Rough Endoplasmic Reticulum (RER) Functions

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What is the function of polyribosomes attached to the membranes of the endoplasmic reticulum?

Translate mRNAs coding for membrane proteins of the ER, the Golgi apparatus, or the cell membrane, enzymes to be stored in lysosomes and proteins to undergo exocytosis from secretory vesicles.

Where do proteins, glycoproteins, and lipoproteins get synthesized in the cell?

In the Endoplasmic Reticulum (ER)

Why does the Rough Endoplasmic Reticulum (RER) stain with basic dyes?

Due to the presence of negatively charged rRNA in the ribosomes attached to it

What type of cells have a more prominent Endoplasmic Reticulum?

Cells actively synthesizing proteins, e.g., immunoglobulin secreting plasma cells

What can be visualized through light microscopy in the Rough Endoplasmic Reticulum?

Masses of material staining with basic dyes

In which type of cells is the visibility of the Rough Endoplasmic Reticulum increased?

Cells that are highly secretory, such as Nissl substance in neurons and exocrine pancreatic acinar cells

What is the network of interconnecting membranes in the cell that encloses channels or cisternae?

The Endoplasmic Reticulum

What is the purpose of polyribosomes in protein synthesis?

To translate mRNAs into proteins

Where are proteins synthesized for use within the cytosol or for import into the nucleus and certain organelles?

On polyribosomes

What type of proteins are synthesized on polyribosomes attached to the membranes of the Endoplasmic Reticulum?

Membrane proteins of the ER, the Golgi apparatus, or the cell membrane, enzymes to be stored in lysosomes and proteins to undergo exocytosis from secretory vesicles

Learn about the structure and functions of Rough Endoplasmic Reticulum (RER), including its role in protein synthesis and production of membrane associated proteins. Understand the characteristics of rough ER and its connection to the perinuclear space.

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