Repair and Regeneration in the Nervous System

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Which of the following is NOT a barrier that impedes central nervous system regeneration?

Reactivation of developmental processes for axon growth (correct)

Local overgrowth of glial cells

Signals produced by glial cells that inhibit neuron growth

Failure of repair over limited distances

After stroke or injury to distinct brain regions, patients often recover some of the deficits seen immediately after the trauma. This recovery is most often the result of:

Reorganization of intact circuits (correct)

Restoration of damaged central nerve cells

Genesis of new neurons

Regrowth or replacement of damaged neurons

Which type of neuronal repair is the most clinically successful in the nervous system?

Regrowth of axons

Genesis of new neurons

Restoration of damaged central nerve cells

Peripheral nerve regeneration (correct)

Which of the following is a key difference between peripheral nerve regeneration and regeneration in the central nervous system?

Peripheral nerve regeneration is more successful in restoring sensory and motor function, while regeneration in the central nervous system has a relatively poor prognosis. Signup and view all the answers

What is the role of Schwann cells in peripheral nerve regeneration?

Schwann cells secrete growth-promoting signaling molecules that facilitate axon regrowth. Signup and view all the answers

Why is there limited regeneration in the central nervous system following injury?

Microglial activity actively inhibits axon growth after brain injury. Signup and view all the answers

Which of the following is NOT one of the three types of neuronal repair mentioned in the text?

Functional reorganization without repair Signup and view all the answers

In humans, new nerve cells in the CNS are reliably generated in which two regions?

The olfactory bulb and the hippocampus Signup and view all the answers

Which of the following is a barrier to neuronal regrowth in the adult brain?

Enhanced immune responses Signup and view all the answers

When were cortical neurons generated over an individual's lifetime affected by fluctuations in environmental exposure to radioisotopes from nuclear weapons testing?

Mid 1950s to early 1960s Signup and view all the answers

Which of the following is NOT a region in the central nervous system where new nerve cells are reliably generated in humans?

Cerebellum Signup and view all the answers

What is the main reason for the limited capacity of the adult brain to replace neurons?

Immune responses Signup and view all the answers

Which of the following vertebrates have the capacity for neurogenesis in response to brain injury?

Songbirds Signup and view all the answers

What is the main role of GABAergic interneurons in the CNS?

Inhibitory signaling Signup and view all the answers

When were cortical neurons generated over an individual's lifetime affected by fluctuations in environmental exposure to radioisotopes from nuclear weapons testing?

1960s Signup and view all the answers

Which of the following is NOT a barrier to neuronal regrowth in the adult brain?

Enhanced immune responses Signup and view all the answers

Why is there limited regeneration in the central nervous system following injury?

Inhibition by glial cells Signup and view all the answers

Which of the following vertebrates have the capacity for neurogenesis in response to brain injury?

Birds Signup and view all the answers

In humans, new nerve cells in the CNS are reliably generated in which two regions?

Olfactory bulb and hippocampus Signup and view all the answers

What is the main role of GABAergic interneurons in the CNS?

Inhibition of neurons Signup and view all the answers

Repair and Regeneration in the Nervous System

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Questions and Answers

Which of the following is NOT a barrier that impedes central nervous system regeneration?

After stroke or injury to distinct brain regions, patients often recover some of the deficits seen immediately after the trauma. This recovery is most often the result of:

Which type of neuronal repair is the most clinically successful in the nervous system?

Which of the following is a key difference between peripheral nerve regeneration and regeneration in the central nervous system?

What is the role of Schwann cells in peripheral nerve regeneration?

Why is there limited regeneration in the central nervous system following injury?

Which of the following is NOT one of the three types of neuronal repair mentioned in the text?

In humans, new nerve cells in the CNS are reliably generated in which two regions?

Which of the following is a barrier to neuronal regrowth in the adult brain?

When were cortical neurons generated over an individual's lifetime affected by fluctuations in environmental exposure to radioisotopes from nuclear weapons testing?

Which of the following is NOT a region in the central nervous system where new nerve cells are reliably generated in humans?

What is the main reason for the limited capacity of the adult brain to replace neurons?

Which of the following vertebrates have the capacity for neurogenesis in response to brain injury?

What is the main role of GABAergic interneurons in the CNS?

When were cortical neurons generated over an individual's lifetime affected by fluctuations in environmental exposure to radioisotopes from nuclear weapons testing?

Which of the following is NOT a barrier to neuronal regrowth in the adult brain?

Why is there limited regeneration in the central nervous system following injury?

Which of the following vertebrates have the capacity for neurogenesis in response to brain injury?

In humans, new nerve cells in the CNS are reliably generated in which two regions?

What is the main role of GABAergic interneurons in the CNS?

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