46 Questions
What is the shape of the virions of Rhabdoviruses?
Bullet-shaped
What is the primary reservoir of Rhabdoviruses?
Wild mammals
What is the duration of the incubation period of Rabies?
1 day to years
What is the characteristic inclusion body found in infected neurons in Rabies?
Negri body
What is the form of Rabies that accounts for 80% of patients?
Furious form
What is the approximate number of deaths due to Rabies worldwide?
59,000
What is the estimated percentage of risk reduction through wound cleaning and care for rabies treatment?
90%
What is the primary target of coronaviruses during infection?
Epithelial cells
What is the name of the vaccine used for post-exposure prophylaxis of rabies?
All of the above
What is the typical duration of the incubation period for SARS-CoV-2?
4-5 days
What is the estimated percentage of adults seropositive to common respiratory strains of coronaviruses?
90%
What is the optimal temperature for coronavirus replication?
33-35°C
What is the percentage of hospitalized COVID-19 patients with underlying medical conditions?
90%
What is the name of the virus responsible for Middle East Respiratory Syndrome (MERS)?
MERS-CoV
What is the primary mode of transmission for SARS-CoV-2?
Respiratory secretions
What is the percentage of fatalities among SARS and MERS cases?
9%
What percentage of identified patients experienced fever, cough, or shortness of breath?
70%
What is the mean incubation period of SARS-CoV-2?
4-5 days
What is the percentage of patients who are asymptomatic?
??%
What is the treatment for hospitalized patients requiring supplemental oxygen?
Corticosteroids
What is the name of the vaccine that expressing Spike protein?
mRNA nanoparticles
What is the consequence of rubella infection during the first trimester of pregnancy?
Miscarriage or multiple defects
What is the characteristic of Flaviviruses?
Highly structured 5’ and 3’ UTRs
What is the size of Hepatitis C virus particles?
30-60 nm
What is the error prone feature of Hepatitis C virus polymerase?
Highly error prone
What is the type of endocytosis that Flaviviruses enter via?
Receptor mediated endocytosis
What is the function of NS3 protein in Hepatitis C Virus?
Serine protease required for cleavage of polyprotein
How is Hepatitis C Virus primarily acquired?
Through blood contact, such as blood transfusions and needle sharing
What percentage of people with Hepatitis C Virus will remain infected indefinitely?
75-85%
What is the target of the drug Sofosbuvir?
NS5B polymerase
What is the cost of the 12-week regimen of Glecaprevir-Pibrentasvir?
$26,400
What is the primary mechanism of transmission of Arboviruses?
Vector-borne transmission through arthropods
What is the typical incubation period of Acute Arbovirus Infections?
4-7 days
What is the common complication of Acute Arbovirus Infections?
Viral encephalitis
What is the role of humans in the life cycle of Arboviruses?
All of the above
What is the result of controlling the vector in Arbovirus infections?
Decreased transmission of the virus
What is the primary mode of transmission of Zika virus to humans?
Through the bite of an infected Aedes species mosquito
Which of the following viruses is commonly associated with congenital microcephaly?
Zika virus
What is the typical incubation period for Chikungunya virus?
3-7 days
What is the name of the vaccine used to prevent Dengue fever?
Dengvaxia
Which of the following viruses is carried by Culex mosquitoes?
West Nile virus
What is the main mechanism of error generation during retroviral replication?
Nucleotide misincorporation
What is the estimated percentage of asymptomatic West Nile virus infections?
70-80%
Which of the following viruses is associated with Guillain-Barré syndrome?
Zika virus
What is the primary mechanism of retroviral replication?
Conversion of ssRNA genome to dsDNA
What is the typical duration of symptoms for Chikungunya virus infection?
7-10 days
Test your knowledge on Rhabdoviruses, a family of viruses that includes Rabies, a deadly zoonotic disease transmitted through animal bites. Learn about the characteristics of the virus, its primary reservoirs, and epidemiology.
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