Podcast
Questions and Answers
Which of the following describes dilatant materials?
Which of the following describes dilatant materials?
- Their viscosity decreases with increased shear rate.
- They behave like Newtonian fluids under stress.
- They exhibit spontaneous deformation upon stress removal.
- They become thicker or more viscous with increased shear rate. (correct)
What characterizes thixotropic systems?
What characterizes thixotropic systems?
- They show an increase in viscosity over time under constant shear.
- Their viscosity changes instantaneously with shear rate.
- They become less viscous with sustained shear stress. (correct)
- They maintain a constant viscosity regardless of shear conditions.
In shear-thinning phenomena, what occurs in a fluid?
In shear-thinning phenomena, what occurs in a fluid?
- The fluid remains unchanged regardless of applied shear stress.
- The viscosity decreases as the shear stress increases. (correct)
- The viscosity increases in response to higher shear rates.
- The fluid experiences permanent deformation without recovery.
Which of the following best describes Newtonian fluids?
Which of the following best describes Newtonian fluids?
What type of flow is characterized by the need for a minimum yield stress to begin flowing?
What type of flow is characterized by the need for a minimum yield stress to begin flowing?
In non-Newtonian fluids, what happens to the viscosity when shear rates vary?
In non-Newtonian fluids, what happens to the viscosity when shear rates vary?
Which condition describes pseudoplastic flow?
Which condition describes pseudoplastic flow?
Which unit is used to express the coefficient of viscosity?
Which unit is used to express the coefficient of viscosity?
Which of the following best describes pseudoplastic flow?
Which of the following best describes pseudoplastic flow?
What happens to a plastic material when the shear stress is below the yield value?
What happens to a plastic material when the shear stress is below the yield value?
What characterizes a Newtonian fluid as opposed to a non-Newtonian fluid?
What characterizes a Newtonian fluid as opposed to a non-Newtonian fluid?
How is the yield value of a plastic material related to the force of flocculation?
How is the yield value of a plastic material related to the force of flocculation?
Which equation relates to the plastic viscosity in a Bingham plastic?
Which equation relates to the plastic viscosity in a Bingham plastic?
What is the primary effect of shear on pseudoplastic materials at the particulate level?
What is the primary effect of shear on pseudoplastic materials at the particulate level?
In dilatant materials, what is the behavior of viscosity as shear rate increases?
In dilatant materials, what is the behavior of viscosity as shear rate increases?
What is the primary characteristic of dilatant materials?
What is the primary characteristic of dilatant materials?
What describes the slope of the rheogram in a plastic material?
What describes the slope of the rheogram in a plastic material?
In thixotropic systems, what happens to the structure when shear is applied?
In thixotropic systems, what happens to the structure when shear is applied?
Which statement best describes shear-thinning systems?
Which statement best describes shear-thinning systems?
What does thixotropy specifically refer to?
What does thixotropy specifically refer to?
What distinguishes non-Newtonian fluids from Newtonian fluids?
What distinguishes non-Newtonian fluids from Newtonian fluids?
What happens to an asymmetric particle structure in a thixotropic system at rest?
What happens to an asymmetric particle structure in a thixotropic system at rest?
What is a common application of thixotropic materials in formulation?
What is a common application of thixotropic materials in formulation?
What occurs during the flow of a thixotropic material when stress is applied?
What occurs during the flow of a thixotropic material when stress is applied?
Flashcards
Plastic Flow
Plastic Flow
A type of non-Newtonian flow where materials don't flow until a certain threshold stress (yield value) is reached, after which they flow linearly.
Yield Value
Yield Value
The minimum stress required to initiate flow in a plastic material.
Bingham Equation
Bingham Equation
Mathematical equation (τ = fB + μD) that describes plastic flow by relating shear stress (τ), Bingham yield value (fB), plastic viscosity (μ) and shear rate (D).
Pseudoplastic Flow
Pseudoplastic Flow
Signup and view all the flashcards
Mobility
Mobility
Signup and view all the flashcards
Plastic Viscosity
Plastic Viscosity
Signup and view all the flashcards
Shear Thinning
Shear Thinning
Signup and view all the flashcards
Rheology
Rheology
Signup and view all the flashcards
Newtonian Fluid
Newtonian Fluid
Signup and view all the flashcards
Non-Newtonian Fluid
Non-Newtonian Fluid
Signup and view all the flashcards
Viscosity
Viscosity
Signup and view all the flashcards
Newton's Law of Viscosity
Newton's Law of Viscosity
Signup and view all the flashcards
Shear Stress
Shear Stress
Signup and view all the flashcards
Shear Rate
Shear Rate
Signup and view all the flashcards
Thixotropy
Thixotropy
Signup and view all the flashcards
Plastic/Bingham Flow
Plastic/Bingham Flow
Signup and view all the flashcards
Pseudoplastic Flow
Pseudoplastic Flow
Signup and view all the flashcards
Dilatant Flow
Dilatant Flow
Signup and view all the flashcards
Dilatancy
Dilatancy
Signup and view all the flashcards
Deflocculated suspension
Deflocculated suspension
Signup and view all the flashcards
Flocculated suspension
Flocculated suspension
Signup and view all the flashcards
Thixotropy
Thixotropy
Signup and view all the flashcards
Newtonian system
Newtonian system
Signup and view all the flashcards
Non-Newtonian system
Non-Newtonian system
Signup and view all the flashcards
Shear-thinning system
Shear-thinning system
Signup and view all the flashcards
Rheogram
Rheogram
Signup and view all the flashcards
Hysteresis loop
Hysteresis loop
Signup and view all the flashcards
Negative thixotropy (antithixotropy)
Negative thixotropy (antithixotropy)
Signup and view all the flashcards
Study Notes
Rheology
- Rheology is the study of how matter deforms under stress
- Viscosity measures a fluid's resistance to flow; higher viscosity means greater resistance
- Stress applied to a system causes strain, which can be elastic (reversible) or viscous (irreversible) or viscoelastic
- Units of viscosity: centipoise (cP), 1 cP = 1 mPa·s
Newtonian Systems
- Newtonian fluids have a direct relationship between shear stress and shear rate
- Newton's Law: Shear rate is directly proportional to shear stress
- Imagine a fluid as layers; layers slide past each other at progressively decreasing velocity
- Uppermost layer moves, lower layers move less
Non-Newtonian Systems
- Most pharmaceutical fluids don't follow Newton's Law, viscosity changes with shear rate
- Need to measure viscosity over a wide range of shear rates
- Examples of flow behaviors include plastic, pseudoplastic, and dilatant flows
Plastic Flow
- Flow starts above a certain yield stress (yield value)
- Below yield value, material is like an elastic solid
- Above yield value, material behaves like a Newtonian fluid
- Viscosity stays constant above the yield value
- Plastic viscosity: (Shear Stress - Yield Value) / Shear Rate
Pseudoplastic Flow
- Viscosity decreases as shear rate increases
- Common in polymer solutions and some natural gums (like tragacanth)
Dilatant Flow
- Viscosity increases as shear rate increases
- Suspensions of highly concentrated, small, deflocculated particles
- Resistance to flow increases with higher shear rate
- Volume of the material increases with shear
Thixotropy
- Viscosity decreases with increasing shear rate but recovers over time when shear is reduced
- Characteristic "downward curve" versus "upward curve" on rheograms
- Rheology is useful in evaluating how pharmaceutical systems respond to shear
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.