Respiratory Physiology Quiz
68 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which muscle is NOT involved in forced inhalation?

  • Scalenes
  • Sternocleidomastoids
  • Diaphragm (correct)
  • Pectoralis Minor
  • Quiet expiration is a passive process because:

  • The diaphragm contracts to force air out of the lungs.
  • The relaxation of the diaphragm allows for a decrease in lung volume. (correct)
  • The diaphragm remains contracted during quiet expiration.
  • The intercostal muscles contract to push air out of the lungs.
  • Which condition is NOT directly associated with Type 1 Respiratory Failure?

  • Pulmonary Embolism
  • Kidney Failure (correct)
  • Pneumonia
  • Asthma
  • During external respiration, the primary exchange of gases occurs between:

    <p>Blood and the alveoli (D)</p> Signup and view all the answers

    What is the normal partial pressure of oxygen (PaO2) in the alveolar space?

    <p>100 mmHg (B)</p> Signup and view all the answers

    What is the primary function of the accessory muscles of inspiration?

    <p>To assist in forced inhalation. (D)</p> Signup and view all the answers

    Which scenario reflects a ventilation-perfusion (V/Q) mismatch?

    <p>When the amount of air reaching the alveoli is less than the amount of blood flow in the capillaries. (A)</p> Signup and view all the answers

    Which of the following is NOT a potential cause of Type 1 Respiratory Failure?

    <p>Kidney Stones (D)</p> Signup and view all the answers

    What is the primary function of the diaphragm in breathing?

    <p>To expand the chest cavity during inspiration. (C)</p> Signup and view all the answers

    What is the term for the exchange of gases between blood and cells?

    <p>Internal Respiration (C)</p> Signup and view all the answers

    Which of the following is NOT a function of the paranasal sinuses?

    <p>Provides airway for respiration (D)</p> Signup and view all the answers

    What is the primary function of the epiglottis during respiration?

    <p>Preventing food or fluids from entering the lungs (B)</p> Signup and view all the answers

    Which of the following structures is responsible for the production of surfactant?

    <p>Type II cells (B)</p> Signup and view all the answers

    What is the function of the cilia in the bronchi and bronchioles?

    <p>Removal of contaminants (C)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding the differences between the right and left lungs?

    <p>The right lung has 3 lobes, while the left has 2. (A)</p> Signup and view all the answers

    Which of the following describes the correct order of structures through which air travels from the nasal cavity to the alveoli?

    <p>Nasopharynx → Oropharynx → Laryngopharynx → Trachea → Bronchi → Bronchioles → Alveoli (C)</p> Signup and view all the answers

    What is the role of the visceral pleura in the respiratory system?

    <p>Covers the outer surface of the lungs (B)</p> Signup and view all the answers

    What is the main function of the alveolar macrophages?

    <p>To remove foreign particles and debris from the alveoli and bronchioles (D)</p> Signup and view all the answers

    How would you explain the process of gas exchange in the alveoli?

    <p>Oxygen diffuses from the alveoli into the blood, while carbon dioxide diffuses from the blood into the alveoli. (B)</p> Signup and view all the answers

    Which of the following conditions would most likely affect the respiratory membrane and gas exchange?

    <p>All of the above (D)</p> Signup and view all the answers

    What are the consequences of poor compliance of the alveoli?

    <p>Increased difficulty in inflating the lungs during inhalation (B)</p> Signup and view all the answers

    Which of the following is NOT a component of the conducting system?

    <p>Alveolar ducts (A)</p> Signup and view all the answers

    What is the primary function of the pulmonary vessels?

    <p>Facilitating gas exchange between the blood and the alveoli (C)</p> Signup and view all the answers

    What is the role of the bronchial vessels?

    <p>Supplying oxygenated blood to the lung tissues (A)</p> Signup and view all the answers

    Which of the following is NOT a component of the respiratory zone?

    <p>Terminal bronchioles (D)</p> Signup and view all the answers

    What is the main cause of COPD deaths?

    <p>Continued smoking or exposure (B)</p> Signup and view all the answers

    What is the main enzyme responsible for proteolysis in the lungs?

    <p>Elastase (B)</p> Signup and view all the answers

    Which of these symptoms is NOT associated with emphysema?

