Rheology Basics and Applications

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Questions and Answers

Which of the following describes dilatant materials?

  • Their viscosity decreases with increased shear rate.
  • They behave like Newtonian fluids under stress.
  • They exhibit spontaneous deformation upon stress removal.
  • They become thicker or more viscous with increased shear rate. (correct)

What characterizes thixotropic systems?

  • They show an increase in viscosity over time under constant shear.
  • Their viscosity changes instantaneously with shear rate.
  • They become less viscous with sustained shear stress. (correct)
  • They maintain a constant viscosity regardless of shear conditions.

In shear-thinning phenomena, what occurs in a fluid?

  • The fluid remains unchanged regardless of applied shear stress.
  • The viscosity decreases as the shear stress increases. (correct)
  • The viscosity increases in response to higher shear rates.
  • The fluid experiences permanent deformation without recovery.

Which of the following best describes Newtonian fluids?

<p>They have a direct and proportional relationship between shear stress and shear rate. (B)</p> Signup and view all the answers

What type of flow is characterized by the need for a minimum yield stress to begin flowing?

<p>Bingham flow (D)</p> Signup and view all the answers

In non-Newtonian fluids, what happens to the viscosity when shear rates vary?

<p>Viscosity decreases or increases depending on the type of non-Newtonian fluid. (A)</p> Signup and view all the answers

Which condition describes pseudoplastic flow?

<p>Viscosity lowers with increasing shear rate. (D)</p> Signup and view all the answers

Which unit is used to express the coefficient of viscosity?

<p>Centipoise (C)</p> Signup and view all the answers

Which of the following best describes pseudoplastic flow?

<p>The viscosity decreases with increasing shear rates. (C)</p> Signup and view all the answers

What happens to a plastic material when the shear stress is below the yield value?

<p>It behaves like an elastic material. (D)</p> Signup and view all the answers

What characterizes a Newtonian fluid as opposed to a non-Newtonian fluid?

<p>Exhibits constant viscosity irrespective of stress or shear rate. (A)</p> Signup and view all the answers

How is the yield value of a plastic material related to the force of flocculation?

<p>Stronger flocculation leads to higher yield values. (C)</p> Signup and view all the answers

Which equation relates to the plastic viscosity in a Bingham plastic?

<p>$ au = f_B + U D$ (B)</p> Signup and view all the answers

What is the primary effect of shear on pseudoplastic materials at the particulate level?

<p>Molecules align and reduce friction with increased shear. (A)</p> Signup and view all the answers

In dilatant materials, what is the behavior of viscosity as shear rate increases?

<p>Viscosity increases. (A)</p> Signup and view all the answers

What is the primary characteristic of dilatant materials?

<p>They resist stirring or shaking due to caking. (A)</p> Signup and view all the answers

What describes the slope of the rheogram in a plastic material?

<p>Plastic viscosity. (C)</p> Signup and view all the answers

In thixotropic systems, what happens to the structure when shear is applied?

<p>The structure breaks down and viscosity decreases. (C)</p> Signup and view all the answers

Which statement best describes shear-thinning systems?

<p>They have a hysteresis loop in their rheogram. (C)</p> Signup and view all the answers

What does thixotropy specifically refer to?

<p>Slow recovery of consistency after shearing. (C)</p> Signup and view all the answers

What distinguishes non-Newtonian fluids from Newtonian fluids?

<p>Non-Newtonian fluids can show changes in viscosity with varying shear rates. (C)</p> Signup and view all the answers

What happens to an asymmetric particle structure in a thixotropic system at rest?

<p>It conforms to a gel-like state. (B)</p> Signup and view all the answers

What is a common application of thixotropic materials in formulation?

<p>To maintain high consistency while being easy to pour. (C)</p> Signup and view all the answers

What occurs during the flow of a thixotropic material when stress is applied?

<p>The structure becomes aligned and viscosity decreases. (C)</p> Signup and view all the answers

Flashcards

Plastic Flow

A type of non-Newtonian flow where materials don't flow until a certain threshold stress (yield value) is reached, after which they flow linearly.

Yield Value

The minimum stress required to initiate flow in a plastic material.

Bingham Equation

Mathematical equation (τ = fB + μD) that describes plastic flow by relating shear stress (τ), Bingham yield value (fB), plastic viscosity (μ) and shear rate (D).

