Recurrent Bleeding in Severe Haemophilia
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Questions and Answers

What is a long-term sequel of Hemophilia A?

  • Permanent damage to knee and elbow joints (correct)
  • Painless hematuria
  • Muscle atrophy
  • Thrombin time prolonged

What is the main characteristic feature of Hemophilia A?

  • GI bleeding
  • Painless hematuria
  • Bleeding into joints (correct)
  • Bleeding into muscles

Which diagnostic test for Hemophilia A is usually normal in count?

  • Prothrombin Time
  • Thrombin Time
  • Activated Partial Thromboplastin Time
  • Platelets count (correct)

What is a major morbidity associated with recurrent bleeding in individuals with severe hemophilia?

<p>Deformities due to recurrent hemarthrosis (B)</p> Signup and view all the answers

Which complication can arise from muscle hematomas in individuals with hemophilia?

<p>Muscle atrophy (D)</p> Signup and view all the answers

What is a typical clotting factor deficiency observed in Hemophilia A?

<p>Factor VIII deficiency (B)</p> Signup and view all the answers

What is the major morbidity of recurrent bleeding in severe haemophilia?

<p>Musculoskeletal complications (C)</p> Signup and view all the answers

Which joint is NOT typically affected by bleeding in severe haemophilia?

<p>Wrists (C)</p> Signup and view all the answers

What happens if early treatment is not given to arrest bleeding in severe haemophilia?

<p>Development of hot, swollen, and painful joint or muscle hematomas (B)</p> Signup and view all the answers

Which factor is raised by intravenous infusion of factor VIII concentrate in the treatment of bleeding episodes in severe haemophilia A?

<p>Factor VIII (D)</p> Signup and view all the answers

What complication can arise from a large psoas bleed in patients with severe hemophilia?

<p>Femoral nerve compression (D)</p> Signup and view all the answers

What is a potential complication of calf hematomas in patients with severe hemophilia?

<p>Compartment syndrome (B)</p> Signup and view all the answers

What is a potential consequence of the depletion of haemostatic components in the context of disseminated intravascular coagulation?

<p>Haemorrhagic state (B)</p> Signup and view all the answers

Which cancer type is NOT associated with causing disseminated intravascular coagulation?

<p>Breast cancer (C)</p> Signup and view all the answers

What investigation finding is indicative of factor V and fibrinogen deficiency in disseminated intravascular coagulation?

<p>Prolongation of prothrombin time (A)</p> Signup and view all the answers

What is a major cause of morbidity in patients with recurrent bleeding due to hemophilia A?

<p>Joint damage (D)</p> Signup and view all the answers

Which exogenous cause can contribute to triggering disseminated intravascular coagulation?

<p>Snake venom (A)</p> Signup and view all the answers

What is the significance of increased D-dimer levels in the diagnosis of disseminated intravascular coagulation?

<p>Suggests excessive fibrinolysis (C)</p> Signup and view all the answers

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