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Regulation of CTLs

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@AmazedUvite

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Questions and Answers

Name two proteins that CTLs express upon successful activation.

Granzyme B and perforin.

What is the principal cytokine required for full proliferation and differentiation of effector CTLs?

IL-2.

Why are the stringent requirements for activation of CTLs important?

To prevent unwanted destruction.

What is the safeguard against inappropriate self-reactivity by CTLs?

<p>Both TH and TC cells recognizing antigen before the TC cell is optimally activated.</p> Signup and view all the answers

When is the IL-2 receptor expressed in CTLs?

<p>After a CTL-P cell has been activated by TCR engagement.</p> Signup and view all the answers

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