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Questions and Answers
Which part of the respiratory system allows gas exchange between blood and air?
What is the normal respiratory rate during rest?
Which nerve arises from the cervical neurons and supplies the diaphragm?
Where does gas exchange occur within the respiratory system?
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Which part of the respiratory system has a thick wall and no gas exchange occurs in it?
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In rapid respiration, which characteristic found in normal respiration is absent?
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What is the name of the center in the lower part of the pons that is involved in the cough reflex?
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Which of the following is NOT a medullary center involved in the cough reflex?
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What is the primary function of the cough reflex?
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Where are the receptors for the cough reflex located?
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What is the afferent pathway for the cough reflex?
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What is the stimulus that triggers the cough reflex?
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What happens to the chest diameter when the diaphragm contracts?
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Which muscle contraction is responsible for increasing the anteroposterior and transverse diameters of the chest?
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What is the intrapulmonary pressure reduced to during inhalation?
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What is the process of exhalation primarily driven by?
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In which conditions does deep expiration become an active process?
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Which muscles are considered accessory inspiratory muscles during deep inspiration?
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What is the physiological significance of pulmonary surfactant?
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Which factor accelerates the maturation of surfactant?
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What causes impaired cough reflex according to the text?
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Which condition leads to a serious lung disease due to deficient formation of surfactant?
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How do glucocorticoids affect surfactant maturation?
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What factor decreases lung surfactant according to the text?
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Which of the following is NOT a recommended long-term medication for persistent asthma?
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What is the primary cause of emphysema?
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Which of the following statements about the pathogenesis of emphysema is NOT true?
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What is the primary function of α1-antitrypsin in the lungs?
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Which of the following is a characteristic of emphysema?
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What is the primary goal of patient and family education in asthma management?
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Study Notes
Respiratory System Introduction
- The respiratory system provides a continuous supply of oxygen to the body's tissues and removes carbon dioxide produced by aerobic metabolism.
- The respiratory system consists of the air-conducting part (no gas exchange) and the respiratory part (gas exchange occurs).
- The respiratory part includes respiratory bronchioles, alveolar ducts, and alveoli.
Normal Respiration (Eupnoea)
- Normal respiratory rate: 12-16 cycles per minute.
- Inspiration is an active process, while expiration is a passive process.
- Mechanism of inspiration: signals from the brain stimulate the diaphragm and external intercostal muscles to contract.
Brain Stem Respiratory Centers
- Medullary centers: inspiratory center (dorsal part of medulla oblongata) and expiratory center (ventral part of medulla oblongata).
- Pontine centers: apneustic center (lower pons) and pneumotaxic center (upper pons).
Cough Reflex
- Coughing is a neurally mediated reflex that protects the lungs from secretions and irritating substances.
- Stimulus: irritating substances and excess secretions.
- Response: rapid inspiration, closure of the glottis, and forceful contraction of abdominal and expiratory muscles.
Respiratory Muscles and Mechanism
- Inspiration: diaphragm and external intercostal muscles contract, increasing chest volume and decreasing intrapulmonary pressure.
- Expiration: relaxation of inspiratory muscles, aided by the elastic property of the lung and the weight of the thoracic cage.
- Deep inspiration and expiration: accessory inspiratory and expiratory muscles are activated.
Respiratory Centers and Cough Reflex Impairment
- Respiratory centers control breathing involuntarily.
- Causes of impaired cough reflex: weak abdominal or respiratory muscles, limited chest expansion, disease conditions, and depressed medullary center function.
Surfactant
- Definition: a lipoprotein mixture produced by type II alveolar cells, decreasing surface tension in the alveoli.
- Physiological significance: keeps alveoli open, reduces ventilation effort, and prevents pulmonary edema.
- Factors affecting surfactant: thyroid hormone, glucocorticoids, smoking, insulin, and pulmonary circulation cessation.
Respiratory Distress Syndrome (RDS) and Emphysema
- Respiratory distress syndrome (RDS or hyaline disease): a serious lung disease due to deficient surfactant formation.
- Emphysema: characterized by lung elasticity loss, air space enlargement, and alveolar wall destruction.
- Causes of emphysema: inherited α1-antitrypsin deficiency and smoking.
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Description
Learn about the importance of the respiratory system in providing oxygen to the body's tissues and removing carbon dioxide. Explore the components of the air conducting part and the respiratory part of the respiratory system.