Red Blood Cell Viability and Preservation Quiz

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Questions and Answers

Which of the following is the correct composition of red blood cells?

  • 40% protein, 52% lipid, 8% carbohydrate
  • 8% lipid, 40% carbohydrate, 52% protein (correct)
  • 40% lipid, 8% carbohydrate, 52% protein
  • 8% protein, 52% lipid, 40% carbohydrate

Which of the following biochemical changes is NOT associated with loss of red blood cell viability upon storage?

  • Loss of red blood cell function
  • Decreased pH
  • Decreased glucose consumption
  • Increased ATP level (correct)

Which red blood cell preservative has a storage time of 35 days?

  • CPD
  • ACD
  • AS-1
  • CPDA-1 (correct)

Which of the following is NOT relatively permeable to the RBC membrane?

<p>Water (C)</p> Signup and view all the answers

What percentage of platelets is sequestered in the spleen as functional reserve after being released from the bone marrow?

<p>30% (D)</p> Signup and view all the answers

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Study Notes

Red Blood Cell Composition

  • Red blood cells are composed of a protein matrix, membranous lipids, and a high concentration of hemoglobin.

Biochemical Changes in Red Blood Cells

  • Upon storage, red blood cells undergo various biochemical changes, including depletion of ATP and 2,3-DPG, increase in lactate levels, and oxidative stress, but NOT an increase in glutathione levels.

Red Blood Cell Preservatives

  • CPDA-1 (citrate-phosphate-dextrose-adenine) is a red blood cell preservative with a storage time of 35 days.

Red Blood Cell Membrane Permeability

  • RBC membranes are relatively impermeable to Na+ ions.

Platelet Sequestration

  • Approximately 20-40% of platelets are sequestered in the spleen as a functional reserve after being released from the bone marrow.

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