Regulation of α and β Cells by Blood Glucose Levels

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Questions and Answers

What stimulates β cells to release insulin?

  • Somatostatin from δ cells
  • Increased glucose levels (correct)
  • Decreased glucose levels
  • Loss of insulin effect

What is the role of α cells when blood glucose levels decrease?

  • Inhibit glucagon release
  • Release insulin
  • Release glucagon (correct)
  • Inhibit insulin release

In Type 1 diabetes (IDDM), what causes the condition?

  • Failure of somatostatin release
  • Loss of the β cells from autoimmune destruction (correct)
  • Loss of the α cells
  • Loss of the insulin effect

What is a characteristic feature of Type 2 diabetes (NIDDM)?

<p>Failure to produce adequate insulin levels (D)</p> Signup and view all the answers

What happens in Type 2 diabetes commonly associated with obesity?

<p>Failure of peripheral target cells to respond to insulin (B)</p> Signup and view all the answers

How do α and β cells contribute to the control of blood glucose concentration?

<p>By opposing actions (A)</p> Signup and view all the answers

What is the main component of pars distalis in the adenohypophysis?

<p>Chromophils and chromophobes (D)</p> Signup and view all the answers

Which type of cells are known as basophils and acidophils based on their staining affinities?

<p>Chromophils (C)</p> Signup and view all the answers

How are subtypes of basophilic and acidophilic cells usually identified?

<p>By their granular morphology (B)</p> Signup and view all the answers

What is the characteristic of chromophobes in the pars distalis?

<p>They have clear cytoplasm without granules (C)</p> Signup and view all the answers

Which part of the adenohypophysis accounts for 75% of its composition?

<p>Pars Distalis (B)</p> Signup and view all the answers

What are the two broad groups of cells suggested by common stains in the pars distalis?

<p>&quot;Chromophils and chromophobes&quot; (A)</p> Signup and view all the answers

What stimulates melatonin release in periods of darkness?

<p>Sympathetic fibers (B)</p> Signup and view all the answers

Which pancreatic cell type produces glucagon?

<p>α (B)</p> Signup and view all the answers

What is the role of the pineal gland as described in the text?

<p>Converting sensory input regarding light and darkness into variations in hormonal functions (A)</p> Signup and view all the answers

What is the main function of insulin in the body?

<p>Decreases blood glucose content (B)</p> Signup and view all the answers

What type of cells are found in the pineal gland that represent about 5% of the cells?

<p>Interstitial glial cells (C)</p> Signup and view all the answers

Which hormone inhibits the release of other islet cell hormones?

<p>Somatostatin (C)</p> Signup and view all the answers

What are the concretions of calcium and magnesium salts called in the pineal gland?

<p>Corpora arenacea (A)</p> Signup and view all the answers

Where are the glial cells found within the pineal gland?

<p>In perivascular areas and between groups of pinealocytes (D)</p> Signup and view all the answers

What is the hormone produced by PP cells in the pancreas?

<p>Pancreatic polypeptide (D)</p> Signup and view all the answers

What determines the diurnal rhythms of hormone release and physiologic activities throughout the body?

<p>Levels of circulating melatonin (C)</p> Signup and view all the answers

Which pancreatic cell type secretes a hormone that stimulates activity of gastric chief cells?

<p>PP (C)</p> Signup and view all the answers

What is the hormone structure of glucagon?

<p>Polypeptide; 3500 Da (C)</p> Signup and view all the answers

What is the role of thyroid peroxidase in the iodination of tyrosyl residues in thyroglobulin?

<p>Catalyzing the oxidation of iodide to iodine (D)</p> Signup and view all the answers

How are T3 and T4 formed within the colloidal thyroglobulin?

<p>By coupling reactions between two iodinated tyrosines (D)</p> Signup and view all the answers

What is the main mechanism through which endocytosis of iodinated thyroglobulin occurs in thyrocytes?

<p>Both fluid-phase pinocytosis and receptormediated endocytosis (D)</p> Signup and view all the answers

Where do C cells typically reside in relation to the follicular epithelium?

<p>At the basement membrane of the follicle (C)</p> Signup and view all the answers

Which organelle is involved in degrading thyroglobulin with lysosomal proteases?

<p>Lysosomes (C)</p> Signup and view all the answers

What differentiates C cells from thyrocytes in terms of size and staining characteristics?

<p>C cells are larger and more pale stained than thyrocytes (B)</p> Signup and view all the answers

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