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Renal Function and Creatinine Clearance

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Questions and Answers

What are the three measurements required to calculate creatinine clearance?

Urine volume, plasma creatinine, and body surface area
Height, weight, and urine creatinine
Urine creatinine, plasma creatinine, and urine volume (correct)
Duration of collection, plasma creatinine, and urine volume

What is the standard body surface area to which creatinine clearance is adjusted?

2.13m2
1.73m2 (correct)
2.00m2
1.93m2

Why does serum creatinine remain constant with age?

Due to increased muscle mass
Due to increased kidney function
Due to increased liver function
Due to decreased muscle mass (correct)

What may affect the reliability of calculated creatinine clearance?

Patient's sloppy urine collection and dietary intake (D) Signup and view all the answers

Where does synthesis of new creatine mainly occur?

Liver (A) Signup and view all the answers

What is the most widely used plasma marker of GFR?

Plasma creatinine (D) Signup and view all the answers

Why is creatinine clearance a relatively easy test to perform?

It is relatively cheap and does not require an intravenous infusion (B) Signup and view all the answers

What is the formula for calculating creatinine clearance?

Urine creatinine / plasma creatinine x urine volume / duration of collection (C) Signup and view all the answers

Why may a patient's health problem affecting skeletal muscle affect creatinine clearance?

Because it affects muscle mass and creatinine production (A) Signup and view all the answers

What may a patient's temptation to eat a steak during the test affect?

Urine creatinine levels (D) Signup and view all the answers