Respiratory System Functions and Anatomy Lab quiz 7

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Questions and Answers

Which of the following mechanisms primarily facilitates the removal of carbon dioxide from the body?

  • Cellular respiration
  • Ventilation (correct)
  • Blood pressure regulation
  • Sound production

How does the respiratory system contribute to maintaining blood pressure?

  • By regulating the pH of the blood via carbon dioxide levels
  • By secreting angiotensin-converting enzyme (ACE) (correct)
  • By directly altering blood volume through excretion of fluids
  • By facilitating gas exchange in the alveoli

If a patient has difficulty swallowing, which anatomical structure of the respiratory system might be impaired?

  • Trachea
  • Epiglottis
  • Pharynx (correct)
  • Larynx

What characteristic of the alveoli's epithelium makes it particularly well-suited for gas exchange?

<p>Simple squamous epithelium (D)</p> Signup and view all the answers

Which of the following best describes the conducting airways as they extend from the bronchi to the bronchioles?

<p>Lose cartilage and gain smooth muscle (D)</p> Signup and view all the answers

According to Boyle's Law, what happens to the pressure within the lungs during inhalation?

<p>It dereases as volume increases (C)</p> Signup and view all the answers

Which muscles are primarily involved in active inspiration?

<p>Diaphragm and external intercostals (B)</p> Signup and view all the answers

Which of the following nervous system components stimulates the diaphragm, leading to its contraction?

<p>Phrenic nerve (B)</p> Signup and view all the answers

What is the primary role of the Dorsal Respiratory Group (DRG) located in the medulla oblongata?

<p>Controls quiet breathing (D)</p> Signup and view all the answers

How is the majority of oxygen transported in the blood?

<p>Bound to hemoglobin in red blood cells (D)</p> Signup and view all the answers

What role does carbonic anhydrase play in carbon dioxide transport?

<p>It facilitates the conversion of carbon dioxide to bicarbonate (A)</p> Signup and view all the answers

What is the effect of the chloride shift on maintaining electrostatic neutrality during carbon dioxide transport?

<p>Chloride ions (Cl-) enter the red blood cells as bicarbonate (HCO3-) exits (A)</p> Signup and view all the answers

What is the approximate value of a normal tidal volume (TV) in a healthy adult?

<p>~500 mL (A)</p> Signup and view all the answers

Which of the following equations correctly defines Inspiratory Capacity (IC)?

<p>IC = TV + IRV (B)</p> Signup and view all the answers

Pulmonary edema primarily affects which aspect of respiratory function?

<p>Diffusion distance (D)</p> Signup and view all the answers

What physiological change is characteristic of emphysema?

<p>Increased lung compliance (C)</p> Signup and view all the answers

Which lung sound is most indicative of fluid in the alveoli?

<p>Crackles (Rales) (B)</p> Signup and view all the answers

What is the primary function of the cilia lining the trachea?

<p>To move mucus and debris upward (B)</p> Signup and view all the answers

During forced expiration, which muscles are actively engaged to reduce lung volume?

<p>Abdominal muscles and internal intercostals (B)</p> Signup and view all the answers

Which of the following respiratory conditions is characterized by reversible airway constriction?

<p>Asthma (A)</p> Signup and view all the answers

How does the contraction of the diaphragm contribute to the process of inspiration?

<p>It increases the volume of the thoracic cavity, leading to decreased pressure. (A)</p> Signup and view all the answers

What is the functional consequence of bronchioles gaining smooth muscle?

<p>Regulation of airflow via bronchoconstriction and bronchodilation. (A)</p> Signup and view all the answers

Which of the following best explains the role of the pneumotaxic center in the pons?

<p>It inhibits the apneustic center, limiting inspiration. (D)</p> Signup and view all the answers

How does the respiratory system contribute to the regulation of blood pH?

<p>By controlling the levels of carbon dioxide in the blood through exhalation. (A)</p> Signup and view all the answers

How does an increase in altitude affect oxygen transport in the blood, and what compensatory mechanism might the body employ?

