Respiratory Module Session 3

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Questions and Answers

What is the function of pleural fluid?

  • To hold the lungs in place within the chest cavity
  • To allow for efficient gas exchange between the lungs and the blood
  • To provide structural support to the chest wall
  • To lubricate the pleural membranes and prevent friction during breathing (correct)

What happens to the volume of the lungs when the volume of the thoracic cage changes?

  • The volume of the lungs changes inversely to the volume of the thoracic cage.
  • The volume of the lungs increases when the thoracic cage expands. (correct)
  • The volume of the lungs remains constant, regardless of changes in the thoracic cage.
  • The volume of the lungs decreases when the thoracic cage contracts. (correct)

What is the main muscle responsible for inspiration during quiet breathing?

  • External intercostal muscles
  • Diaphragm (correct)
  • Sternocleidomastoid muscles
  • Scalene muscles

Which of the following is not an accessory muscle of inspiration?

<p>Rectus abdominis (C)</p> Signup and view all the answers

How does deep inspiration differ from quiet inspiration?

<p>It involves contraction of accessory muscles of inspiration (C)</p> Signup and view all the answers

Which of the following factors influences airway resistance during breathing?

<p>The diameter of the airways (A)</p> Signup and view all the answers

What happens to airway resistance during the breathing cycle?

<p>Airway resistance is lower during inspiration and higher during expiration (D)</p> Signup and view all the answers

What is the primary force driving expiration during quiet breathing?

<p>Elastic recoil of the lungs (B)</p> Signup and view all the answers

During normal, quiet breathing, what is the primary force responsible for expiration?

<p>Elastic recoil of the lungs (A)</p> Signup and view all the answers

Which of the following muscles are involved in forced expiration?

<p>Internal intercostal muscles (C)</p> Signup and view all the answers

What is the typical respiratory rate for a healthy individual?

<p>12-16 cycles/minute (A)</p> Signup and view all the answers

What is the term for the ability of the lung to stretch?

<p>Compliance (D)</p> Signup and view all the answers

What is the correct definition of lung compliance?

<p>The volume change per unit pressure change (C)</p> Signup and view all the answers

Which of the following statements about the diaphragm is TRUE?

<p>It is responsible for 75% of inspiration. (A)</p> Signup and view all the answers

How does the contraction of the abdominal muscles influence expiration?

<p>It increases the pressure inside the abdominal cavity, pushing the diaphragm upwards. (B)</p> Signup and view all the answers

What is the primary function of the internal intercostal muscles?

<p>To contract and decrease the chest cavity during forced expiration. (C)</p> Signup and view all the answers

What effect does surfactant have on the force required to expand small alveoli compared to large ones?

<p>It decreases the force required for small alveoli. (A)</p> Signup and view all the answers

What would happen to the alveoli if the surface tension remained constant and the alveoli varied in size?

<p>The smaller alveoli would collapse into the larger ones. (B)</p> Signup and view all the answers

What is the relationship between the radius of an alveolus and the surface tension in the alveolus?

<p>As the radius increases, the surface tension decreases. (A)</p> Signup and view all the answers

What is the primary function of surfactant in the lungs?

<p>To prevent the collapse of small alveoli. (C)</p> Signup and view all the answers

What is the term for the condition that occurs when surfactant is absent from the alveoli of a premature baby?

<p>Respiratory Distress Syndrome (B)</p> Signup and view all the answers

Which of the following is NOT a function of surfactant?

<p>Increases the surface tension in alveoli. (C)</p> Signup and view all the answers

What type of cells produce surfactant?

<p>Type II alveolar cells (D)</p> Signup and view all the answers

What is the primary component of surfactant?

<p>Phospholipids (C)</p> Signup and view all the answers

According to the Law of Laplace, what is the relationship between pressure within an alveolus and the radius of the alveolus?

<p>Pressure is inversely proportional to the radius of the alveolus. (D)</p> Signup and view all the answers

What is the effect of surfactant on surface tension as an alveolus shrinks?

<p>Surfactant decreases surface tension as the alveolus shrinks. (A)</p> Signup and view all the answers

What is the primary factor that determines the resistance of an airway to flow?

<p>The radius of the airway. (C)</p> Signup and view all the answers

Why is the combined resistance of the small airways normally low?

<p>Because they are connected in parallel. (A)</p> Signup and view all the answers

What is the effect of surfactant on the stability of the alveoli?

<p>Surfactant makes the alveoli more stable. (B)</p> Signup and view all the answers

What is the role of hydrogen bonding in the function of surfactant?

<p>Hydrogen bonding makes surfactant less effective in reducing surface tension. (A)</p> Signup and view all the answers

What is the primary location of airway resistance in the normal lung?

<p>Upper respiratory tract. (B)</p> Signup and view all the answers

What is the disorder associated with decreased surfactant production?

<p>Acute respiratory distress syndrome (ARDS). (A)</p> Signup and view all the answers

What is the primary reason for the increased compliance of the lungs in Chronic Obstructive Pulmonary Disease (COPD)?

<p>Degeneration of the alveolar walls. (D)</p> Signup and view all the answers

Which of the following scenarios can lead to a DECREASE in lung compliance?

<p>Alveolar edema. (B)</p> Signup and view all the answers

Why does the compliance of the lungs decrease at high lung volumes?

<p>The chest wall reaches its limit of expansion. (A)</p> Signup and view all the answers

What is the role of surfactant in the lungs?

<p>To decrease the surface tension of the alveolar fluid. (C)</p> Signup and view all the answers

Which of the following statements accurately describes the relationship between lung compliance and surfactant?

<p>As surfactant concentration decreases, lung compliance decreases. (A)</p> Signup and view all the answers

What is the relationship between compliance and the work of breathing?

