Podcast
Questions and Answers
What is the metabolic consequence of ADA deficiency?
What is the metabolic consequence of ADA deficiency?
- Increased conversion of xanthine and guanine to urate
- Inhibition of maturation of T-cells & B-cells (correct)
- Increased purine biosynthesis
- Elevated urate levels
Which enzyme converts Adenosine to Inosine?
Which enzyme converts Adenosine to Inosine?
- Adenosine Deaminase (correct)
- Ribonucleotide Reductase
- Thymidylate Synthase
- Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
What is the consequence of HGPRT deficiency?
What is the consequence of HGPRT deficiency?
- X-linked recessive inheritance
- Gout
- Self-mutilation behavior
- Mental retardation (correct)
Which nucleotide is a powerful antioxidant but can also cause oxidative modifications of proteins and lipids?
Which nucleotide is a powerful antioxidant but can also cause oxidative modifications of proteins and lipids?
"Regulation of Ribonucleotide Reductase" includes inhibition by which molecule?
"Regulation of Ribonucleotide Reductase" includes inhibition by which molecule?
What is the consequence of Uric Acid levels going up due to AMP/GMP catabolism?
What is the consequence of Uric Acid levels going up due to AMP/GMP catabolism?
Which enzyme catalyzes the conversion of UMP to CTP in pyrimidine nucleotide biosynthesis?
Which enzyme catalyzes the conversion of UMP to CTP in pyrimidine nucleotide biosynthesis?
In the reduction of ribonucleotides to deoxyribonucleotides, which enzyme acts on the ribonucleotides?
In the reduction of ribonucleotides to deoxyribonucleotides, which enzyme acts on the ribonucleotides?
Which syndrome is associated with a metabolic basis related to purine and pyrimidine catabolism?
Which syndrome is associated with a metabolic basis related to purine and pyrimidine catabolism?
What are the building blocks of DNA known as?
What are the building blocks of DNA known as?
Which enzyme is responsible for converting aspartate to carbamoylaspartate in pyrimidine nucleotide biosynthesis?
Which enzyme is responsible for converting aspartate to carbamoylaspartate in pyrimidine nucleotide biosynthesis?
Which enzyme catalyzes the conversion of UTP to CTP in pyrimidine nucleotide biosynthesis?
Which enzyme catalyzes the conversion of UTP to CTP in pyrimidine nucleotide biosynthesis?
