Respiratory Mechanics

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Questions and Answers

What is the volume of air remaining in the lungs after expiration of a normal breath?

  • 4.5 L
  • 2.5 L (correct)
  • 3.5 L
  • 1.5 L

What is the most common cause of death related to idiopathic pulmonary fibrosis?

  • Pulmonary hypertension
  • Lung cancer
  • Pulmonary embolism
  • Respiratory failure (correct)

How many people in the US are currently affected by idiopathic pulmonary fibrosis?

  • 132,000 (correct)
  • 100,000
  • 50,000
  • 200,000

What is the definition of airway resistance?

<p>The change of pressure from the alveoli to the mouth divided by the change in flow rate (C)</p> Signup and view all the answers

What happens to airway resistance as lung volume is reduced?

<p>It significantly increases (A)</p> Signup and view all the answers

What is the importance of surfactant at birth?

<p>It helps the infant's lungs expand after birth (C)</p> Signup and view all the answers

What is the result of surfactant deficiency in infants?

<p>Respiratory Distress Syndrome (RDS) (C)</p> Signup and view all the answers

What is the cellular mechanism involved in the development of IPF?

<p>Epithelial cell apoptosis and endoplasmic reticulum stress (C)</p> Signup and view all the answers

What is the significance of the bronchi and bronchioles in airway resistance?

<p>They significantly contribute to airway resistance (D)</p> Signup and view all the answers

What is the effect of contraction of the smooth muscle that lines the bronchial airways?

<p>It increases airway resistance (D)</p> Signup and view all the answers

What is the pressure in the intrapleural space normally?

<p>-2.5 mm Hg (A)</p> Signup and view all the answers

What happens to the lungs if the chest wall is opened?

<p>They collapse (D)</p> Signup and view all the answers

What is the process of inspiration?

<p>An active process (A)</p> Signup and view all the answers

What happens to the pressure in the airways at the end of inspiration?

<p>It becomes slightly positive (B)</p> Signup and view all the answers

What is the volume of air that moves into the lungs with each inspiration during quiet breathing?

<p>500-750 mL (C)</p> Signup and view all the answers

What is the volume of air that can be exhaled from the lungs after passive expiration?

<p>Expiratory Reserve Volume (ERV) (D)</p> Signup and view all the answers

What is the total amount of air in the lungs after maximum inhalation?

<p>Total Lung Capacity (TLC) (A)</p> Signup and view all the answers

What is the maximum amount of air that can be expired from the fully inflated lungs?

<p>Vital Capacity (VC) (B)</p> Signup and view all the answers

What is the process of expiration during quiet breathing?

<p>A passive process (D)</p> Signup and view all the answers

What is the maximum amount of air that can be inspired from the end-expiratory level?

<p>Inspiratory Capacity (IC) (D)</p> Signup and view all the answers

What is the primary reason for the retention of fluid in the lungs of infants with IRDS?

<p>Immaturity of epithelial Na+ channels (D)</p> Signup and view all the answers

What is the approximate volume of anatomic dead space in a 70 kg person?

<p>300 mL (D)</p> Signup and view all the answers

What is the cause of pulmonary alveolar proteinosis?

<p>Overproduction of surfactant proteins (D)</p> Signup and view all the answers

What is the primary factor that determines the diffusing capacity of the lungs for a given gas?

<p>Surface area of the alveolocapillary membrane (A)</p> Signup and view all the answers

What is the significance of the first 150 mL expired during expiration?

<p>It is the gas that occupies the dead space (C)</p> Signup and view all the answers

What is the effect of rapid shallow breathing on alveolar ventilation?

<p>It decreases alveolar ventilation (B)</p> Signup and view all the answers

What is the reason for the difference between RMV and alveolar ventilation?

<p>The difference in the volume of anatomic dead space (D)</p> Signup and view all the answers

What is the purpose of measuring the diffusing capacity for CO (DLCO)?

<p>To measure the diffusing capacity of the lungs as an index (B)</p> Signup and view all the answers

What is the effect of immaturity of epithelial Na+ channels on the lungs of infants with IRDS?

<p>It decreases the absorption of Na+ (C)</p> Signup and view all the answers

What is the primary site of gas exchange in the respiratory system?

<p>The alveoli (D)</p> Signup and view all the answers

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