Sarcomeres and Calcium Signaling
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Questions and Answers

Which channel is enriched in the junctional regions of the SR in cardiac muscle sarcomeres?

  • Ryanodine receptors (correct)
  • Na+ - Ca2+ antiporter
  • Sarcolemmal Ca2+ pump
  • Sarcoplasmic endoplasmic reticulum calcium-ATPase
  • What initiates the cross-bridge cycle in cardiac muscle?

  • Binding of troponin C to Ca2+ (correct)
  • Extrusion of Ca2+ from the cell
  • Influx of Ca2+ during an action potential
  • Ca2+ release from the SR
  • How is Ca2+ extruded from cardiac muscle cells?

  • By influx of Ca2+ during an action potential
  • Through the sarcolemmal Na+ - Ca2+ antiporter and sarcolemmal Ca2+ pump (correct)
  • Through the sarcoplasmic endoplasmic reticulum calcium-ATPase (SERCA)
  • By binding to troponin C
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