Reactive Bone Formation in Musculoskeletal Tumors
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Questions and Answers

What type of bone formation results in layers of reactive bone resembling an onion skin?

  • Onion-skin (correct)
  • Codman's triangle
  • Sunburst reaction
  • Solid sunburst

    • Which type of periosteal reaction is associated with less malignant tumors?

  • Codman's triangle
  • Onion-skin (correct)
  • Sunburst reaction
  • Solid sunburst

    • Which term refers to successive waves of tumor expansion creating layers of reactive bone formation?

  • Sunburst reaction
  • Codman's triangle
  • Solid sunburst
  • Onion-skin (correct)

    • In Enneking's four questions, what process involves the formation of osteoid?

    <p>Chondroid process</p> Signup and view all the answers

    Which type of lesion may present with a radiolucent or ground glass appearance?

    <p>Matrix</p> Signup and view all the answers

    Which term is associated with a more malignant form of periosteal reaction?

    <p>Codman's triangle</p> Signup and view all the answers

    What is the male-to-female ratio for solitary osteochondroma?

    <p>2:1</p> Signup and view all the answers

    What is the morphology of osteochondromas?

    <p>Mushroom-shaped</p> Signup and view all the answers

    What is the composition of the outer layer of the head of an osteochondroma?

    <p>Hyaline cartilage</p> Signup and view all the answers

    In osteochondroma, what does the inner portion of the head and stalk predominantly consist of?

    <p>Newly formed bone</p> Signup and view all the answers

    At what age do patients with osteochondroma generally seek medical advice because of a bony mass?

    <p>2nd decade</p> Signup and view all the answers

    Why does activity-related pain occur in patients with osteochondroma?

    <p>Due to irritation of surrounding muscles by the mass</p> Signup and view all the answers

    What is the standard treatment for aneurysmal bone cyst (ABC) now?

    <p>Biopsy confirmation of diagnosis, staging studies, preoperative chemotherapy, surgical resection, postoperative chemotherapy</p> Signup and view all the answers

    What is a characteristic feature of aneurysmal bone cyst (ABC)?

    <p>Rapidly expansile lesion with multiple blood filled cystic cavities</p> Signup and view all the answers

    Before effective chemotherapy was developed, what was the survival outcome for patients with metastatic disease?

    <p>Approximately 80% of patients died of metastases</p> Signup and view all the answers

    What has increased the number of limb-sparing operations for osteosarcoma patients?

    <p>Improved reconstructive techniques</p> Signup and view all the answers

    What is the 5-year disease-free survival rate for individuals with stage II osteosarcoma?

    <p>Approximately 70%</p> Signup and view all the answers

    Where are chondrosarcomas commonly located?

    <p>Pelvis, shoulder, ribs</p> Signup and view all the answers

    Which age group has a peak incidence of primary chondrosarcomas?

    <p>Between 30 and 60 years old</p> Signup and view all the answers

    What is a common feature of secondary chondrosarcomas?

    <p>Association with previous osteochondroma</p> Signup and view all the answers

    How do low-grade chondrosarcomas often present radiographically?

    <p>Discrete radiolucent popcorn pattern</p> Signup and view all the answers

    What is a key factor influencing the incidence of distant metastases in chondrosarcoma?

    <p>Degree of malignancy</p> Signup and view all the answers

    Which common site is NOT mentioned as a frequent location for chondrosarcomas?

    <p>Distal extremities</p> Signup and view all the answers

    How is chondrosarcoma primarily treated?

    <p>Surgical resection</p> Signup and view all the answers

    What is the survival rate for patients without metastases?

    <p>70%</p> Signup and view all the answers

    Which liposarcoma subtype closely resembles lipoma but has a few spindle or stellate cells with hyperchromatic atypical nuclei and a high recurrence rate?

    <p>Well-differentiated lipoma-like liposarcoma</p> Signup and view all the answers

    In which age group is the peak incidence of liposarcoma?

    <p>50-60 years</p> Signup and view all the answers

    What distinguishes pleomorphic liposarcoma from other subtypes?

    <p>Poor prognosis and frequent metastases</p> Signup and view all the answers

    Where can leiomyosarcoma be found?

    <p>Mesentery, retroperitoneal space, skin, and wall of large veins</p> Signup and view all the answers

    Which characteristic is an indication of malignancy in leiomyoma?

    <p>Significant cellular pleomorphism</p> Signup and view all the answers

    What type of network of capillaries is seen in myxoid liposarcoma?

    <p>&quot;Chickenwire&quot; network</p> Signup and view all the answers

    Where is the site of subcutaneous tissue lipoma typically found?

    <p>Head and neck region</p> Signup and view all the answers

    "Early detection, proper techniques of diagnosis, and treatment can dramatically improve the chances of survival". Which statement best supports this claim?

    <p>&quot;Survival rate for patients without metastases is approximately 70%&quot;</p> Signup and view all the answers

    Which type of liposarcoma has small undifferentiated mesenchymal cells ad lipoblast set in a myxoid stroma?

    <p>Myxoid liposarcoma</p> Signup and view all the answers

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