    <p>Chronic productive cough (D)</p> Signup and view all the answers

    What is the main pathological change in the lungs of an emphysema patient?

    <p>Alveolar wall destruction (A)</p> Signup and view all the answers

    Which of these is NOT a common complication of COPD?

    <p>Asthma exacerbation (D)</p> Signup and view all the answers

    What is the correct definition of status asthmaticus?

    <p>A life-threatening condition requiring immediate medical attention (B)</p> Signup and view all the answers

    What is the term used for the condition where the airway collapses due to loss of lung recoil?

    <p>Emphysema (A)</p> Signup and view all the answers

    Which of these is NOT a risk factor for COPD?

    <p>Low levels of Alpha-1-antitrypsin (A)</p> Signup and view all the answers

    What is the main reason for the increased mortality related to COPD?

    <p>Continued smoking or exposure (C)</p> Signup and view all the answers

    What is the term used for the increased sensitivity to bronchoprovocation testing in COPD patients?

    <p>Bronchial hyperresponsiveness (D)</p> Signup and view all the answers

    What is the main difference between 'pink puffers' and 'blue bloaters' in COPD?

    <p>Pink puffers have emphysema, blue bloaters have chronic bronchitis (C)</p> Signup and view all the answers

    Which of these is NOT a pathological change associated with chronic bronchitis?

    <p>Alveolar wall destruction (B)</p> Signup and view all the answers

    What is the main function of Alpha-1-antitrypsin?

    <p>To inhibit the activity of elastase (D)</p> Signup and view all the answers

    Which of these is NOT a clinical presentation of COPD?

    <p>Presence of repeatable triggers (A)</p> Signup and view all the answers

    What is the main pathophysiological mechanism behind COPD?

    <p>Inflammation and narrowing of the airways (C)</p> Signup and view all the answers

    Which of the following is a genetic polymorphism associated with an increased risk of COPD?

    <p>Increased MMPs (A)</p> Signup and view all the answers

    Which factor is NOT associated with the etiology of asthma during childhood?

    <p>Prenatal exposure to maternal smoking (A)</p> Signup and view all the answers

    What is a hallmark of asthma pathology?

    <p>Bronchial hyper-reactivity (A)</p> Signup and view all the answers

    Which mediator is released by mast cells during the allergen-induced bronchoconstriction?

    <p>Histamine (A)</p> Signup and view all the answers

    What triggers the release of inflammatory cells in the late-phase reaction of bronchial inflammation?

    <p>Cytokines and TNF-a (B)</p> Signup and view all the answers

    Which of the following factors is classified as not related to occupational exposures?

    <p>Respiratory syncytial virus (B)</p> Signup and view all the answers

    How does airway remodeling in asthma progress?

    <p>It is permanent (A)</p> Signup and view all the answers

    What role do Th2 cells play in asthma?

    <p>Regulating IgE production (B)</p> Signup and view all the answers

    Which environmental exposure is recognized as a factor contributing to asthma in adulthood?

    <p>Tobacco smoke (A)</p> Signup and view all the answers

    What is a mechanism through which bronchoconstriction occurs?

    <p>Release of acetylcholine (B)</p> Signup and view all the answers

    Which of the following is considered an asthma trigger?

    <p>Cold air (C)</p> Signup and view all the answers

    What is the primary function of the peak-flow meter?

    <p>To monitor changes in lung function over time in people with asthma. (A)</p> Signup and view all the answers

    Which of the following is NOT a lung volume measured by spirometry?

    <p>Forced Expiratory Volume in 1 second (FEV1) (D)</p> Signup and view all the answers

    Which lung function index is most helpful in differentiating between obstructive and restrictive lung disease?

    <p>FEV1 / FVC ratio (D)</p> Signup and view all the answers

    Which of these is NOT a characteristic of asthma?

    <p>Progressive lung fibrosis (D)</p> Signup and view all the answers

    What is the primary reason why people who smoke have poor exercise tolerance?

    <p>All of the above. (D)</p> Signup and view all the answers

    Which of the following is NOT a maternal factor associated with asthma risk in children?

