Podcast
Questions and Answers
Which complex is responsible for the assembly of a pre-initiation complex with general transcription factors and RNA Polymerase II?
Which complex is responsible for the assembly of a pre-initiation complex with general transcription factors and RNA Polymerase II?
- TFIIB
- TFIIA
- TFIIF
- TFIID (correct)
Which subunit of TFIID binds directly to the TATA box in the core promoter?
Which subunit of TFIID binds directly to the TATA box in the core promoter?
- TFIIA
- TFIIB
- TBP (correct)
- TAF
Which transcription factor binds to the BRE sequence in the core promoter?
Which transcription factor binds to the BRE sequence in the core promoter?
- TFIIF
- TFIIA
- TFIIB (correct)
- TFIID
Which complex functions as a link between general and specific transcription factors during the initiation step?
Which complex functions as a link between general and specific transcription factors during the initiation step?
What is the main function of TFIIH?
What is the main function of TFIIH?
What is the role of CPSF in the termination step of transcription?
What is the role of CPSF in the termination step of transcription?
Which enzyme is responsible for transcription?
Which enzyme is responsible for transcription?
What is the direction of RNA synthesis during transcription?
What is the direction of RNA synthesis during transcription?
Which type of polymerase is involved in transcription in prokaryotes?
Which type of polymerase is involved in transcription in prokaryotes?
What are the protein subunits of prokaryotic RNA Polymerases?
What are the protein subunits of prokaryotic RNA Polymerases?
What is the function of the sigma (s) subunit in prokaryotic transcription?
What is the function of the sigma (s) subunit in prokaryotic transcription?
What is the difference between a closed and open promoter complex?
What is the difference between a closed and open promoter complex?
Which enzyme transcribes rRNA genes in the nucleolus?
Which enzyme transcribes rRNA genes in the nucleolus?
How many rRNA genes are present in a human diploid cell?
How many rRNA genes are present in a human diploid cell?
What is the core promoter for rRNA genes located?
What is the core promoter for rRNA genes located?
Which transcription factor binds to the core promoter of rRNA genes to promote assembly of a transcriptionally-active RNA Polymerase I complex?
Which transcription factor binds to the core promoter of rRNA genes to promote assembly of a transcriptionally-active RNA Polymerase I complex?
Which enzyme transcribes most genes to synthesize mRNA?
Which enzyme transcribes most genes to synthesize mRNA?
What is the core promoter of a gene defined as?
What is the core promoter of a gene defined as?
Which RNA Polymerase is responsible for transcribing pre-ribosomal RNA in eukaryotes?
Which RNA Polymerase is responsible for transcribing pre-ribosomal RNA in eukaryotes?
What is the role of the s subunit in RNA Polymerase holoenzyme?
What is the role of the s subunit in RNA Polymerase holoenzyme?
What is the consensus sequence for the -35 region of the promoter recognized by the s70 subunit in prokaryotes?
What is the consensus sequence for the -35 region of the promoter recognized by the s70 subunit in prokaryotes?
What is the function of Gyrase in prokaryotes during transcription?
What is the function of Gyrase in prokaryotes during transcription?
How does template-directed termination occur in prokaryotic transcription?
How does template-directed termination occur in prokaryotic transcription?
What are cis-acting elements in transcriptional regulation?
What are cis-acting elements in transcriptional regulation?
Which type of RNA Polymerase is responsible for the production of ribosomal RNA (rRNA)?
Which type of RNA Polymerase is responsible for the production of ribosomal RNA (rRNA)?
Which of the following is NOT a component required for eukaryotic RNA Polymerases to initiate transcription of a gene?
Which of the following is NOT a component required for eukaryotic RNA Polymerases to initiate transcription of a gene?
What is the main difference between cis-acting elements and trans-acting factors in the regulation of transcription?
What is the main difference between cis-acting elements and trans-acting factors in the regulation of transcription?
What are the main types of sequence elements in the core promoter of a gene?
What are the main types of sequence elements in the core promoter of a gene?
Which of the following is NOT involved in the initiation step of transcription of all eukaryotic genes?
Which of the following is NOT involved in the initiation step of transcription of all eukaryotic genes?
What is the role of the C-terminal domain of RNA Polymerase II in the elongation step of transcription?
What is the role of the C-terminal domain of RNA Polymerase II in the elongation step of transcription?