Podcast
Questions and Answers
What is the primary function of glycolysis in glucose metabolism?
What is the primary function of glycolysis in glucose metabolism?
- To cleave glucose into pyruvate and produce ATP (correct)
- To convert lactate back to glucose
- To synthesize fatty acids from glucose
- To store excess glucose as glycogen
What happens to pyruvate in aerobic metabolism?
What happens to pyruvate in aerobic metabolism?
- It is converted to lactate
- It is stored as glycogen
- It is oxidized to acetyl coenzyme A (correct)
- It is directly converted to ATP
Which cofactor is reduced during the glycolytic pathway?
Which cofactor is reduced during the glycolytic pathway?
- NAD (correct)
- ATP
- CoA
- FAD
What occurs during anaerobic glycolysis?
What occurs during anaerobic glycolysis?
What role does the electron transport chain play in cellular respiration?
What role does the electron transport chain play in cellular respiration?
What happens to NADH during the conversion of pyruvate to lactate?
What happens to NADH during the conversion of pyruvate to lactate?
What effect does lactate accumulation have on intracellular pH?
What effect does lactate accumulation have on intracellular pH?
What is the final product of the citric acid cycle?
What is the final product of the citric acid cycle?
Why can't muscle tissue export glucose released from its glycogen stores?
Why can't muscle tissue export glucose released from its glycogen stores?
What is the primary fuel used by muscles during contraction?
What is the primary fuel used by muscles during contraction?
What is the main product formed during beta oxidation of fatty acids?
What is the main product formed during beta oxidation of fatty acids?
Which structure receives oxygenated blood from the pulmonary veins?
Which structure receives oxygenated blood from the pulmonary veins?
What must happen to fatty acids before they can enter the mitochondria for oxidation?
What must happen to fatty acids before they can enter the mitochondria for oxidation?
What is the primary function of the hepatic portal vein?
What is the primary function of the hepatic portal vein?
What is the energy yield from a gram of fatty acids compared to carbohydrates?
What is the energy yield from a gram of fatty acids compared to carbohydrates?
What is the process called when fat stored in fat cells is broken down into free fatty acids?
What is the process called when fat stored in fat cells is broken down into free fatty acids?
How does blood leave the kidneys?
How does blood leave the kidneys?
What happens to glycerol released during lipolysis?
What happens to glycerol released during lipolysis?
What is the role of the pulmocutaneous arch in the circulatory system?
What is the role of the pulmocutaneous arch in the circulatory system?
Which of the following animals have a four-chambered heart?
Which of the following animals have a four-chambered heart?
Which compound is primarily formed from hepatic glycerol 3-phosphate?
Which compound is primarily formed from hepatic glycerol 3-phosphate?
What distinguishes the circulatory system of reptiles from that of amphibians?
What distinguishes the circulatory system of reptiles from that of amphibians?
Which component does NOT exist in the circulatory systems of birds and mammals?
Which component does NOT exist in the circulatory systems of birds and mammals?
What is the result of blood mixing in the ventricle?
What is the result of blood mixing in the ventricle?
What is the primary function of the atrioventricular (AV) node in the heart's conducting system?
What is the primary function of the atrioventricular (AV) node in the heart's conducting system?
How is the speed of conduction in the AV node described?
How is the speed of conduction in the AV node described?
What is the role of the Purkinje fibers in the heart?
What is the role of the Purkinje fibers in the heart?
What does the P wave in an electrocardiogram (ECG) represent?
What does the P wave in an electrocardiogram (ECG) represent?
Which statement accurately describes the relationship between blood pressure readings?
Which statement accurately describes the relationship between blood pressure readings?
Which nervous system influences the heart rate by causing bradycardia?
Which nervous system influences the heart rate by causing bradycardia?
What prevents backflow in lymph vessels?
What prevents backflow in lymph vessels?
What does tachycardia refer to in the context of heart function?
What does tachycardia refer to in the context of heart function?
What role does the circulatory system play in temperature regulation?
What role does the circulatory system play in temperature regulation?
Which of the following best describes an open circulatory system?
Which of the following best describes an open circulatory system?
Which component is part of the venous system in amphibians?
Which component is part of the venous system in amphibians?
What is the primary function of hormones transported by the circulatory system?
What is the primary function of hormones transported by the circulatory system?
Which circulatory system type is characterized by blood being pumped from the heart and leaving the blood vessels?
Which circulatory system type is characterized by blood being pumped from the heart and leaving the blood vessels?
Which chamber structure is found in the amphibian heart?
Which chamber structure is found in the amphibian heart?
The closed circulatory system is primarily characterized by which of the following?
The closed circulatory system is primarily characterized by which of the following?
How does the circulatory system aid in immunity?
How does the circulatory system aid in immunity?
What is the primary role of the scalenes and sternocleidomastoid muscles during active inspiration?
What is the primary role of the scalenes and sternocleidomastoid muscles during active inspiration?
During strenuous exercise, how is ventilation affected?
During strenuous exercise, how is ventilation affected?
What percentage of oxygen is transported by haemoglobin in the blood?
What percentage of oxygen is transported by haemoglobin in the blood?
Which group is responsible for normal quiet inspiration?
Which group is responsible for normal quiet inspiration?
What mechanism occurs during active expiration?
What mechanism occurs during active expiration?
How is carbon dioxide primarily transported in the blood?
How is carbon dioxide primarily transported in the blood?
What happens to the thoracic cavity during active expiration?
What happens to the thoracic cavity during active expiration?
What is the approximate action potential generation rate for DRG under normal conditions?
What is the approximate action potential generation rate for DRG under normal conditions?
Flashcards
Glycolysis
Glycolysis
The first pathway in glucose oxidation, breaking down a glucose molecule into two pyruvate molecules, producing a net gain of two ATP molecules per glucose molecule.