    <p>Exposure to allergens during pregnancy (C)</p> Signup and view all the answers

    Which of the following is a primary component of the Hygiene Hypothesis?

    <p>Early exposure to bacteria and endotoxins may protect against asthma development. (D)</p> Signup and view all the answers

    Which of the following is a common allergen associated with asthma?

    <p>Pollen (C)</p> Signup and view all the answers

    How does aging affect lung function?

    <p>Respiratory tissues and chest wall become more rigid, leading to a decrease in vital capacity. (A)</p> Signup and view all the answers

    What is the primary function of the diaphragm in respiration?

    <p>To contract and expand the chest cavity, aiding in inhalation and exhalation. (A)</p> Signup and view all the answers

    What is the primary effect of a bronchodilator on the airways?

    <p>To relax smooth muscle in the airways, widening them. (A)</p> Signup and view all the answers

    What is the main difference between acute and chronic compensation in acid-base balance?

    <p>Acute compensation occurs rapidly, while chronic compensation is slower and more sustained. (C)</p> Signup and view all the answers

    What is the role of the kidneys in metabolic compensation of acid-base balance?

    <p>To reabsorb or excrete bicarbonate (HCO3-) from the blood. (A)</p> Signup and view all the answers

    Which of the following is a common symptom of asthma?

    <p>Persistent cough (D)</p> Signup and view all the answers

    What does 'airway hyper-responsiveness' mean in the context of asthma?

    <p>The airways become overly sensitive to various triggers, leading to narrowing. (D)</p> Signup and view all the answers

    Which of the following is a potential benefit of exposure to endotoxin in early childhood?

    <p>It can strengthen the immune system and reduce the likelihood of asthma. (D)</p> Signup and view all the answers

    What is the role of cilia in the respiratory system?

    <p>To trap foreign particles and move them out of the airways. (B)</p> Signup and view all the answers

    Flashcards

    Nose and nasal cavity

    Provides airway for respiration, moistens and filters air, contains olfactory receptors.

    Paranasal sinuses

    Air-containing cavities in the skull lined with mucous membrane, decreases skull weight and increases voice resonance.

    Pharynx

    Upper part of the throat that serves as an air and food passageway, divided into nasopharynx, oropharynx, and laryngopharynx.

    Larynx

    Connects the pharynx to the trachea, contains vocal cords and roles in protection and coughing.

    Signup and view all the flashcards

    Trachea

    The windpipe that connects the larynx to the bronchi, allowing air passage to the lungs.

    Signup and view all the flashcards

    Bronchi

    Branches of the trachea that lead to the lungs, containing mucus and cilia for filtering air.

    Signup and view all the flashcards

    Lungs

    Organs containing lobes for gas exchange, right lung has 3 lobes, left has 2, covered by pleura.

    Signup and view all the flashcards

    Alveoli

    Tiny air sacs in the lungs where gas exchange occurs, surrounded by capillaries.

    Signup and view all the flashcards

    Type I cells

    Squamous epithelial cells in alveoli, facilitating gas exchange.

    Signup and view all the flashcards

    Type II cells

    Cuboidal epithelial cells in alveoli that secrete surfactant to reduce surface tension.

    Signup and view all the flashcards

    Lung compliance

    The ability of the lungs/alveoli to expand during inhalation.

    Signup and view all the flashcards

    Pulmonary vessels

    Blood vessels responsible for transporting deoxygenated blood to the lungs for oxygenation.

    Signup and view all the flashcards

    Conducting system

    Pathways that conduct air into the lungs, from nose to bronchioles.

    Signup and view all the flashcards

    Respiration

    The process of gas exchange between the atmosphere, blood, and cells.

    Signup and view all the flashcards

    Pulmonary ventilation

    The process of moving air into and out of the lungs.

    Signup and view all the flashcards

    Quiet inspiration

    An active process of normal breathing involving diaphragm and intercostal muscles.

    Signup and view all the flashcards

    Forced inspiration

    Enhanced breathing using additional muscles (sternocleidomastoids, scalenes) during high demand.

    Signup and view all the flashcards

    Quiet expiration

    A passive process where the diaphragm relaxes and rises, allowing air to exit.

    Signup and view all the flashcards

    Forced expiration

    Active contraction of muscles to expel air quickly, used when airflow is obstructed.

