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Questions and Answers
What is the therapeutic class of Ranitidine (Zantac)?
What is the pharmacologic class of Ranitidine (Zantac)?
What are the indications for Ranitidine (Zantac)?
Short term treatment of gastric and duodenal ulcers, prophylaxis of recurrent duodenal ulcers, treatment of Zollinger-Ellison syndrome and other hypersecretory states, GERD.
How does Ranitidine (Zantac) work?
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Which of the following are side effects of Ranitidine (Zantac)?
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What are some adverse drug interactions associated with Ranitidine (Zantac)?
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What patient teaching should be given for Ranitidine (Zantac)?
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What nursing implications should be monitored for patients on Ranitidine (Zantac)?
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Study Notes
Ranitidine (Zantac) Overview
- Ranitidine, commonly known as Zantac, is classified as an antiulcer drug.
- It functions as an H2 receptor antagonist, playing a crucial role in gastric acid secretion management.
Indications
- Used for short-term treatment of gastric and duodenal ulcers.
- Provides prophylaxis against recurrent duodenal ulcers.
- Treats Zollinger-Ellison syndrome and other hypersecretory states.
- Effective for managing gastroesophageal reflux disease (GERD).
Mechanism of Action
- Works by suppressing gastric acid secretion.
- Blocks histamine-2 receptors located on gastric parietal cells, reducing overall acid production.
Side Effects
- Potentially severe reactions include anaphylaxis and angioedema.
- May cause blurred vision and jaundice, along with general symptoms like headache, malaise, and vertigo.
- Can lead to elevation of gastric pH, impacting digestive processes.
Adverse Drug Interactions
- Co-administration with ketoconazole may decrease its concentration, reducing efficacy.
- Taking antacids concurrently can reduce the absorption of ranitidine.
- May interfere with warfarin's clearance, requiring careful monitoring and dosage adjustments.
Patient Teaching
- Patients should take ranitidine at bedtime for optimal results.
- It can be taken without regard to meals, enhancing adherence.
- Advising patients to avoid smoking can improve treatment outcomes.
Nursing Implications
- Assess for any signs of abdominal pain before administration.
- Monitor alanine aminotransferase (ALT) levels, especially in patients receiving high doses or prolonged IV therapy to prevent potential liver toxicity.
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Description
Test your knowledge of Ranitidine, commonly known as Zantac, an antiulcer drug. This quiz covers its indications, mechanism of action, side effects, and potential drug interactions. Gain a deeper understanding of how this medication manages gastric acid secretion and related conditions.
