Resistance to Antimicrobial Drugs Mechanisms

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Questions and Answers

What is one of the mechanisms by which microorganisms resist antimicrobial drugs?

  • Changing their color to match the drug
  • Developing an altered sensory perception of the drug
  • Increasing their permeability to the drug
  • Producing enzymes that destroy the active drug (correct)

Which resistance mechanism is specifically mentioned as causing penicillin resistance in Streptococcus pneumoniae and enterococci?

  • Altering structural target for the drug (correct)
  • Developing altered metabolic pathways
  • Changing permeability to the drug
  • Developing efflux pumps

What does the development of an altered enzyme by microorganisms in resistance to drugs help them achieve?

  • Increased sensitivity to the drug
  • Maintaining unaffected metabolic functions (correct)
  • Improved permeability to the drug
  • Creating stronger bonds with the drug

Which type of microorganisms commonly develop efflux pumps as a resistance mechanism against antibiotics?

<p>Gram-positive and some gram-negative organisms (B)</p> Signup and view all the answers

What effect does altering the permeability to the drug have on microorganisms' resistance?

<p>It impairs active transport of the drug into the cell (A)</p> Signup and view all the answers

In what way do microorganisms develop resistance when they change their metabolic pathways?

<p>By bypassing the reaction inhibited by the drug (D)</p> Signup and view all the answers

What is one way in which microorganisms exhibit resistance to antimicrobial drugs by altering their structural target for the drug?

<p>Developing an altered metabolic pathway (B)</p> Signup and view all the answers

How does the altered metabolic pathway contribute to microorganisms' resistance to antimicrobial drugs?

<p>By bypassing the reaction inhibited by the drug (C)</p> Signup and view all the answers

Which enzyme is specifically mentioned in the text as contributing to resistance by being less affected by antimicrobial drugs?

<p>β-lactamase (B)</p> Signup and view all the answers

In what way do microorganisms demonstrate resistance by developing efflux pumps?

<p>By transporting the antibiotics out of the cell (A)</p> Signup and view all the answers

How does altering the permeability to the drug affect microorganisms' resistance to antimicrobial drugs?

<p>Impairing active transport into the cell (C)</p> Signup and view all the answers

Which type of microorganism develops resistance by producing an altered pathogen binding protein (PBP)?

<p>Gram-positive bacteria (C)</p> Signup and view all the answers

What is a common mechanism by which microorganisms resist antimicrobial drugs by developing enzymes that destroy the active drug?

<p>Producing β-lactamase (C)</p> Signup and view all the answers

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