    Signup and view all the flashcards

    External respiration

    Gas exchange between air and blood in the alveoli; O2 taken in, CO2 released.

    Signup and view all the flashcards

    V/Q mismatch

    An imbalance between ventilation and perfusion leading to inadequate gas exchange and hypoxemia.

    Signup and view all the flashcards

    Internal respiration

    Gas exchange between blood and tissues; oxygen enters cells while carbon dioxide leaves.

    Signup and view all the flashcards

    Low Omega-3

    A dietary deficiency linked to several health issues, including asthma.

    Signup and view all the flashcards

    Maternal Smoking

    Exposure to maternal smoking during pregnancy can increase asthma risk in children.

    Signup and view all the flashcards

    Pre-eclampsia

    A pregnancy complication characterized by high blood pressure and can influence asthma risk.

    Signup and view all the flashcards

    Childhood Infections

    Certain viral infections in childhood, like RSV and HRV, are predictive of asthma later in life.

    Signup and view all the flashcards

    Tobacco Smoke Exposure

    Contact with tobacco smoke, either first or second-hand, increases asthma risk during adulthood.

    Signup and view all the flashcards

    Obesity and Asthma

    Excess body weight contributes to the development and exacerbation of asthma symptoms.

    Signup and view all the flashcards

    Asthma Triggers

    Factors like irritants, infections, and weather changes that can provoke asthma symptoms.

    Signup and view all the flashcards

    Bronchial Hyper-reactivity

    An exaggerated response of the airways to various stimuli, a key feature in asthma.

    Signup and view all the flashcards

    Airway Remodeling

    Irreversible changes in the airway structure due to chronic inflammation from asthma.

    Signup and view all the flashcards

    Mast Cell Mediators

    Substances released by mast cells during an asthma attack, leading to bronchoconstriction.

    Signup and view all the flashcards

    PaCO2

    Pressure exerted by dissolved CO2 in blood.

    Signup and view all the flashcards

    PaO2

    Level of oxygenation in arterial blood.

    Signup and view all the flashcards

    Metabolic Disorder

    Disorder from altered HCO3, influenced by kidneys.

    Signup and view all the flashcards

    Respiratory Disorder

    Disorder from altered CO2 levels, influenced by lungs.

    Signup and view all the flashcards

    Respiratory Compensation

    Lungs adjust CO2 retention/excretion to balance pH.

    Signup and view all the flashcards

    Metabolic Compensation

    Kidneys adjust HCO3 retention/excretion for pH balance.

    Signup and view all the flashcards

    Spirometry

    Test to assess pulmonary performance by measuring airflow.

    Signup and view all the flashcards

    Peak-flow Meter

    Used by asthmatics to monitor breathing capacity.

    Signup and view all the flashcards

    FEV1/FVC Ratio

    Helps differentiate between restrictive and obstructive lung diseases.

    Signup and view all the flashcards

    Obstructive Lung Disease

    Characterized by low FEV1/FVC ratio and normal FVC.

    Signup and view all the flashcards

    Restrictive Lung Disease

    Normal FEV1/FVC ratio with low FVC.

    Signup and view all the flashcards

    Asthma

    Chronic inflammatory disorder causing wheezing and dyspnea.

    Signup and view all the flashcards

    Genetic Predisposition

    Influence of genes on development and severity of asthma.

    Signup and view all the flashcards

    Hygiene Hypothesis

    Limited exposure to infections may increase allergy development.

    Signup and view all the flashcards

    Atopic vs Non-Atopic

    Atopic individuals have allergic responses leading to asthma.

    Signup and view all the flashcards

    COPD

    Chronic obstructive pulmonary disease, characterized by persistent respiratory symptoms and airflow limitation.

    Signup and view all the flashcards

    Status asthmaticus

    A severe asthma exacerbation that is unresponsive to standard treatments, requiring intensive management.

    Signup and view all the flashcards

    Emphysema

    A type of COPD marked by destruction of alveolar walls, leading to loss of lung elasticity and air trapping.

    Signup and view all the flashcards

    Chronic bronchitis

    A type of COPD characterized by chronic cough and mucus production due to inflammation of the bronchi.

