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Resistance to Antimicrobial Drugs Mechanisms

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Resistance to Antimicrobial Drugs Mechanisms

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Questions and Answers

What is one of the mechanisms by which microorganisms resist antimicrobial drugs?

Changing their color to match the drug

Developing an altered sensory perception of the drug

Increasing their permeability to the drug

Producing enzymes that destroy the active drug (correct)

Which resistance mechanism is specifically mentioned as causing penicillin resistance in Streptococcus pneumoniae and enterococci?

Altering structural target for the drug (correct)

Developing altered metabolic pathways

Changing permeability to the drug

Developing efflux pumps

What does the development of an altered enzyme by microorganisms in resistance to drugs help them achieve?

Increased sensitivity to the drug

Maintaining unaffected metabolic functions (correct)

Improved permeability to the drug

Creating stronger bonds with the drug

Which type of microorganisms commonly develop efflux pumps as a resistance mechanism against antibiotics?

Gram-positive and some gram-negative organisms Signup and view all the answers

What effect does altering the permeability to the drug have on microorganisms' resistance?

It impairs active transport of the drug into the cell Signup and view all the answers

In what way do microorganisms develop resistance when they change their metabolic pathways?

By bypassing the reaction inhibited by the drug Signup and view all the answers

What is one way in which microorganisms exhibit resistance to antimicrobial drugs by altering their structural target for the drug?

Developing an altered metabolic pathway Signup and view all the answers

How does the altered metabolic pathway contribute to microorganisms' resistance to antimicrobial drugs?

By bypassing the reaction inhibited by the drug Signup and view all the answers

Which enzyme is specifically mentioned in the text as contributing to resistance by being less affected by antimicrobial drugs?

β-lactamase Signup and view all the answers

In what way do microorganisms demonstrate resistance by developing efflux pumps?

By transporting the antibiotics out of the cell Signup and view all the answers

How does altering the permeability to the drug affect microorganisms' resistance to antimicrobial drugs?

Impairing active transport into the cell Signup and view all the answers

Which type of microorganism develops resistance by producing an altered pathogen binding protein (PBP)?

Gram-positive bacteria Signup and view all the answers

What is a common mechanism by which microorganisms resist antimicrobial drugs by developing enzymes that destroy the active drug?

Producing β-lactamase Signup and view all the answers