Relationship Between Smoking, UC, Crohn's, and Other Factors
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Questions and Answers

What is the most likely cause of the patient's low hemoglobin level?

  • Chronic kidney disease
  • Excessive blood cell destruction
  • Insufficient iron intake (correct)
  • Genetic mutation in the hemoglobin molecule

Which of the following genetic factors is most strongly associated with an increased risk of developing Crohn's disease?

  • Mutations in the BRCA1 gene
  • Deletions in the CFTR gene
  • Variations in the NOD2 gene (correct)
  • Polymorphisms in the HLA-DRB1 gene

Which of the following nutritional deficiencies is most commonly observed in patients with Crohn's disease?

  • Vitamin D deficiency (correct)
  • Thiamine deficiency
  • Protein-energy malnutrition
  • Zinc deficiency

Which of the following factors is most strongly associated with the increasing incidence of Crohn's disease worldwide?

<p>Urbanization and westernized lifestyle (A)</p> Signup and view all the answers

Which of the following factors is most predictive of a favorable response to infliximab treatment in patients with Crohn's disease?

<p>Shorter disease duration (C)</p> Signup and view all the answers

Which of the following is the most common complication associated with long-term use of corticosteroids in the management of Crohn's disease?

<p>Osteoporosis (B)</p> Signup and view all the answers

What does a high white blood cell count, particularly high neutrophil count, indicate?

<p>High inflammation or infection levels (A)</p> Signup and view all the answers

How does an appendectomy relate to the development of ulcerative colitis (UC)?

<p>Decreases the risk of UC (D)</p> Signup and view all the answers

What is a common cause of megaloblastic anemia as mentioned in the text?

<p>Deficiency in vitamin B12 absorption (A)</p> Signup and view all the answers

Which dietary factor is associated with the onset of Crohn's disease according to the text?

<p>Regular consumption of refined carbohydrates (C)</p> Signup and view all the answers

What does a high platelet count indicate in the context of Crohn's disease?

<p>Presence of inflammation (A)</p> Signup and view all the answers

How does smoking impact the response to Infliximab in patients with Crohn's disease?

<p>Worsens the response (B)</p> Signup and view all the answers

Which of the following is the most likely cause of Kelly's mouth ulcers and cracked lips?

<p>Iron deficiency anemia (D)</p> Signup and view all the answers

What is the most significant genetic risk factor for developing Crohn's disease, based on the information provided?

<p>Kelly's mother having the condition (B)</p> Signup and view all the answers

Which of the following nutritional factors is most likely contributing to Kelly's Crohn's disease symptoms?

<p>Her consumption of ready meals (D)</p> Signup and view all the answers

What is the approximate incidence rate of Crohn's disease in the general population, based on the information provided?

<p>1 in 100 (C)</p> Signup and view all the answers

If Kelly is diagnosed with Crohn's disease, which of the following treatments would be the most appropriate initial therapy?

<p>Corticosteroids (C)</p> Signup and view all the answers

Which of the following factors is most likely to predict a good response to Infliximab treatment in Kelly, if she is diagnosed with Crohn's disease?

<p>Her lack of prior treatment (A)</p> Signup and view all the answers

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