<p>Higher compliance means less work of breathing. (C)</p> Signup and view all the answers

What is the primary contributor to the elastic properties of the lungs?

<p>Both A and B. (D)</p> Signup and view all the answers

Why is a healthy lung's compliance typically low at low lung volumes?

<p>The surface tension of the alveolar fluid is very high. (A)</p> Signup and view all the answers

Flashcards

Diaphragm Function

The diaphragm is responsible for 75% of inspiration during breathing.

External Intercostal Muscles

These muscles can aid inspiration if the diaphragm is paralyzed during moderate activity.

Resting Expiratory Level

The equilibrium position at the end of normal expiration with relaxed respiratory muscles.

Passive Expiration

Expiration occurs passively due to the elastic recoil of the lungs during quiet breathing.

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Forced Expiration

Involves active muscle contraction such as abdominal and internal intercostal muscles.

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Muscles of Expiration

Include internal intercostal muscles and abdominal wall muscles during forced expiration.

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Respiratory Rate

The normal rate of breathing, typically 12-16 cycles per minute.

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Lung Compliance

The stretchiness of the lungs, defined as volume change per unit pressure change.

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Inspiratory compliance curve

A curve indicating lung capacity adaptation during inhalation.

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Expiratory compliance curve

A curve showing lung capacity adaptation during exhalation.

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Surfactant

A substance reducing surface tension in the alveoli, aiding lung compliance.

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Elastic forces in lungs

Forces from elastic tissues and alveolar fluid affecting lung compliance.

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Factors reducing compliance

Conditions like pulmonary edema and lung engorgement that impair lung expansion.

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COPD and compliance

Increased compliance due to degeneration of alveolar walls in COPD conditions.

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Surface tension and alveoli

The film of fluid that lines alveoli, affecting expansion and compression.

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Mechanics of Breathing

The process involving the movement of air into and out of the lungs, influenced by lung and thoracic structure.

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Compliance of the lungs

The measurement of the lung's ability to stretch and expand; it indicates the lung's elasticity.

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Role of Surfactant

A substance that reduces surface tension in the alveoli, increasing lung compliance and preventing collapse.

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Airway Resistance

The resistance encountered by air as it flows through the airways, influenced by airway diameter and lung volume.

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Diaphragm

The main muscle used in breathing, contracting during inspiration to increase thoracic volume.

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Accessory muscles of inspiration

Additional muscles (like sternocleidomastoid) used during forced inspiration to raise the thoracic cage further.

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Pleural space

The space filled with pleural fluid between the lungs and thoracic wall, helping to keep the lungs inflated.

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Elastic recoil

The tendency of the lungs to return to their resting state after inhalation, balanced by chest wall expansion.

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Surface Tension

The force that causes the molecules at the surface of a liquid to be attracted more to each other than to the air above.

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Law of Laplace

A principle stating that the pressure within a bubble is determined by its radius and surface tension, expressed as P = 2T/r.

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Alveolus Expansion

As an alveolus expands, its radius increases while surfactant molecules spread, affecting surface tension.

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Pressure in Alveolus

The internal pressure (P) in an alveolus, influenced by surface tension (T) and radius (r).

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Lung Stability

Surfactant prevents small alveoli from collapsing into larger ones, helping to stabilize the lung structure.

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Respiratory Distress Syndrome

A condition in infants caused by the absence of surfactant, especially in those younger than 25 weeks gestation.

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Poiseuille's Law

Equation that describes airflow resistance in a tube: Resistance = (Pressure x Length) / (Radius^4).

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Alveoli

Tiny air sacs in the lungs that are responsible for gas exchange.

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Acute Respiratory Distress Syndrome (ARDS)

A serious lung condition caused by fluid accumulation, leading to decreased oxygenation.

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Study Notes

Respiratory Module - Session 3: Mechanics of Breathing

  • Learning Outcomes:
    • Describe the mechanical system of the lungs and thorax.
    • Define and explain how lung compliance is measured.
    • Describe factors influencing lung compliance, including the role of surfactant.
    • Explain factors influencing airway resistance and how it changes during respiration.

Objective 1: Mechanical System of Lungs & Thorax

  • Inspiration is an active process.
  • The pleural space, between the lungs and thoracic wall, contains fluid forming a seal.
  • Changes in the volume of the thorax cage directly affect the volume of the lungs.

Objective 2: Defining Lung Compliance

  • Lung compliance is the stretchiness or distensibility of the lungs.
  • Compliance is defined as the volume change per unit of pressure change.
  • It's measured by applying a pressure change and measuring the resulting volume change.

Objective 3: Factors Affecting Lung Compliance

  • Lung elasticity comes from lung tissues and surface tension in alveoli.
  • Surfactant reduces surface tension, crucial for lung compliance.
  • Reduced compliance happens when: pulmonary venous pressure increases, alveolar edema occurs, or the lung is unventilated.
  • Diseases causing lung fibrosis also reduce compliance.
  • In COPD (e.g., emphysema), alveolar walls degenerate increasing compliance.
  • Asthma usually has normal lung compliance

Objective 4: Airway Resistance

  • Airway resistance is determined by pressure, viscosity, length and radius of the tube (airway).

  • Airways are connected in parallel. This lowers resistance compared to single, long flow.

  • In normal breathing, airway resistance is minimal in the lower respiratory tract compared to the upper respiratory tract.

  • Airway resistance increase during forced exhalation.

  • Summary of mechanics:

    • Work is done during breathing against elastic recoil forces of lungs and thorax, primarily focused on lung tissue and alveolar surface tension.
    • Airway resistance is usually negligible to total breathing work in healthy individuals but it can be affected by disease.

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