Raloxifene (Evista) Flashcards
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Questions and Answers

What is Raloxifene classified as?

  • Therapeutic class (correct)
  • Pharmacologic class (correct)
  • Medication administration
  • Pharmacologic action
  • What action does Raloxifene perform related to bone health?

    Decreases bone resorption and increases bone mass and density by acting through the estrogen receptor.

    What are the therapeutic uses of Raloxifene?

    Prevents osteoporosis in postmenopausal women, reduces serum total cholesterol and LDL, prevents breast cancer in postmenopausal women.

    What is the recommended dosage for Raloxifene medication administration?

    <p>PO: 60 mg/day</p> Signup and view all the answers

    Common complications of Raloxifene include ______.

    <p>hot flashes, leg cramps, weight gain, fever, arthralgia, depression, insomnia, chest pain, peripheral edema, decreased serum cholesterol, nausea, vomiting, flatulence, cystitis, migraines, flu-like symptoms, endometrial disorder, breast pain, vaginal bleeding, increases risk of VTE and stroke.</p> Signup and view all the answers

    What are the contraindications for Raloxifene?

    <p>Lactation and pregnancy, history of VTE, hypersensitivity.</p> Signup and view all the answers

    Important nursing interventions for Raloxifene include ______.

    <p>Assessing patient bone mineral density, monitoring patient labs, encouraging calcium supplement intake, patient/family education.</p> Signup and view all the answers

    What client education points should be emphasized for Raloxifene?

    <p>Take medication as directed, discontinue smoking and alcohol consumption, emphasize weight-bearing exercise, notify HCP if signs of VTE occur, may have teratogenic effects.</p> Signup and view all the answers

    What are some drug interactions with Raloxifene?

    <p>All of the above</p> Signup and view all the answers

    How is the effectiveness of Raloxifene medication evaluated?

    <p>Prevention of osteoporosis in postmenopausal women; reduced risk of breast cancer in postmenopausal women with osteoporosis and those at risk for invasive breast cancer.</p> Signup and view all the answers

    Study Notes

    Raloxifene (Evista) Overview

    • Used for the prevention of osteoporosis in postmenopausal women.
    • Classified as a selective estrogen receptor modulator (SERM).

    Pharmacologic Actions

    • Decreases bone resorption, enhancing bone mass and density.
    • Acts through the estrogen receptor to provide protective effects on bones.

    Therapeutic Uses

    • Prevents osteoporosis in postmenopausal women.
    • Reduces serum total cholesterol and low-density lipoproteins (LDL).
    • Offers protection against breast cancer in postmenopausal women.

    Dosage and Administration

    • Administered orally at a dosage of 60 mg per day.

    Complications and Side Effects

    • Common side effects include hot flashes, leg cramps, weight gain, and nausea among others.
    • May increase the risk of venous thromboembolism (VTE) and stroke.

    Contraindications

    • Not recommended for use in individuals with a history of VTE, during lactation and pregnancy, or those with hypersensitivity.

    Nursing Interventions

    • Assess patient bone mineral density to monitor effectiveness of treatment.
    • Regularly conduct laboratory tests to check for complications.
    • Encourage the intake of calcium supplements to support bone health.
    • Educate patients and their families on medication adherence and lifestyle modifications.

    Client Education

    • Instruct patients to take medication as prescribed and highlight the risks of smoking and alcohol use.
    • Emphasize the importance of weight-bearing exercises in maintaining bone health.
    • Advise to notify healthcare providers if signs of VTE develop, noting potential teratogenic effects.

    Drug Interactions

    • Interactions noted with warfarin, ampicillin, and cholestyramine, as well as highly protein-bound drugs.
    • Caution advised with herbal supplements like black cohosh.

    Evaluation of Medication Effectiveness

    • Effective in preventing osteoporosis in postmenopausal women.
    • Contributes to a reduced risk of breast cancer in those at risk, particularly in postmenopausal women with osteoporosis.

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    Description

    This quiz features key flashcards on Raloxifene, also known as Evista, focusing on its therapeutic classifications and pharmacologic actions. Each card presents essential terms and definitions related to its role in osteoporosis prevention and its impact on bone health in postmenopausal women.

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