Pyruvate
Pyruvate
A three-carbon compound formed from glucose during glycolysis, further processed in either aerobic or anaerobic metabolism.
Aerobic Metabolism
Aerobic Metabolism
Glucose oxidation process that requires oxygen and produces a large amount of ATP through the citric acid cycle and electron transport chain.
Citric Acid Cycle
Citric Acid Cycle
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Anaerobic Glycolysis
Anaerobic Glycolysis
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Lactate
Lactate
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ATP
ATP
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Acetyl CoA
Acetyl CoA
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Muscle glycogen use
Muscle glycogen use
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Lipolysis
Lipolysis
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Beta-oxidation
Beta-oxidation
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Fatty acid activation
Fatty acid activation
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Fatty acid oxidation
Fatty acid oxidation
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Energy yield of fats
Energy yield of fats
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Amino acid uses
Amino acid uses
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Ketones in ketosis
Ketones in ketosis
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Open Circulatory System
Open Circulatory System
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Closed Circulatory System
Closed Circulatory System
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Transport Hormones
Transport Hormones
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Immunity
Immunity
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Body Temperature Regulation
Body Temperature Regulation
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Amphibian Heart Chambers
Amphibian Heart Chambers
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Sinus Venosus
Sinus Venosus
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Pulmonary Vein
Pulmonary Vein
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Atrial Contraction
Atrial Contraction
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AV Node
AV Node
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Bundle of His
Bundle of His
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Purkinje Fibers
Purkinje Fibers
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Blood Pressure
Blood Pressure
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Systolic Pressure
Systolic Pressure
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Diastolic Pressure
Diastolic Pressure
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ECG (Electrocardiogram)
ECG (Electrocardiogram)
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Reptilian Circulatory System
Reptilian Circulatory System
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Crocodile Circulatory System
Crocodile Circulatory System
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Pulmonary Circulation
Pulmonary Circulation
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Systemic Circulation
Systemic Circulation
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Venous portal system
Venous portal system
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Hepatic Portal System
Hepatic Portal System
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Mixed Blood
Mixed Blood
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Four-chambered heart
Four-chambered heart
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Forceful Inspiration
Forceful Inspiration
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Forceful Expiration
Forceful Expiration
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Oxygen Transport (Blood)
Oxygen Transport (Blood)
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CO2 Transport (Blood)
CO2 Transport (Blood)
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Dorsal Respiratory Group (DRG)
Dorsal Respiratory Group (DRG)
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Respiratory Rate (Exercise)
Respiratory Rate (Exercise)
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Inspiration Time (Exercise)
Inspiration Time (Exercise)
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Ventilation
Ventilation
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Study Notes
Respiration and Respiratory System
- Respiration provides cells with oxygen for energy production and removes carbon dioxide
- Different respiratory methods exist in the animal kingdom
Types of Respiration in Animals
- Direct exchange of gases between cells and the environment (protozoa, porifera, coelenterata, platyhelminthes)
- Direct exchange of gases between blood and the environment (annelida)
- Respiration through spiracles leading to trachea (insects)
- Respiration through gills (fish)
- Respiration through lungs (land vertebrates)
Structure of the Respiratory System
- Nostrils: Warm, filter, and moisten air
- Nasal passages: Open areas in the nose
- Pharynx: Throat, where air passes
- Larynx: Voice box, constructed mainly from cartilage, with vocal chords for sound production
- Trachea: Windpipe, kept open by cartilage rings, with cilia to remove foreign particles
- Bronchi: Branch from trachea, enter the lungs, and spread into finer tubes
- Bronchioles: Very thin tubes that subdivide further
- Lungs: Located in the chest cavity, filled with alveoli for gas exchange
Mechanism of External Respiration
- Inspiration: Ribs are pushed outward, diaphragm contracts, thoracic cavity increases in size, causing air to enter lungs
- Expiration: Ribs and diaphragm relax, decreasing thoracic cavity size, forcing air out
Mechanisms of Forceful Respiration During Exercise
- In active inspiration, additional muscles contract to increase rib movement and stretch the lungs, allowing more air into the lungs
- In active expiration, additional muscles contract to further decrease thoracic cavity size and expel more air
Transport of Oxygen and Carbon Dioxide in the Blood
- 98% of oxygen is transported bound to hemoglobin (oxyhemoglobin)
- 2% of oxygen is dissolved in blood plasma
- Carbon dioxide is transported in three forms:
- Dissolved in blood plasma
- Bound to hemoglobin (carbaminohemoglobin)
- As bicarbonate ions
Nervous Control of External Respiration
- Dorsal respiratory group (DRG): Responsible for normal quiet breathing, spontaneously generating signals for about 15 times per minute
- Ventral respiratory group (VRG): Responsible for forceful breathing
- Pneumotaxic center: Influences the rate of breathing
- Apneustic center: Prolongs inspiration
Respiratory Volumes and Capacities
- Tidal volume (TV): Amount of air inhaled or exhaled in a normal breath (about 500mL)
- Inspiratory Reserve Volume (IRV): Additional air that can be inhaled forcefully (about 3000mL)
- Expiratory Reserve Volume (ERV): Additional air that can be exhaled forcefully (about 1200mL)
- Residual Volume (RV): Air remaining in the lungs after maximal exhalation (about 1200mL).
- Inspiratory Capacity (IC): The sum of tidal volume and inspiratory reserve volume (about 3500mL)
- Functional Residual Capacity (FRC): The sum of expiratory reserve volume and residual volume (about 2400mL)
- Vital capacity (VC): The maximum volume of air that can be moved in and out of the lungs (about 4800mL)
- Total lung capacity (TLC): The sum of all lung volumes (about 6000mL)
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