Questions and Answers
What is the action of Rho(D) immune globulin (rhogam)?
Prevents formation of anti Rho(D) antibodies.
What is the use of Rho(D) immune globulin (rhogam)?
Helps prevent isoimmunization in Rh negative mothers.
Which of the following are adverse reactions of Rho(D) immune globulin (rhogam)? (Select all that apply)
Which of the following are contraindications for Rho(D) immune globulin (rhogam)? (Select all that apply)
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Rho(D) immune globulin (rhogam) should be administered to the mother by _______ injection at the 28th week of gestation.
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When should Rho(D) immune globulin (rhogam) be administered to the mother after delivery?
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What should be monitored after administering Rho(D) immune globulin (rhogam)?
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Study Notes
Rho(D) Immune Globulin (RhoGAM) Overview
- Rho(D) immune globulin, commonly known as RhoGAM, is a medication that prevents the formation of anti-Rho(D) antibodies.
- Essential for Rh-negative mothers, it helps in avoiding isoimmunization when exposed to Rh-positive red blood cells (RBCs) from the fetus during pregnancy.
Indications for Use
- Administered to Rh-negative pregnant women to prevent complications associated with potential exposure to Rh-positive fetal blood.
- Critical during circumstances like prenatal bleeding, trauma, or after delivery of an Rh-positive infant.
Adverse Reactions
- Possible side effects include elevated body temperature following administration.
- Patients may experience tenderness or discomfort at the injection site.
Contraindications
- Not recommended for Rh-positive women, as it would be ineffective.
- Should be avoided in individuals with a history of systemic allergic reactions to human immunoglobulin preparations.
- Not suitable for administration to newborns.
Administration Guidelines
- Recommended to give an intramuscular injection to the mother during the 28th week of gestation.
- Must also be administered within 72 hours after the delivery of an Rh-positive baby.
- Monitoring the mother's temperature is important following administration to identify any potential adverse effects.
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