Rhabdoviruses: Rabies and Epidemiology
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Questions and Answers

What is the shape of the virions of Rhabdoviruses?

  • Helical
  • Bullet-shaped (correct)
  • Spherical
  • Fibrous

    • What is the primary reservoir of Rhabdoviruses?

  • Wild mammals (correct)
  • Insects
  • Humans
  • Domestic animals

    • What is the duration of the incubation period of Rabies?

  • 1-7 days
  • 1-90 days
  • 1 day to years (correct)
  • 1-10 years

    • What is the characteristic inclusion body found in infected neurons in Rabies?

    <p>Negri body</p> Signup and view all the answers

    What is the form of Rabies that accounts for 80% of patients?

    <p>Furious form</p> Signup and view all the answers

    What is the approximate number of deaths due to Rabies worldwide?

    <p>59,000</p> Signup and view all the answers

    What is the estimated percentage of risk reduction through wound cleaning and care for rabies treatment?

    <p>90%</p> Signup and view all the answers

    What is the primary target of coronaviruses during infection?

    <p>Epithelial cells</p> Signup and view all the answers

    What is the name of the vaccine used for post-exposure prophylaxis of rabies?

    <p>All of the above</p> Signup and view all the answers

    What is the typical duration of the incubation period for SARS-CoV-2?

    <p>4-5 days</p> Signup and view all the answers

    What is the estimated percentage of adults seropositive to common respiratory strains of coronaviruses?

    <p>90%</p> Signup and view all the answers

    What is the optimal temperature for coronavirus replication?

    <p>33-35°C</p> Signup and view all the answers

    What is the percentage of hospitalized COVID-19 patients with underlying medical conditions?

    <p>90%</p> Signup and view all the answers

    What is the name of the virus responsible for Middle East Respiratory Syndrome (MERS)?

    <p>MERS-CoV</p> Signup and view all the answers

    What is the primary mode of transmission for SARS-CoV-2?

    <p>Respiratory secretions</p> Signup and view all the answers

    What is the percentage of fatalities among SARS and MERS cases?

    <p>9%</p> Signup and view all the answers

    What percentage of identified patients experienced fever, cough, or shortness of breath?

    <p>70%</p> Signup and view all the answers

    What is the mean incubation period of SARS-CoV-2?

    <p>4-5 days</p> Signup and view all the answers

    What is the percentage of patients who are asymptomatic?

    <p>??%</p> Signup and view all the answers

    What is the treatment for hospitalized patients requiring supplemental oxygen?

    <p>Corticosteroids</p> Signup and view all the answers

    What is the name of the vaccine that expressing Spike protein?

    <p>mRNA nanoparticles</p> Signup and view all the answers

    What is the consequence of rubella infection during the first trimester of pregnancy?

    <p>Miscarriage or multiple defects</p> Signup and view all the answers

    What is the characteristic of Flaviviruses?

    <p>Highly structured 5’ and 3’ UTRs</p> Signup and view all the answers

    What is the size of Hepatitis C virus particles?

    <p>30-60 nm</p> Signup and view all the answers

    What is the error prone feature of Hepatitis C virus polymerase?

    <p>Highly error prone</p> Signup and view all the answers

    What is the type of endocytosis that Flaviviruses enter via?

    <p>Receptor mediated endocytosis</p> Signup and view all the answers

    What is the function of NS3 protein in Hepatitis C Virus?

    <p>Serine protease required for cleavage of polyprotein</p> Signup and view all the answers

    How is Hepatitis C Virus primarily acquired?

    <p>Through blood contact, such as blood transfusions and needle sharing</p> Signup and view all the answers

    What percentage of people with Hepatitis C Virus will remain infected indefinitely?

    <p>75-85%</p> Signup and view all the answers

    What is the target of the drug Sofosbuvir?

    <p>NS5B polymerase</p> Signup and view all the answers

    What is the cost of the 12-week regimen of Glecaprevir-Pibrentasvir?

    <p>$26,400</p> Signup and view all the answers

    What is the primary mechanism of transmission of Arboviruses?

    <p>Vector-borne transmission through arthropods</p> Signup and view all the answers

    What is the typical incubation period of Acute Arbovirus Infections?

    <p>4-7 days</p> Signup and view all the answers

    What is the common complication of Acute Arbovirus Infections?

    <p>Viral encephalitis</p> Signup and view all the answers

    What is the role of humans in the life cycle of Arboviruses?

    <p>All of the above</p> Signup and view all the answers

    What is the result of controlling the vector in Arbovirus infections?

    <p>Decreased transmission of the virus</p> Signup and view all the answers

    What is the primary mode of transmission of Zika virus to humans?

    <p>Through the bite of an infected Aedes species mosquito</p> Signup and view all the answers

    Which of the following viruses is commonly associated with congenital microcephaly?

    <p>Zika virus</p> Signup and view all the answers

    What is the typical incubation period for Chikungunya virus?

    <p>3-7 days</p> Signup and view all the answers

    What is the name of the vaccine used to prevent Dengue fever?

    <p>Dengvaxia</p> Signup and view all the answers

    Which of the following viruses is carried by Culex mosquitoes?

    <p>West Nile virus</p> Signup and view all the answers

    What is the main mechanism of error generation during retroviral replication?

    <p>Nucleotide misincorporation</p> Signup and view all the answers

    What is the estimated percentage of asymptomatic West Nile virus infections?

    <p>70-80%</p> Signup and view all the answers

    Which of the following viruses is associated with Guillain-Barré syndrome?

    <p>Zika virus</p> Signup and view all the answers

    What is the primary mechanism of retroviral replication?

    <p>Conversion of ssRNA genome to dsDNA</p> Signup and view all the answers

    What is the typical duration of symptoms for Chikungunya virus infection?

    <p>7-10 days</p> Signup and view all the answers

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