Ranitidine (Zantac) Overview Quiz
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Questions and Answers

What is the therapeutic class of Ranitidine (Zantac)?

  • Antacid
  • Proton Pump Inhibitor
  • Antiulcer Drug (correct)
  • H2 Receptor Antagonist
  • What is the pharmacologic class of Ranitidine (Zantac)?

  • Proton Pump Inhibitor
  • Antacid
  • H2 Receptor Antagonist (correct)
  • Stimulating Hormone
  • What are the indications for Ranitidine (Zantac)?

    Short term treatment of gastric and duodenal ulcers, prophylaxis of recurrent duodenal ulcers, treatment of Zollinger-Ellison syndrome and other hypersecretory states, GERD.

    How does Ranitidine (Zantac) work?

    <p>Suppresses secretion of gastric acid by blocking histamine-2 receptors on gastric parietal cells.</p> Signup and view all the answers

    Which of the following are side effects of Ranitidine (Zantac)?

    <p>Blurred Vision</p> Signup and view all the answers

    What are some adverse drug interactions associated with Ranitidine (Zantac)?

    <p>Ketoconazole (may decrease concentration), antacids (reduce absorption), warfarin (may interfere with clearance).</p> Signup and view all the answers

    What patient teaching should be given for Ranitidine (Zantac)?

    <p>Take at bedtime for best results, take without regard to meals, avoid smoking.</p> Signup and view all the answers

    What nursing implications should be monitored for patients on Ranitidine (Zantac)?

    <p>Assess for abdominal pain, monitor ALT if on high doses or prolonged IV therapy.</p> Signup and view all the answers

    Study Notes

    Ranitidine (Zantac) Overview

    • Ranitidine, commonly known as Zantac, is classified as an antiulcer drug.
    • It functions as an H2 receptor antagonist, playing a crucial role in gastric acid secretion management.

    Indications

    • Used for short-term treatment of gastric and duodenal ulcers.
    • Provides prophylaxis against recurrent duodenal ulcers.
    • Treats Zollinger-Ellison syndrome and other hypersecretory states.
    • Effective for managing gastroesophageal reflux disease (GERD).

    Mechanism of Action

    • Works by suppressing gastric acid secretion.
    • Blocks histamine-2 receptors located on gastric parietal cells, reducing overall acid production.

    Side Effects

    • Potentially severe reactions include anaphylaxis and angioedema.
    • May cause blurred vision and jaundice, along with general symptoms like headache, malaise, and vertigo.
    • Can lead to elevation of gastric pH, impacting digestive processes.

    Adverse Drug Interactions

    • Co-administration with ketoconazole may decrease its concentration, reducing efficacy.
    • Taking antacids concurrently can reduce the absorption of ranitidine.
    • May interfere with warfarin's clearance, requiring careful monitoring and dosage adjustments.

    Patient Teaching

    • Patients should take ranitidine at bedtime for optimal results.
    • It can be taken without regard to meals, enhancing adherence.
    • Advising patients to avoid smoking can improve treatment outcomes.

    Nursing Implications

    • Assess for any signs of abdominal pain before administration.
    • Monitor alanine aminotransferase (ALT) levels, especially in patients receiving high doses or prolonged IV therapy to prevent potential liver toxicity.

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    Description

    Test your knowledge of Ranitidine, commonly known as Zantac, an antiulcer drug. This quiz covers its indications, mechanism of action, side effects, and potential drug interactions. Gain a deeper understanding of how this medication manages gastric acid secretion and related conditions.

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