Hydrogen bond: Weak bond between complementary DNA base pairs.
  • Initiator proteins: Identify replication origins, opening the replication bubble.
  • Introns: Non-coding regions of DNA.
  • Methylases: Enzymes that add methyl groups to DNA, protecting it from restriction enzymes.
  • Mis-sense mutation: Changed codon results in a different amino acid.
  • N-glycosidic bond: Connects sugar and base in the nucleotides.
  • Non-sense mutation: Altered codon becomes a stop codon, prematurely stopping translation.
  • Nucleotide: DNA and RNA building blocks, containing phosphate, sugar, and base.
  • Okazaki fragments: Small fragments of DNA synthesized during discontinuous replication.
  • PCR: Amplifies DNA quantity using a thermal cycler.
  • Phosphodiester bond: Connects phosphate groups to sugar in nucleotides.
  • Purines: Adenine and guanine (double-ring nitrogenous bases).
  • Pyrimidines: Cytosine, thymine, and uracil (single-ring nitrogenous bases).
  • Recombinant DNA: Artificially formed DNA by combining DNA pieces.
  • Replication fork: Y-shaped region where DNA replicates during DNA replication
  • Replication origin: Site on DNA where replication starts.
  • Restriction endonuclease: Cuts DNA at specific sequences to produce DNA fragments.
  • RNA primase: Synthesizes RNA primers to begin DNA synthesis.
  • Semi-conservative model: DNA strands consist of one new and one old strand.
  • Silent mutation: DNA change that results in the same amino acid during translation
  • SSBs: Hold DNA strands apart during replication by preventing hydrogen bonds from reforming.
  • Sticky Ends: DNA fragments with overhangs that allow complementary base pairing.
  • Substitution mutation: One base is replaced by another.

SBI4U Final Exam Prep - Unit 3: Metabolic Processes

  •  Taq polymerase: Heat resistant DNA polymerase in PCR
  • Telomeres: Repetitive ends of DNA that act as buffers and prevent chromosome ends from being damaged

SBI4U Final Exam Prep - Unit 4: Homeostasis

  • Acetylcholine: Neurotransmitter at neuromuscular junctions.
  • Acetylcholinesterase: Breaks down acetylcholine to acetic acid and choline.
  • ADH: Controls kidney water permeability.
  • Antagonistic hormones: Hormones with opposite effects.
  • Astrocytes: Provide support to neurons.
  • Autonomic nervous system: Controls involuntary functions.
  • Broca's Area: Involved in speaking ability.
  • Central Nervous System: Brain and spinal cord.
  • Cerebellum: Coordinates movement and balance.
  • Cerebral cortex: Outer layer of the brain responsible for higher functions.
  • Cerebrospinal fluid: Cushions and protects the brain and spinal cord.
  • Cerebrum: The most developed part of the brain in humans.
  • Control center/integrator: Relays messages to appropriate locations for response.
  • Corpus callosum: Connects cerebral hemispheres.
  • Diuretic: Inhibits ADH production, increasing urine output.
  • Effector: Responds to messages, causing changes to restore balance.
  • Frontal lobe: Involved in intellectual activity.
  • Glial cells: Provide support to neurons.
  • Homeostasis: Maintaining internal balance.
  • Hypersecretion: Overproduction of hormones.
  • Hyposecretion: Underproduction of hormones.
  • Limbic system: Structures involved in emotions and drives.
  • Medulla Oblongata: Controls basic life functions.
  • Microglia: Immune cells of the CNS.
  • Midbrain: Relay center for sensory information.
  • Negative feedback: Maintains internal stability.
  • Nephron: Functional unit of the kidney.
  • Neuromuscular junction: Synapse between neuron and muscle.
  • Occipital lobe: Involved in vision.

SBI4U Final Exam Prep - Unit 5: Population Dynamics

  • Allee effect: Population decline due to low numbers or densities impacting survival.
  • Carnivory: Meat-eating behaviour of organisms.
  • Closed population: No population movement in or out.
  • Coevolution: Two or more species evolving in response to each other.
  • Emigration: Movement of individuals out of a population.
  • Exploitative competition: Limiting resources are utilized by organisms to reduce food.
  • Exponential model: Unchecked population growth.
  • Fecundity: Capacity or potential to reproduce.
  • Fertility: Actual reproductive rate.
  • Herbivory: Consumption of plants by animals.
  • Immigration: Moving into a population.
  • Interference competition: One species actively prevents another from accessing resources.
  • Interspecific competition: Competition between different species.
  • Intraspecific competition: Competition between members of the same species.
  • Logistic model: Population growth that levels off as it nears carrying capacity.
  • Mark-recapture method: Estimating population size by capturing, marking, and recapturing.
  • Mortality: Death rate within a population over a given period
  • Natality: Birth rate in a population over a period.
  • Open population: Individuals move in or out of a population.
  • Quadrat method: Counting organisms within a given area.
  • Resource partitioning: Species avoid competition by using different resources/spaces.

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