Podcast
Questions and Answers
What was the main product isolated by Traugott Sandmeyer when he attempted to synthesize phenylacetylene?
What was the main product isolated by Traugott Sandmeyer when he attempted to synthesize phenylacetylene?
- Chlorobenzene (correct)
- Iodobenzene
- Bromobenzene
- Fluorobenzene
What is the Sandmeyer reaction an example of?
What is the Sandmeyer reaction an example of?
- Radical-nucleophilic aromatic substitution (correct)
- Free radical addition
- Nucleophilic aliphatic substitution
- Electrophilic aromatic substitution
What other reaction has been developed as a 'Sandmeyer-type' reaction in more recent times?
What other reaction has been developed as a 'Sandmeyer-type' reaction in more recent times?
- Trifluoromethylation (correct)
- Reduction
- Oxidation
- Decarboxylation
Which of the following does not require a metal catalyst and is not usually referred to as a Sandmeyer reaction?
Which of the following does not require a metal catalyst and is not usually referred to as a Sandmeyer reaction?
Which metal catalyst is commonly employed in Sandmeyer reactions for cyanation?
Which metal catalyst is commonly employed in Sandmeyer reactions for cyanation?
What is the IUPAC Gold Book definition of an intermediate in a chemical reaction?
What is the IUPAC Gold Book definition of an intermediate in a chemical reaction?
In the reaction A + B ⟶ X ⟶ C + D, what is X?
In the reaction A + B ⟶ X ⟶ C + D, what is X?
What is the main characteristic of a reactive intermediate?
What is the main characteristic of a reactive intermediate?
How is the phrase 'reaction intermediate' often abbreviated?
How is the phrase 'reaction intermediate' often abbreviated?
What does a reaction intermediate not appear in for the overall reaction?
What does a reaction intermediate not appear in for the overall reaction?
Study Notes
Sandmeyer Reaction
- Traugott Sandmeyer isolated diazonium salts when attempting to synthesize phenylacetylene
- The Sandmeyer reaction is an example of a nucleophilic aromatic substitution reaction
Recent Developments
- The Chan-Lam reaction is a recent example of a 'Sandmeyer-type' reaction
Characteristics of Sandmeyer Reactions
- Sandmeyer reactions typically require a metal catalyst
- The copper(I) cyanide catalyst is commonly employed for cyanation in Sandmeyer reactions
- The Chan-Lam reaction does not require a metal catalyst and is not usually referred to as a Sandmeyer reaction
Reaction Intermediates
- According to the IUPAC Gold Book, an intermediate in a chemical reaction is a molecular entity with a lifetime sufficiently long to possess measurable properties
- In the reaction A + B ⟶ X ⟶ C + D, X is an intermediate
- A reactive intermediate has a short lifetime and is usually highly reactive
- The phrase 'reaction intermediate' is often abbreviated as 'intermediate'
- A reaction intermediate does not appear in the overall reaction equation
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge of the Sandmeyer reaction, a chemical process for synthesizing aryl halides from aryl diazonium salts using copper reagents. Learn about the unique transformations it enables on benzene, such as halogenation, cyanation, trifluoromethylation, and hydroxylation. Discover the history and significance of this reaction in organic chemistry.
