Salivary Glands Anatomy and Physiology

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Questions and Answers

Which of the following salivary glands is responsible for secreting the majority (approximately 60-65%) of total saliva?

  • Minor salivary glands
  • Submandibular gland (correct)
  • Sublingual gland
  • Parotid gland

The parotid duct opens into the oral cavity by passing through which muscle?

  • Buccinator (correct)
  • Masseter
  • Pterygoid
  • Temporalis

What anatomical landmark is used to locate the opening of the submandibular duct?

  • Palatine tonsils
  • Sublingual caruncles (correct)
  • Uvula
  • Incisive papilla

What is the range for the number of ducts of Rivinus that drain the sublingual glands?

<p>8-20 (D)</p> Signup and view all the answers

Which of the following is a common initial treatment strategy for sialolithiasis?

<p>Hydration and stimulation of secretion (C)</p> Signup and view all the answers

In which major salivary gland are salivary stones most commonly found?

<p>Submandibular gland (B)</p> Signup and view all the answers

What is the most accurate description of the cause of sialolithiasis?

<p>Calcified deposits blocking salivary ducts (D)</p> Signup and view all the answers

What type of epithelium characterizes the Intercalated ducts within the salivary glands?

<p>Low cuboidal (D)</p> Signup and view all the answers

Which of the following best describes the function of myoepithelial cells in salivary glands?

<p>Contract to aid in saliva secretion (D)</p> Signup and view all the answers

Which type of cell predominates in the parotid gland, influencing its primary secretion?

<p>Serous cells (A)</p> Signup and view all the answers

Which of the following components of saliva is primarily involved in the initiation of starch digestion?

<p>α-amylase (C)</p> Signup and view all the answers

Which of the following best describes the role of R-protein (haptocorrin) found in saliva?

<p>Assisting in vitamin B12 absorption (C)</p> Signup and view all the answers

Which of these salivary components primarily facilitates protection against pathogens in the oral cavity?

<p>Immunoglobulin A (IgA) (D)</p> Signup and view all the answers

Which of the following best describes the primary function of bicarbonate ions (HCO3-) in saliva?

<p>Neutralization of acids (A)</p> Signup and view all the answers

Which of the following is LEAST likely to be a cause of Xerostomia?

<p>Bacterial infection (D)</p> Signup and view all the answers

Which of the following is a common symptom of Xerostomia?

<p>Dental caries and ulceration (D)</p> Signup and view all the answers

What is meant by the term Salivon?

<p>The functional unit of the saliva gland (D)</p> Signup and view all the answers

What is the composition of the primary secretion from acini?

<p>Isotonic (C)</p> Signup and view all the answers

What function are the intercalated ducts responsible for?

<p>They modify saliva through electrolyte reabsorption and secretion. (C)</p> Signup and view all the answers

During the secondary modification of saliva in the ducts, which electrolytes are absorbed?

<p>Sodium and Chloride (A)</p> Signup and view all the answers

During the secondary modification of saliva in the ducts, which electrolytes are secreted?

<p>Potassium and Bicarbonate (A)</p> Signup and view all the answers

In an actively secreting salivary gland, how does the concentration of sodium ($Na^+$) in saliva typically compare to its concentration in plasma?

<p>Significantly lower in saliva (A)</p> Signup and view all the answers

What is the expected impact on salivary HCO3- concentration during active secretion in a patient with cystic fibrosis, according to the ductal modification model?

<p>Concentration would significantly decrease (C)</p> Signup and view all the answers

Which condition is associated with saliva flow rate decreasing?

<p>Asleep (A)</p> Signup and view all the answers

Which branch of the autonomic nervous system primarily stimulates profuse secretion of watery saliva?

<p>Parasympathetic nervous system (A)</p> Signup and view all the answers

Activation of the sympathetic nervous system has what affect on saliva volume?

<p>Small volume rich in proteins and mucus (C)</p> Signup and view all the answers

Which cranial nerve provides parasympathetic innervation to the parotid gland?

<p>CN IX (Glossopharyngeal) (C)</p> Signup and view all the answers

Besides autonomic factors, what other conditions can affect salvia secretion?

<p>All of the above (D)</p> Signup and view all the answers

What is the affect of parasympathetic stimulation on the blood supply to the salivary glands?

<p>Vasodilation (C)</p> Signup and view all the answers

What affect on the blood supply to the salivary glands does Bradykinin have?

<p>Vasodilation (B)</p> Signup and view all the answers

Which of the following mechanisms explains the impact of bradykinin on salivary gland blood supply?

<p>Conversion of bradykininogen to bradykinin, leading to vasodilation (A)</p> Signup and view all the answers

How does sympathetic stimulation generally affect blood supply to the salivary glands?

<p>Vasoconstriction, reducing blood flow and potentially altering saliva composition (C)</p> Signup and view all the answers

Why is saliva important to lubrication, digestion and protection?