<p>Decreases oxygen saturation; increased red blood cell production. (D)</p> Signup and view all the answers

Which of the following describes the most significant role of bicarbonate ions ($HCO_3^−$) in carbon dioxide transport?

<p>Conversion of carbon dioxide in plasma, facilitating transport. (C)</p> Signup and view all the answers

How does the anatomical structure of the trachea support its function?

<p>The C-shaped cartilage rings provide flexibility and prevent collapse. (B)</p> Signup and view all the answers

What is the interdependence between tidal volume (TV), inspiratory reserve volume (IRV), and expiratory reserve volume (ERV) in determining vital capacity (VC)?

<p>VC is the sum of TV, IRV, and ERV, representing the total exchangeable air in the lungs. (A)</p> Signup and view all the answers

How might a respiratory therapist use the understanding of lung volumes to assess a patient with restrictive lung disease?

<p>By assessing the total lung capacity to identify reduced lung expansion. (C)</p> Signup and view all the answers

How do conditions like emphysema affect the mechanics of breathing, specifically regarding alveolar function and lung compliance?

<p>Decreased alveolar surface area, increased lung compliance, leading to decreased elasticity. (D)</p> Signup and view all the answers

Which of the following scenarios would most likely result in an increase in the secretion of Angiotensin-Converting Enzyme (ACE)?

<p>A patient experiencing a sudden drop in blood pressure. (B)</p> Signup and view all the answers

In a patient with pulmonary edema, the accumulation of fluid in the alveoli directly impairs which aspect of respiratory function?

<p>The diffusion of gases between the alveoli and the blood. (A)</p> Signup and view all the answers

If a patient is experiencing inflammation of the larynx, which of the following symptoms would you most likely observe?

<p>Loss of voice or hoarseness. (B)</p> Signup and view all the answers

How does the mucociliary escalator, driven by the ciliated epithelium of the trachea, protect the respiratory system?

<p>By trapping and removing debris and pathogens. (C)</p> Signup and view all the answers

During forced expiration, such as when blowing out candles, which muscles are actively involved in decreasing the volume of the thoracic cavity?

<p>Abdominal muscles and internal intercostals. (A)</p> Signup and view all the answers

When auscultating a patient's lungs, you hear crackles (rales). What is the most likely cause of this lung sound?

<p>Fluid in the alveoli. (C)</p> Signup and view all the answers

What type of epithelial tissue is primarily responsible for facilitating gas exchange in the alveoli?

<p>Simple squamous epithelium (D)</p> Signup and view all the answers

According to Boyle's Law, how are pressure and volume related in the context of pulmonary ventilation?

<p>Pressure is inversely proportional to volume; as volume increases, pressure decreases. (B)</p> Signup and view all the answers

A patient is diagnosed with pharyngitis. Which anatomical structure is primarily affected by this condition?

<p>Pharynx (throat) (C)</p> Signup and view all the answers

How does the body maintain electrostatic neutrality during the chloride shift?

<p>By exchanging bicarbonate ions ($HCO_3^−$) for chloride ions ($Cl^−$) across the red blood cell membrane (D)</p> Signup and view all the answers

How does the secretion of Angiotensin-Converting Enzyme (ACE) by the respiratory system contribute to blood pressure regulation?

<p>It converts angiotensin I to angiotensin II, leading to vasoconstriction and increased blood pressure. (C)</p> Signup and view all the answers

What is the functional relationship between the apneustic and pneumotaxic centers located in the pons?

<p>The apneustic center stimulates the DRG, initiating inspiration, while the pneumotaxic center inhibits the apneustic center, limiting inspiration. (D)</p> Signup and view all the answers

How does the anatomical structure of the bronchioles facilitate their function in respiration?

<p>The smooth muscle allows for bronchoconstriction and bronchodilation, regulating airflow to the alveoli. (D)</p> Signup and view all the answers

How does the process of ventilation directly support cellular respiration?

