6 Questions
What is the role of the pentose phosphate pathway in the glutathione peroxidase reaction of erythrocytes?
To generate reducing power (NADPH) for the regeneration of reduced glutathione
What is the primary function of the pentose phosphate pathway in erythrocytes?
To provide ribose-5-phosphate for nucleotide synthesis
Why is the pentose phosphate pathway considered essential for erythrocytes?
Because erythrocytes lack mitochondria for other energy-producing pathways
How does the pentose phosphate pathway contribute to protecting erythrocytes from oxidative damage?
By producing NADPH which regenerates reduced glutathione to combat oxidative stress
How does the deficiency of glucose-6-phosphate dehydrogenase (G6PD) enzyme affect the pentose phosphate pathway in erythrocytes?
It impairs NADPH production, leading to increased susceptibility to oxidative damage
Which statement best describes the relationship between the pentose phosphate pathway and red blood cells (erythrocytes)?
The pentose phosphate pathway is crucial for red blood cells as it provides NADPH and ribose-5-phosphate.
Explore the importance of a constant supply of 1 NADPH in supporting reductive biosynthesis and reversing the effects of reactive oxygen species (ROS) in sensitive cellular structures. Dive into the mechanisms that help maintain cellular balance.
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