Regulation of Traditional Medicines
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Questions and Answers

What are the main concerns about the regulation of traditional medicines in some countries?

Not properly funded and questionable identity, quality, purity, toxicological profile, and therapeutic efficacy.

What are the sources of uses for traditional medicines?

Folklore, experiences, skills, knowledge passed down for generations.

Define 'lead compounds' in the context of traditional medicines.

Pure compound of known structure having an appropriate level of activity in the primary screen.

What are the applications of pure phytochemicals in traditional medicines?

<p>Marker compounds for standardization and pharmacological tools.</p> Signup and view all the answers

Provide examples of traditional medicines derived from bioactive compounds.

<p>Digoxin, paclitaxel from Taxus spp.</p> Signup and view all the answers

What are the concerns related to the therapeutic efficacy of traditional medicines?

<p>Questionable.</p> Signup and view all the answers

What are the medically active components in medicinal plants?

<p>Phytochemicals, bioactive chemicals, active principles</p> Signup and view all the answers

How are medicinal plants traditionally applied?

<p>Poultices, Concoctions, Infusions, Tinctures, Porridges, Soups</p> Signup and view all the answers

What is the reason for the increasing use of traditionally used medicines?

<p>Increasing number of side effects and their seriousness related to modern synthetic drugs</p> Signup and view all the answers

What percentage of the world's population in developing countries use plant-based traditional medicines and herbal drugs for primary healthcare?

<p>About two thirds</p> Signup and view all the answers

What was the peak period for the investigation of natural products as a source of novel drugs?

<p>1970 – 1980</p> Signup and view all the answers

What factors contributed to the decline in natural products' investigation as a source of novel drugs?

<p>High Throughput Screening (HTS), Combinatorial chemistry, Molecular biology, Cellular biology, Genomics, Decline in interest in infectious disease therapy by major pharmaceuticals, Uncertainty on the exact process of biomaterials collection after 1992 Rio Convention on Biological Diversity</p> Signup and view all the answers

What are the various parts of medicinal plants that can be used for disease treatment and prevention?

<p>Whole plant, leaves, fruits, flowers, seeds, stems, stem barks, roots</p> Signup and view all the answers

What types of disease conditions can traditionally used medicinal plants treat?

<p>Asthma, constipation, infections, cancers, inflammations</p> Signup and view all the answers

What types of products can be derived from medicinal plants for disease treatment?

<p>Raw materials for semi-synthesis and synthesis of drugs</p> Signup and view all the answers

What percentage of new chemical entities (NCEs) introduced between 1981 – 2002 were related to natural products?

<p>Around 49%</p> Signup and view all the answers

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