Ran G-Protein Regulation

Cell bio bridges the molecular to the organismal level

Structure = function in the nucleus

Ran regulates protein transport by changing its conformation upon GTP hydrolysis, controlling the movement of proteins into and out of the nucleus

<p>Directed movement of proteins requires energy to increase order, similar to cleaning a room, and this energy is provided by GTP hydrolysis</p> Signup and view all the answers

<p>Importins regulate protein import into the nucleus, controlled by Ran, a small GTPase</p> Signup and view all the answers

<p>The release of proteins by exportins and importins is controlled by a small GTPase, Ran</p> Signup and view all the answers

<p>The concentration of Ran-GTP is higher in the nucleus than the cytoplasm, regulating protein transport</p> Signup and view all the answers

<p>Exportins regulate protein export out of the nucleus, controlled by Ran, a small GTPase</p> Signup and view all the answers

<p>GTP hydrolysis changes the conformation of Ran, regulating protein transport</p> Signup and view all the answers

<p>Compartmentalization is necessary for regulating protein transport, as it permits regulation in space and time</p> Signup and view all the answers