<p>Because it contains electrolytes, buffers, and proteins. (A)</p> Signup and view all the answers

How would the saliva differ from the submandibular and sublingual glands, and parotid gland?

<p>Saliva is produced from various glands that each have a different composition (A)</p> Signup and view all the answers

Which statement best summarizes the process of saliva production and modification?

<p>Acini secrete a primary fluid that is then modified by the ducts through electrolyte exchange. (D)</p> Signup and view all the answers

Which of the following is responsible for non-neuronal stimuli exist?

<p>Smell of food (A)</p> Signup and view all the answers

Flashcards

Salivary Glands

The three main paired salivary glands: parotid, submandibular, and sublingual glands.

Parotid Duct

Passes through the buccinator muscle, opening into the oral cavity opposite the maxillary second molar.

Submandibular Duct

Travels between the sublingual gland and genioglossus, draining into the mouth through the sublingual caruncles either side of the frenulum of the tongue.

Sublingual Ducts

8-20 ducts draining sublingual glands; some join the submandibular duct, others open separately at the sublingual folds.

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Sialolithiasis

Calcified deposits blocking salivary ducts causing gland pain, swelling, inflammation, and/or infection.

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Salivary Gland Duct Structure

Acinus, intercalated duct, striated duct, interlobular duct, lobar duct, main duct

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Salivon

The functional unit of the salivary glands, consisting of acini, myoepithelial cells, intercalated duct, serous cells, mucous cells and salivary duct.

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Primary Secretion in Acini

Acinar cells secrete isotonic, plasma-like fluid; mucin glycoprotein, proline-rich protein, and IgA.

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Secondary Modification in Ducts

Ducts modify saliva by secreting lysozyme & K+, reabsorbing Cl- & Na+ to produce hypotonic output

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Xerostomia

A condition caused by decreased blood supply and/or the secretory function leading to dental issues and difficulty speaking/tasting/chewing/swallowing.

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Saliva for Lubrication

Fluid and mucus.

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Saliva for Digestion

Alpha-amylase (starch digestion) and lingual lipase (lipid digestion).

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Saliva for Protection

Lysozyme, lactoferrin, IgA, thiocyanate, proline-rich proteins, mucus and bicarbonate.

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Causes of "Dry Mouth"

Decreased blood supply, secretory function, and nerve function.

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The course of the submandibular duct

Located between sublingual gland and genioglossus. Drains into the sublingual caruncles either side of the frenulum of the tongue.

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Primary Secretion Tonicity

Isotonic, Plasma-like

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Primary Secretion Electrolytes

Na+, Cl-

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Parasympathetic Innervation

Sublingual and submandibular glands via CNVII, parotid via CNIX.

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Parasympathetic Blood Supply effect

Vasodilation via Ach & VIP release.

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Sympathetic Saliva Effect

Small volume, rich in proteins and mucus.

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Sympathetic Blood Supply effect

Vasoconstriction via norepinephrine.

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Study Notes

Functional Anatomy and Physiology of Salivary Glands

  • The session covers the functional anatomy and physiology of salivary glands

Learning Outcomes

  • The gross anatomy of salivary glands and their ducts are covered
  • The microanatomical structure of salivary glands are covered
  • The composition of saliva and the functions of the constituents are identified
  • The process of saliva production and how it is controlled is described

Salivary Glands

  • Approximately 90% of saliva comes from 3 main gland pairs: parotid, submandibular, and sublingual glands
  • The remaining 10% of saliva is produced by numerous smaller glands

Parotid Duct

  • The parotid duct passes through the buccinator muscle
  • The duct opens into the oral cavity on the inner cheek surface, opposite the maxillary second molar

Submandibular Duct

  • The submandibular duct, also known as Wharton's duct, runs between the sublingual gland and genioglossus
  • The duct drains into the mouth through the sublingual caruncles on either side of the tongue frenulum

Sublingual Ducts

  • Between 8-20 ducts of Rivinus drain the sublingual glands
  • Some ducts form the sublingual duct of Bartholin, joining the submandibular duct
  • Other ducts drain separately into the sublingual folds on either side of the tongue frenulum

Sialolithiasis (Salivary Stones)

  • Calcified deposits can block salivary ducts, causing pain and swelling, potentially leading to inflammation or infection
  • Sialolithiasis are most common in males aged 30-60, specifically in the submandibular glands
  • Sialolithiasis are less common in the parotid and rare in the sublingual and smaller glands

Sialolithiasis Treatments

  • Hydration and stimulating secretion helps flushing smaller stones
  • Massage can encourage stone expulsion
  • Sialendoscopy
  • Surgical removal of stones (sialectomy) or the affected gland is possible

Salivary Gland Histology

  • The parotid gland produces serous saliva
  • The total secretion from parotid glands is 20-25%
  • The sublingual glands produce a mucus/serous mix of saliva
  • The submandibular gland produces a serous/mucus mix of saliva
  • The total secretion is 60-65%
  • Other glands produce mucus saliva, accounting for 10% of secretion

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