    Signup and view all the flashcards

    Hypoxemia

    Low levels of oxygen in the blood, often seen in severe respiratory conditions.

    Signup and view all the flashcards

    Mucociliary dysfunction

    Impaired function of the cilia and mucus in clearing airways, common in chronic lung diseases.

    Signup and view all the flashcards

    Airflow limitation

    Reduced ability to expel air from the lungs, characteristic of COPD.

    Signup and view all the flashcards

    Cough and dyspnea

    Persistent cough and shortness of breath, key symptoms of many chronic lung diseases.

    Signup and view all the flashcards

    Bronchodilator

    A medication that relaxes and opens the airways, commonly used in asthma and COPD treatment.

    Signup and view all the flashcards

    Inflammatory cell infiltration

    Accumulation of immune cells in the lungs during chronic lung inflammation.

    Signup and view all the flashcards

    Atopy

    Genetic tendency to develop allergic diseases like asthma and eczema, often linked to environmental triggers.

    Signup and view all the flashcards

    Hypercapnia

    Elevated carbon dioxide levels in the blood, often due to hypoventilation or severe respiratory conditions.

    Signup and view all the flashcards

    Study Notes

    Respiratory System Anatomy

    • The upper respiratory tract includes the nose, nasal cavity, paranasal sinuses, pharynx, and larynx
    • The nose and nasal cavity provide an airway for respiration, moisten and warm air, filter inhaled air, and contain olfactory receptors. They are also involved in speech.
    • Paranasal sinuses are air-containing cavities in the skull lined with mucous membrane. Possible functions include decreasing skull weight, increasing voice resonance, buffering against facial trauma, insulating sensitive structures, humidifying and heating air, and supporting immunological defense.
    • The pharynx is the upper part of the throat. It has three sections: nasopharynx (air passageway), oropharynx (food and air passageway), and laryngopharynx (connects throat to esophagus). It includes tonsils (nasopharyngeal and palatine/lingual).
    • The larynx connects the laryngopharynx to the trachea and contains vocal folds. The thyroid gland sits on the outside of the larynx. The larynx's main function is protective, aiding in coughing and preventing food/fluid from entering the lungs.
    • The lower respiratory tract includes the trachea, bronchi (and smaller bronchioles), lungs, and alveoli.

    Respiratory System Physiology

    • Respiration exchanges gases between the atmosphere, blood, and cells
    • Components include pulmonary ventilation (breathing), external respiration (gas exchange between air and blood), and internal respiration (gas exchange between blood and cells)

    Pulmonary Ventilation

    • Inspiration (breathing in) occurs when alveolar pressure is less than atmospheric pressure. The diaphragm and external intercostal muscles contract, expanding the thoracic cavity. Forced inspiration utilizes accessory muscles.
    • Expiration (breathing out) is a passive process. The diaphragm relaxes, and the thoracic cavity contracts causing air pressure to rise above atmospheric pressure, forcing air out. Forced expiration uses the abdominal muscles.

    External Respiration

    • External respiration is the exchange of gases between the air and blood in the alveoli and capillaries. Oxygen diffuses from the alveoli into the blood. Carbon dioxide diffuses from the blood into the alveoli.
    • This process is driven by differences in partial pressures; normal partial pressure of oxygen (paO2) gradient: alveolar space= 100 mmHg, deoxygenated blood = 40 mmHg. Normal partial pressure of carbon dioxide (paCO2) gradient: alveolar space= 40 mmHg, deoxygenated blood = 45 mmHg.

    Ventilation-Perfusion Matching

    • Ventilation-perfusion matching is the balance of air flow into the alveoli and blood flow through the capillaries to facilitate external respiration.
    • The ratio of ventilation (V) and perfusion (Q) must be balanced (approximately 0.8) for gas exchange. Disruptions (abnormal V/Q ratios) lead to hypoxemia (low blood oxygen).

    Internal Respiration

    • Internal respiration facilitates the exchange of oxygen and carbon dioxide between blood and the body’s cells. Oxygen diffuses from the blood into the cells. Carbon dioxide diffuses from the cells into the blood.

