Renal System Lec 2 Clinical Chemistry
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Questions and Answers

What is the main outcome of reduced GFR and normal tubular function on hydrogen ion secretion throughout the nephron?

  • Reduced hydrogen ion secretion leading to fall in plasma bicarbonate concentrations (correct)
  • Increased hydrogen ion secretion leading to acidosis
  • Increased hydrogen ion secretion leading to rise in plasma bicarbonate concentrations
  • No effect on hydrogen ion secretion

    • What is the net effect of reduced GFR and normal tubular function on plasma and urine?

  • Low bicarbonate concentration in plasma, reduced urine volume
  • Low urea and creatinine concentrations in plasma, increased urine volume
  • High urea and creatinine concentrations in plasma, reduced urine volume (correct)
  • High bicarbonate concentration in plasma, increased urine volume

    • What is the impact of reduced GFR and normal tubular function on potassium retention?

  • Increased potassium retention due to reduced potassium secretion in the distal tubule (correct)
  • Increased potassium retention due to increased potassium secretion in the distal tubule
  • No impact on potassium retention
  • Decreased potassium retention due to increased potassium secretion in the proximal tubule

    • What are the typical plasma characteristics associated with reduced GFR and normal tubular function?

    <p>High urea (uraemia) and creatinine concentrations, low bicarbonate concentration with low pH (acidosis), hyperkalaemia</p> Signup and view all the answers

    What is the impact of impaired solute reabsorption from proximal tubules on water reabsorption?

    <p>Reduces isosmotic water reabsorption</p> Signup and view all the answers

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