Recurrent Bleeding in Severe Haemophilia

Play an AI-generated podcast conversation about this lesson

What is a long-term sequel of Hemophilia A?

Permanent damage to knee and elbow joints (correct)

Painless hematuria

Muscle atrophy

Thrombin time prolonged

What is the main characteristic feature of Hemophilia A?

GI bleeding

Painless hematuria

Bleeding into joints (correct)

Bleeding into muscles

Which diagnostic test for Hemophilia A is usually normal in count?

Prothrombin Time

Thrombin Time

Activated Partial Thromboplastin Time

Platelets count (correct)

What is a major morbidity associated with recurrent bleeding in individuals with severe hemophilia?

Deformities due to recurrent hemarthrosis Signup and view all the answers

Which complication can arise from muscle hematomas in individuals with hemophilia?

Muscle atrophy Signup and view all the answers

What is a typical clotting factor deficiency observed in Hemophilia A?

Factor VIII deficiency Signup and view all the answers

What is the major morbidity of recurrent bleeding in severe haemophilia?

Musculoskeletal complications Signup and view all the answers

Which joint is NOT typically affected by bleeding in severe haemophilia?

Wrists Signup and view all the answers

What happens if early treatment is not given to arrest bleeding in severe haemophilia?

Development of hot, swollen, and painful joint or muscle hematomas Signup and view all the answers

Which factor is raised by intravenous infusion of factor VIII concentrate in the treatment of bleeding episodes in severe haemophilia A?

Factor VIII Signup and view all the answers

What complication can arise from a large psoas bleed in patients with severe hemophilia?

Femoral nerve compression Signup and view all the answers

What is a potential complication of calf hematomas in patients with severe hemophilia?

Compartment syndrome Signup and view all the answers

What is a potential consequence of the depletion of haemostatic components in the context of disseminated intravascular coagulation?

Haemorrhagic state Signup and view all the answers

Which cancer type is NOT associated with causing disseminated intravascular coagulation?

Breast cancer Signup and view all the answers

What investigation finding is indicative of factor V and fibrinogen deficiency in disseminated intravascular coagulation?

Prolongation of prothrombin time Signup and view all the answers

What is a major cause of morbidity in patients with recurrent bleeding due to hemophilia A?

Joint damage Signup and view all the answers

Which exogenous cause can contribute to triggering disseminated intravascular coagulation?

Snake venom Signup and view all the answers

What is the significance of increased D-dimer levels in the diagnosis of disseminated intravascular coagulation?

Suggests excessive fibrinolysis Signup and view all the answers