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Questions and Answers

Which enzyme do rifamycins inhibit to exert their antibacterial effect?

  • Helicase
  • Ligase
  • RNA polymerase (correct)
  • DNA polymerase

Which of the following is an example of rifamycin?

  • Azithromycin
  • Rifampicin (correct)
  • Clarithromycin
  • Ciprofloxacin

Against which type of bacteria are rifamycins particularly active?

  • Mycobacteria (correct)
  • Spirochetes
  • Gram-negative bacteria
  • Gram-positive bacteria

What is the mechanism of action of oxazolidinones?

<p>Inhibition of bacterial translation by targeting the binding of N-formylmethionyl-tRNA to the ribosome (C)</p> Signup and view all the answers

Which type of bacteria are oxazolidinones particularly active against?

<p>Gram-positive aerobic bacteria (A)</p> Signup and view all the answers

Which of the following is an example of an oxazolidinone?

<p>Linezolid (D)</p> Signup and view all the answers

How do aminoglycosides work?

<p>Inhibition of bacterial translation by targeting 30s ribosomal subunit (B)</p> Signup and view all the answers

Which cellular component do aminoglycosides target to exert their antibacterial effect?

<p>30s ribosomal subunit (C)</p> Signup and view all the answers

What is the primary mechanism of action of aminoglycosides?

<p>Inhibition of bacterial translation (A)</p> Signup and view all the answers

example of aminoglycoside?

<p>Neomycin (A)</p> Signup and view all the answers

example of aminioglycoside

<p>Gentamicin (B)</p> Signup and view all the answers

example of aminioglycoside

<p>Kanamicin (C)</p> Signup and view all the answers

aminoglycoside?

<p>Amikacin (B)</p> Signup and view all the answers

Which of the following is NOT an example of an aminoglycoside?

<p>Rifampicin (C)</p> Signup and view all the answers

Which of the following is a correct example of an aminoglycoside?

<p>Dibekacin (D)</p> Signup and view all the answers

Which of the following is an example of an oxazolidinone?

<p>Linezolid (D)</p> Signup and view all the answers

Which of the following is NOT an example of aminoglycoside?

<p>Vancomycin (C)</p> Signup and view all the answers

Which of the following is an example of an aminoglycoside?

<p>Isepamicin (D)</p> Signup and view all the answers

Against which type of bacteria are aminoglycosides particularly active?

<p>Gram-negative bacteria (B)</p> Signup and view all the answers

Which type of bacteria are aminoglycosides NOT active against?

<p>Anaerobic bacteria (C)</p> Signup and view all the answers

Among the following, which bacterium is NOT mentioned as being susceptible to aminoglycosides?

<p>Streptococcus pneumoniae (C)</p> Signup and view all the answers

What is the primary target of tetracyclines in bacterial cells?

<p>30s ribosomal subunit (B)</p> Signup and view all the answers

Which of the following types of bacteria are tetracyclines NOT active against?

<p>Mycobacteria (A)</p> Signup and view all the answers

What is the spectrum of activity of tetracyclines?

<p>Broad-spectrum, targeting a wide range of bacterial species (D)</p> Signup and view all the answers

Which type of bacteria are tetracyclines NOT active against? multiple answers

<p>P. aeruginosa (A)</p> Signup and view all the answers

Which of the following bacteria are tetracyclines particularly active against?

<p>Rickettsia spp. (C)</p> Signup and view all the answers

Which bacteria are tetracyclines active against?

<p>spirochetes (A)</p> Signup and view all the answers

What type of bacteria are glycylcyclines like tigecycline active against?

<p>Gram-positive and Gram-negative bacteria (C)</p> Signup and view all the answers

What is tigecycline a derivative of?

<p>Minocycline (A)</p> Signup and view all the answers

Which type of bacteria are glycylcyclines like tigecycline NOT active against? multiple

<p>Staphylococcus spp. (A)</p> Signup and view all the answers

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