Renal Function and Creatinine Clearance
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Questions and Answers

What are the three measurements required to calculate creatinine clearance?

  • Urine volume, plasma creatinine, and body surface area
  • Height, weight, and urine creatinine
  • Urine creatinine, plasma creatinine, and urine volume (correct)
  • Duration of collection, plasma creatinine, and urine volume

What is the standard body surface area to which creatinine clearance is adjusted?

  • 2.13m2
  • 1.73m2 (correct)
  • 2.00m2
  • 1.93m2

Why does serum creatinine remain constant with age?

  • Due to increased muscle mass
  • Due to increased kidney function
  • Due to increased liver function
  • Due to decreased muscle mass (correct)

What may affect the reliability of calculated creatinine clearance?

<p>Patient's sloppy urine collection and dietary intake (D)</p> Signup and view all the answers

Where does synthesis of new creatine mainly occur?

<p>Liver (A)</p> Signup and view all the answers

What is the most widely used plasma marker of GFR?

<p>Plasma creatinine (D)</p> Signup and view all the answers

Why is creatinine clearance a relatively easy test to perform?

<p>It is relatively cheap and does not require an intravenous infusion (B)</p> Signup and view all the answers

What is the formula for calculating creatinine clearance?

<p>Urine creatinine / plasma creatinine x urine volume / duration of collection (C)</p> Signup and view all the answers

Why may a patient's health problem affecting skeletal muscle affect creatinine clearance?

<p>Because it affects muscle mass and creatinine production (A)</p> Signup and view all the answers

What may a patient's temptation to eat a steak during the test affect?

<p>Urine creatinine levels (D)</p> Signup and view all the answers

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