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Regulation of CTLs

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Questions and Answers

Name two proteins that CTLs express upon successful activation.

Granzyme B and perforin.

What is the principal cytokine required for full proliferation and differentiation of effector CTLs?

IL-2.

Why are the stringent requirements for activation of CTLs important?

To prevent unwanted destruction.

What is the safeguard against inappropriate self-reactivity by CTLs?

<p>Both TH and TC cells recognizing antigen before the TC cell is optimally activated.</p> Signup and view all the answers

When is the IL-2 receptor expressed in CTLs?

<p>After a CTL-P cell has been activated by TCR engagement.</p> Signup and view all the answers

Regulation of CTLs

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Podcast

Questions and Answers

Name two proteins that CTLs express upon successful activation.

What is the principal cytokine required for full proliferation and differentiation of effector CTLs?

Why are the stringent requirements for activation of CTLs important?

What is the safeguard against inappropriate self-reactivity by CTLs?

When is the IL-2 receptor expressed in CTLs?

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