Resting Membrane Potential and Excitable Tissues
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Questions and Answers

What is the typical resting membrane potential (RMP) of a resting neuron?

  • -8.4 mV
  • -53 mV
  • -58 mV
  • -70 mV (correct)

    • What causes the generation of the resting membrane potential (RMP) in a cell?

  • Increased concentration of Na+ inside the cell
  • Nernst potential
  • High concentration of Cl- outside the cell
  • Selective permeability of the cell membrane (correct)

    • Which type of tissues typically have a more negative resting membrane potential (RMP)?

  • Non-excitable tissues
  • RBCs
  • Adipocytes
  • Excitable tissues (correct)

    • What is the role of the Na+ and K+ pump in the generation of resting membrane potential?

    <p>Maintain the ionic distribution across the cell membrane</p> Signup and view all the answers

    What is the main function of the Gibbs’-Donnan equilibrium potential in the genesis of resting membrane potential?

    <p>Equalize the concentrations of intracellular and extracellular ions</p> Signup and view all the answers

    Which ion has a high concentration inside the cell compared to outside?

    <p>Potassium (K+)</p> Signup and view all the answers

    What is the name of the equilibrium established when two solutions containing ions are separated by a membrane?

    <p>Electrochemical equilibrium</p> Signup and view all the answers

    What does the Nernst potential (Equilibrium potential) determine?

    <p>The potential level across the membrane that will exactly prevent net diffusion of an ion</p> Signup and view all the answers

    Which equation is used to calculate the equilibrium potential when the membrane is permeable to several ions?

    <p>Goldman Equation</p> Signup and view all the answers

    What type of channels allow free flow of ions, with a larger number being K+ channels?

    <p>Leaky channels</p> Signup and view all the answers

    What is the net effect of the Na+/K+ pump?

    <p>Causing negative charge inside the membrane</p> Signup and view all the answers

    Which ion contributes more to the resting membrane potential (RMP) according to its efflux potential?

    <p>K+ (Potassium)</p> Signup and view all the answers

    What contributes to the negativity of the resting membrane potential?

    <p>K+ efflux, Na+/K+ pump, and negatively charged protein ions inside the membrane</p> Signup and view all the answers

    What is the main factor contributing to the negativity of the resting membrane potential?

    <p>K+ efflux</p> Signup and view all the answers

    What does the Goldman Equation depend on when calculating the equilibrium potential for multiple ions?

    <p>Polarity of each ion, Membrane permeability, Ionic concentration</p> Signup and view all the answers

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