<p>By facilitating the movement of oxygen into the blood and carbon dioxide out of it, ensuring a constant supply of oxygen for cellular respiration and removal of its waste product. (D)</p> Signup and view all the answers

What is the role of carbonic anhydrase in the transport of carbon dioxide ($CO_2$) within the bloodstream?

<p>It catalyzes the conversion of $CO_2$ and water into carbonic acid, which then dissociates into bicarbonate and hydrogen ions. (D)</p> Signup and view all the answers

How does the respiratory system facilitate the excretion of metabolic waste products?

<p>By removing volatile wastes, such as water vapor and carbon dioxide, from the body. (C)</p> Signup and view all the answers

What is the primary function of the epiglottis during the process of swallowing?

<p>To prevent food from entering the trachea by covering the opening of the larynx. (C)</p> Signup and view all the answers

Which of the following best describes the mechanism by which the medulla oblongata regulates respiration during quiet breathing?

<p>The dorsal respiratory group (DRG) controls the basic rhythm of respiration by sending signals to the diaphragm and intercostal muscles. (D)</p> Signup and view all the answers

How does the anatomical arrangement of the trachea, specifically the C-shaped hyaline cartilage rings, support its function?

<p>The rigid cartilage rings prevent the trachea from collapsing during pressure changes that occur during breathing, ensuring an open airway. (A)</p> Signup and view all the answers

During forced expiration, which of the following muscular actions contributes most significantly to decreasing thoracic volume?

<p>Contraction of the abdominal muscles and internal intercostals. (A)</p> Signup and view all the answers

What is the relationship between lung compliance and alveolar structure in a patient with emphysema?

<p>Increased lung compliance due to destruction of alveolar walls and loss of elastic recoil. (A)</p> Signup and view all the answers

How does the respiratory system contribute to maintaining acid-base balance in the body?

<p>By adjusting the rate and depth of breathing to alter the amount of carbon dioxide ($CO_2$) in the blood, which influences blood pH. (C)</p> Signup and view all the answers

A patient presents with inflammation of the pharynx. Which of the following symptoms is most likely to be present?

<p>Difficulty swallowing and a sore throat (A)</p> Signup and view all the answers

How does the chloride shift maintain electrostatic neutrality during carbon dioxide transport?

<p>By exchanging chloride ions ($Cl^−$) for bicarbonate ions ($HCO_3^−$) across the red blood cell membrane. (B)</p> Signup and view all the answers

During auscultation of a patient's lungs, a respiratory therapist hears high-pitched whistling sounds primarily during exhalation. Which condition is most likely indicated by this observation?

<p>Asthma (B)</p> Signup and view all the answers

How does the mucociliary escalator protect the respiratory system from infection and irritation?

<p>By trapping inhaled particles and pathogens in mucus, which is then moved upward by cilia towards the pharynx to be swallowed or expectorated. (D)</p> Signup and view all the answers

What is the effect of an increase in altitude on the oxygen saturation of hemoglobin and what compensatory mechanism might the body employ?

<p>Decreased saturation; increased erythropoietin secretion. (C)</p> Signup and view all the answers

What immediate effect would fluid accumulation in the alveoli, caused by pulmonary edema, elicit on respiratory function?

<p>Decreased diffusion capacity for gases (D)</p> Signup and view all the answers

What is the primary function of Type II alveolar cells in the lungs?

<p>To produce and secrete surfactant, which reduces surface tension in the alveoli. (C)</p> Signup and view all the answers

Which statement accurately describes the interdependence between tidal volume (TV), inspiratory reserve volume (IRV), and expiratory reserve volume (ERV) in determining vital capacity (VC)?

<p>VC represents the maximum amount of air that can be inhaled after a normal exhalation, combining TV, IRV, and ERV. (D)</p> Signup and view all the answers

Flashcards

Gas Exchange

Transfer of oxygen (O2) into blood and removal of carbon dioxide (CO2) from blood.

