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Research Ethics and Methodology

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Questions and Answers

What is essential to obtain from research subjects who are able to provide it before they participate in a medical research?

Verbal consent
Parental consent
Witness signature
Written informed consent (correct)

What is the primary purpose of disclosing funding sources and potential conflicts of interest in research?

To ensure transparency and accountability (correct)
To justify study outcomes
To acknowledge research assistants
To secure additional funding

Why is it essential to protect the privacy and confidentiality of research subjects?

To maintain trust between researchers and participants (correct)
To obtain better study outcomes
To ensure informed consent
To reduce study costs

What should be tested against when introducing a new intervention in medical research?

The best proven treatment that presently exists (B) Signup and view all the answers

What special consideration exists for research subjects who are incapable of giving informed consent due to mental or physical incapacity?

Obtaining consent from a legally authorized representative (A) Signup and view all the answers

What is the primary purpose of using a placebo in medical research?

To provide a treatment with no active properties (D) Signup and view all the answers

What is the primary purpose of using placebos in clinical trials?

To understand the real effect of the new treatment and distinguish it from the placebo effect (A) Signup and view all the answers

What should happen to participants in a trial if the intervention is identified as beneficial?

They are offered post-trial access to the intervention (C) Signup and view all the answers

Why must researchers register their studies in a publicly accessible database?

To comply with ethical obligations and ensure transparency (A) Signup and view all the answers

What is the researchers' ethical obligation upon completing a trial?

To share complete and accurate results, including negative or inconclusive findings (D) Signup and view all the answers

What can be a factor in the placebo effect?

A person's belief in the treatment (A) Signup and view all the answers

What is the primary consideration when conducting medical research?

The importance of the findings outweighing the risks and burdens to the research subjects (B) Signup and view all the answers

Who should supervise medical research?

A qualified physician or healthcare professional (D) Signup and view all the answers

What is a key principle of protecting vulnerable populations in medical research?

Special protections must be implemented to protect vulnerable individuals and groups (B) Signup and view all the answers

What should happen if the risks of a research study start to outweigh the potential benefits?

The study should be immediately stopped (A) Signup and view all the answers

What is the basis for medical research, according to the Declaration of Helsinki?

Sound scientific inquiry (B) Signup and view all the answers

What is a key consideration in minimizing harm to research subjects?

Monitored and mitigated risks (A) Signup and view all the answers

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