Pseudoplastic Flow

A type of non-Newtonian flow where the apparent viscosity decreases with increasing shear rate; no yield value.

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Mobility

The slope of the rheogram in plastic flow.

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Plastic Viscosity

The reciprocal of mobility in plastic flow.

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Shear Thinning

Viscosity decreases with increasing shear rate.

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Rheology

The science studying how matter deforms under stress.

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Newtonian Fluid

A fluid where viscosity is constant regardless of the stress applied.

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Non-Newtonian Fluid

A fluid with varying viscosity depending on the stress or flow rate.

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Viscosity

A measure of a fluid's resistance to flow.

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Newton's Law of Viscosity

Stress is directly proportional to the rate of shear.

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Shear Stress

Force per unit area causing deformation in a fluid (N/m2).

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Shear Rate

The rate at which layers of fluid slide past each other (s^-1).

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Thixotropy

A non-Newtonian property where viscosity decreases with shear; returns to original viscosity upon rest.

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Plastic/Bingham Flow

A type of non-Newtonian flow characterized by a yield stress; fluid does not flow until a certain stress is applied.

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Pseudoplastic Flow

A type of Non-Newtonian flow where viscosity decreases as shear rate increases.

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Dilatant Flow

A type of Non-Newtonian flow where viscosity increases as shear rate increases.

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Dilatancy

A property of some suspensions where, when agitated, significant resistance to flow is observed, and the material appears to expand or swell. This occurs as the component settling.

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Deflocculated suspension

A suspension where the particles are not clumped together and the liquid component is able to move easily in between components.

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Flocculated suspension

A suspension where particles are clustered or clumped together.

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Thixotropy

A time-dependent non-Newtonian behavior where viscosity decreases with increasing shear rate, and viscosity increases with decreasing shear rate.

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Newtonian system

A fluid whose viscosity remains constant regardless of the applied shear rate.

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Non-Newtonian system

A fluid whose viscosity changes with the applied shear rate.

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Shear-thinning system

A non-Newtonian fluid whose viscosity decreases as the shear rate increases.

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Rheogram

A graph that shows the relationship between shear stress and shear rate for a fluid.

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Hysteresis loop

A loop in a rheogram where the stress-strain curve for a material during unloading does not follow the loading curve, indicating that some structure is lost that doesn't recover immediately.

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Negative thixotropy (antithixotropy)

A phenomenon where the viscosity of a material increases with time when subjected to shear and shear thinning

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Study Notes

Rheology

  • Rheology is the study of how matter deforms under stress
  • Viscosity measures a fluid's resistance to flow; higher viscosity means greater resistance
  • Stress applied to a system causes strain, which can be elastic (reversible) or viscous (irreversible) or viscoelastic
  • Units of viscosity: centipoise (cP), 1 cP = 1 mPa·s

Newtonian Systems

  • Newtonian fluids have a direct relationship between shear stress and shear rate
  • Newton's Law: Shear rate is directly proportional to shear stress
  • Imagine a fluid as layers; layers slide past each other at progressively decreasing velocity
  • Uppermost layer moves, lower layers move less

Non-Newtonian Systems

  • Most pharmaceutical fluids don't follow Newton's Law, viscosity changes with shear rate
  • Need to measure viscosity over a wide range of shear rates
  • Examples of flow behaviors include plastic, pseudoplastic, and dilatant flows

Plastic Flow

  • Flow starts above a certain yield stress (yield value)
  • Below yield value, material is like an elastic solid
  • Above yield value, material behaves like a Newtonian fluid
  • Viscosity stays constant above the yield value
  • Plastic viscosity: (Shear Stress - Yield Value) / Shear Rate

Pseudoplastic Flow

  • Viscosity decreases as shear rate increases
  • Common in polymer solutions and some natural gums (like tragacanth)

Dilatant Flow

  • Viscosity increases as shear rate increases
  • Suspensions of highly concentrated, small, deflocculated particles
  • Resistance to flow increases with higher shear rate
  • Volume of the material increases with shear

Thixotropy

  • Viscosity decreases with increasing shear rate but recovers over time when shear is reduced
  • Characteristic "downward curve" versus "upward curve" on rheograms
  • Rheology is useful in evaluating how pharmaceutical systems respond to shear

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