5 Questions
What is the main outcome of reduced GFR and normal tubular function on hydrogen ion secretion throughout the nephron?
Reduced hydrogen ion secretion leading to fall in plasma bicarbonate concentrations
What is the net effect of reduced GFR and normal tubular function on plasma and urine?
High urea and creatinine concentrations in plasma, reduced urine volume
What is the impact of reduced GFR and normal tubular function on potassium retention?
Increased potassium retention due to reduced potassium secretion in the distal tubule
What are the typical plasma characteristics associated with reduced GFR and normal tubular function?
High urea (uraemia) and creatinine concentrations, low bicarbonate concentration with low pH (acidosis), hyperkalaemia
What is the impact of impaired solute reabsorption from proximal tubules on water reabsorption?
Reduces isosmotic water reabsorption
This quiz covers the net effect of renal disease on plasma and urine, focusing on the proportion of glomeruli to tubules affected and the number of nephrons involved. It also explores the impact of reduced GFR and normal tubular function on filtered phosphate, urate, and sodium levels.
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