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Questions and Answers
What is the drug class of Rosuvastatin (Crestor)?
Antihyperlipidemia: HMG-CoA reductase inhibitor
What is the recommended dosage for Rosuvastatin (Crestor)?
PO: 5-40 mg/d; max: 40 mg/d
Which of the following are contraindications for Rosuvastatin?
What are some cautions to consider when prescribing Rosuvastatin?
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What effects can drug interactions have on Rosuvastatin?
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What is the therapeutic effect of Rosuvastatin?
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What are some common side effects of Rosuvastatin?
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What are some adverse reactions to Rosuvastatin?
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What should be assessed in patients taking antihyperlipidemics like statins?
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What is the pregnancy category for Rosuvastatin?
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The patient's cholesterol level will be ___
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Study Notes
Rosuvastatin (Crestor) Overview
- Drug Class: HMG-CoA reductase inhibitor, used to manage antihyperlipidemia.
- Dosage: Administered orally at doses of 5-40 mg per day, with a maximum of 40 mg per day.
Contraindications
- Not for use in patients with active liver disease or during pregnancy.
- Caution required for individuals with a history of liver disease, heavy alcohol intake, trauma, severe metabolic disorders, or uncontrolled seizures.
Drug-Lab-Food Interactions
- Decreased effectiveness when taken with antacids, phenytoin, and propranolol.
- May raise digoxin levels and oral contraceptive efficacy.
- Increased effectiveness observed when used with macrolide antibiotics and antifungals.
Therapeutic Effects and Mechanism of Action
- Reduces cholesterol levels by lowering LDL and triglycerides.
- Functions by inhibiting the enzyme HMG-CoA reductase, crucial for hepatic cholesterol production.
Side Effects
- Common side effects include headaches, rash, pruritus, constipation, and diarrhea; however, these are considered rare.
Adverse Reactions
- Serious risks involve rhabdomyolysis, myalgia, photosensitivity, hyperglycemia, and elevated liver enzymes.
Nursing Considerations
- Assessment: Record vital signs and baseline serum chemistry (cholesterol, triglycerides, AST, ALT, CPK).
- Medication history is critical, particularly for patients with liver disorders.
- Pregnancy category: X, indicating contraindications for use during pregnancy.
Planning and Patient Goals
- Aim for a measurable reduction in the patient's cholesterol level during treatment.
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Description
Test your knowledge on Rosuvastatin, including its drug class, dosage, contraindications, and interactions. This quiz provides key information essential for understanding the medication's use and precautions. Perfect for pharmacy students and healthcare professionals.