Cellular Respiration

Oxygen used by mitochondria to generate ATP.

Ventilation

Mechanical movement of air into and out of lungs.

pH Regulation

CO2 levels affect pH; the respiratory system helps regulate pH via exhalation.

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Excretion (Respiratory)

Removes volatile waste like water vapor and CO2.

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Sound Production (Respiratory)

Via larynx (vocal cords).

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Blood Pressure Regulation (Respiratory)

Through secretion of angiotensin-converting enzyme (ACE).

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Nasal Cavity Function

Warms, filters, and humidifies air.

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Pharynx (throat)

Stratified squamous epithelium; passage for food and air.

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Larynx (voice box)

Contains vocal cords; laryngitis = inflammation here.

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Epiglottis

Flap of hyaline cartilage that prevents food from entering the trachea.

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Trachea

Made of C-shaped hyaline cartilage; lined with pseudostratified ciliated columnar epithelium.

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Alveoli

Site of gas exchange; simple squamous epithelium for rapid diffusion.

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Boyle's Law

Pressure is inversely related to volume.

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Inspiration (Active)

Diaphragm and external intercostals contract.

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Expiration (Passive during rest)

Diaphragm and intercostals relax.

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Phrenic Nerve

Stimulates diaphragm

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DRG (Dorsal Respiratory Group)

Controls quiet breathing

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VRG (Ventral Respiratory Group)

Controls forced breathing.

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Tidal Volume (TV)

Normal breath (~500 mL).

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Bronchi to Bronchioles

Conducting airways; bronchioles lose cartilage and gain smooth muscle.

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Cilia in the trachea

Cilia beat to move mucus and debris upward, opposing airflow.

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Apneustic Center

Stimulates DRG, leading to inspiration.

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Pneumotaxic Center

Inhibits apneustic center, leading to expiration.

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Inspiratory Reserve Volume (IRV)

Forced inhale after normal (~3100 mL).

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Expiratory Reserve Volume (ERV)

Forced exhale after normal (~1200 mL)

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Residual Volume (RV)

Air left after max exhale (~1200 mL)

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Vital Capacity (VC)

TV + IRV + ERV

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Inspiratory Capacity (IC)

TV + IRV

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Functional Residual Capacity (FRC)

ERV + RV

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Total Lung Capacity (TLC)

TV + IRV + ERV + RV

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Pharyngitis

Inflammation of pharynx (sore throat).

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Laryngitis

Inflammation of larynx (loss of voice).

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Asthma

Reversible airway constriction.

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COPD

Chronic airflow obstruction (includes emphysema, chronic bronchitis).

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Emphysema

Alveolar destruction, increased compliance.

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Pulmonary Edema

Fluid in alveoli, decreased diffusion distance.

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Wheezes

High-pitched, narrowed airways.

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Stridor

Harsh, upper airway obstruction.

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Crackles (Rales)

Fluid in alveoli.

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Muscles of Forced Inspiration

Sternocleidomastoid, scalenes, and pectoralis major muscles.

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Muscles of Forced Expiration

Abdominal muscles (rectus abdominis, obliques) and internal intercostals.

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Chloride Shift

Maintains electrostatic neutrality as Bicarbonate exits RBC and Chloride enters

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Pleural Friction Rub

Inflamed pleural surfaces rubbing

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Study Notes

Key Functions of the Respiratory System

  • Gas exchange involves transferring oxygen (O₂) into the blood and removing carbon dioxide (CO₂) from the blood
  • Cellular respiration refers to the use of oxygen by mitochondria to produce ATP
  • Ventilation is the mechanical process of moving air into and out of the lungs
  • pH regulation happens because CO₂ levels affect pH; the respiratory system helps regulate pH by exhaling CO₂
  • Excretion removes volatile wastes, such as water vapor and CO₂
  • Sound production occurs via the larynx, specifically the vocal cords
  • Blood pressure regulation happens through the secretion of angiotensin-converting enzyme (ACE)