    Type 1 and Type 2 Respiratory Failure

    • Type 1 respiratory failure is characterized by the inability of the lungs to effectively exchange gases. It results in hypoxemia. Common causes include: lung disorders (asthma, COPD), pneumonia, pulmonary edema, fibrosis, and embolism.
    • Type 2 respiratory failure involves the body's inability to effectively remove carbon dioxide. It results in hypercapnia. Potential causes include impaired CNS function, neuromuscular impairment, chronic bronchitis or COPD, and excessive inspiratory load. Both types can lead to complications if not treated promptly

    Acid-Base Balance

    • Arterial blood gases measure acid-base balance, aiding in determining the cause of respiratory issues. Blood pH is regulated by the lungs and kidneys.
    • Compensation may occur by adjusting retention or excretion of CO2 (respiratory) and HCO3 (metabolic). The time course of compensation (acute vs. chronic) affects risk.

    Lung Function Testing

    • Spirometry measures lung function including lung volumes (Tidal Volume, Inspiratory Reserve Volume, Expiratory Reserve Volume, Residual Volume) and lung capacities (Total Lung Capacity, Functional Residual Capacity, Vital Capacity). Airflow measures, like FEV1/FVC ratio, differentiate between obstructive and restrictive lung disease.
    • Peak flow meters aid in self-monitoring of lung function, particularly helpful for asthma patients. Spirometry to determine reversibility of airway obstruction is conducted by repeating the test 10-15 minutes after inhaling a bronchodilator. An increase in FEV1 indicates airway obstruction.

    Effect of Fitness and Aging on the Respiratory System

    • Proper respiratory function requires a strong cardiovascular system
    • Exercise increases blood flow and oxygen consumption.
    • Fitness improves lung capacity, gas diffusion, and strengthens respiratory muscles.
    • Aging affects lung function through decreased lung compliance and weakened respiratory muscles. Smokers exhibit decreased exercise tolerance due to factors like nicotine-induced bronchoconstriction, lung fibrosis, excess mucus, cilia inhibition, and elastic fiber destruction

    Asthma

    • Asthma is a chronic inflammatory disorder marked by intermittent episodes of wheezing, coughing, and dyspnea, often worse at night or upon waking. Symptoms are associated with airway hyper-responsiveness.
    • Possible diagnostic factors include: FEV1/FVC <0.7, significant reversibility post-bronchodilator challenge (>+12%), and sensitivity to broncho-provocation testing.
    • Asthma exacerbations (status asthmaticus) can be life-threatening.
    • Etiology and Risk factors includes: genetics, hygiene hypothesis, sex, maternal factors (pregnancy, smoking), perinatal factors, environmental factors (childhood, adulthood), and triggers.

    COPD

    • COPD (Chronic Obstructive Pulmonary Disease) is a chronic respiratory disease characterized by persistent symptoms, airflow limitation, chronic inflammation, and mucociliary dysfunction. Often a mix of emphysema and chronic bronchitis.
    • COPD is associated with cigarette smoking, air pollutants, airway reactivity and genetic polymorphisms (Alpha-1 antitrypsin deficiency).
    • Pathophysiology of emphysema includes imbalances in proteolytic and anti-proteolytic factors causing alveolar wall destruction and impaired lung recoil. In chronic bronchitis, chronic inflammation leads to mucus hypersecretion, ciliary dysfunction, and airway obstruction.

    Treatment

    • Asthma treatments often focus on relievers (SABA, SAMA, theophylline) and controllers (ICS, LABA). Biologics are reserved for severe cases.
    • COPD treatments generally use the same short and long-acting beta-adrenergic agonists, long and short-acting antimuscarinics, and in some cases inhaled corticosteroids.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Description

    Test your knowledge on respiratory physiology with this quiz covering key concepts such as forced inhalation, gas exchange, and the functions of various respiratory structures. Questions explore conditions related to respiratory failure and the role of muscles in breathing. Perfect for students studying human biology or related fields.

    More Like This

    Respiratory Physiology Overview
    9 questions

    Respiratory Physiology Overview

    CongenialMoldavite4557 avatar
    CongenialMoldavite4557
    Respiratory Physiology Overview
    30 questions
    Use Quizgecko on...
    Browser
    Browser