Respiratory Anatomy and Epithelium

  • The nasal cavity warms, filters, and humidifies air

  • The pharynx (throat) utilizes stratified squamous epithelium, and acts as a passage for both food and air

  • The larynx (voice box) contains vocal cords, with laryngitis referring to inflammation

  • The epiglottis is a flap made of hyaline cartilage that prevents food from entering the trachea

  • The trachea is made of C-shaped hyaline cartilage and lined with pseudostratified ciliated columnar epithelium

  • Cilia beat to move mucus and debris upwards, working against airflow

  • The series of bronchi to bronchioles serve as conducting airways, and the bronchioles lose cartilage while gaining smooth muscle

  • The alveoli are the site of gas exchange and use simple squamous epithelium for rapid diffusion

Mechanics of Breathing

  • Boyle’s Law states that pressure and volume are inversely related

Inspiration (Active)

  • The diaphragm and external intercostals contract during inspiration
  • Volume increases and pressure decreases, resulting in air flowing in

Expiration (Passive during rest)

  • The diaphragm and intercostals relax during expiration
  • Volume decreases and pressure increases, resulting in air flowing out

Forced Breathing

  • Forced inspiration involves the sternocleidomastoid, scalenes, and pectoralis major muscles
  • Forced expiration involves abdominal muscles, like rectus abdominis and obliques, as well as internal intercostals

Nervous System Control

  • The phrenic nerve stimulates the diaphragm
  • The medulla oblongata has two key regions:
  • The Dorsal Respiratory Group (DRG) controls quiet breathing
  • The Ventral Respiratory Group (VRG) controls forced breathing
  • The pons also contains respiratory centers:
  • The Apneustic Center stimulates the DRG, promoting inspiration
  • The Pneumotaxic Center inhibits the apneustic center, promoting expiration

Gas Exchange and Transport

  • Oxygen (O₂) primarily binds to hemoglobin in red blood cells (98%)
  • Some oxygen (2%) dissolves in plasma
  • Carbon dioxide (CO₂) is transported in three ways:
  1. As bicarbonate (HCO₃⁻) – 70% via carbonic anhydrase
  2. Bound to hemoglobin (carbaminohemoglobin) – 23%
  3. Dissolved in plasma – 7%
  • The chloride shift maintains electrostatic neutrality as HCO₃⁻ exits RBCs and Cl⁻ enters

Respiratory Volumes and Capacities

  • Tidal Volume (TV) is the volume of a normal breath, approximately 500 mL
  • Inspiratory Reserve Volume (IRV) is the additional volume from a forced inhale after a normal breath, roughly 3100 mL
  • Expiratory Reserve Volume (ERV) is the additional volume from a forced exhale after a normal breath, about 1200 mL
  • Residual Volume (RV) is the air remaining after a maximal exhale, around 1200 mL

Capacities

  • Vital Capacity (VC) = TV + IRV + ERV
  • Inspiratory Capacity (IC) = TV + IRV
  • Functional Residual Capacity (FRC) = ERV + RV
  • Total Lung Capacity (TLC) = TV + IRV + ERV + RV

Respiratory Conditions

  • Pharyngitis is inflammation of the pharynx, resulting in a sore throat
  • Laryngitis is inflammation of the larynx, leading to loss of voice
  • Asthma is a reversible airway constriction
  • COPD (Chronic Obstructive Pulmonary Disease) is a chronic airflow obstruction, including conditions like emphysema and chronic bronchitis
  • Emphysema involves alveolar destruction and increased compliance
  • Pulmonary Edema refers to fluid in the alveoli, leading to decreased diffusion distance

Auscultation – Lung Sounds

  • Wheezes are high-pitched sounds caused by narrowed airways
  • Stridor is a harsh sound caused by upper airway obstruction
  • Crackles (Rales) are caused by fluid in the alveoli
  • Pleural Friction Rub is a sound caused by inflamed pleural surfaces rubbing together

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