Radiolabelling and Nuclear Imaging Quiz

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Questions and Answers

Which test is used to determine the radiochemical purity of a radiopharmaceutical?

  • Gel Chromatography
  • Paper and Instant Thin-Layer Chromatography (correct)
  • Solvent Extraction
  • Ion Exchange

What type of test is used to assess the sterility of a radiopharmaceutical?

  • Radio nuclidic Purity
  • Physicochemical Tests
  • Physical Characteristics
  • Biological Tests (correct)

Which technique is commonly used for determining the radio nuclidic purity of radiopharmaceuticals?

  • Toxicity
  • High-Performance Liquid Chromatography (HPLC) (correct)
  • Paper or Polyacrylamide Gel Electrophoresis
  • Distillation

Which term is used to describe a radioactive compound used to diagnose and treat human diseases?

<p>Radiopharmaceutical (B)</p> Signup and view all the answers

What is a key requirement for a radiopharmaceutical to be considered ideal for use?

<p>High target-to-non-target activity ratio (B)</p> Signup and view all the answers

Which mechanism plays a role in the localization of heat-damaged 99mTc-labeled red blood cells by the spleen?

<p>Passive diffusion (B)</p> Signup and view all the answers

Which oxidation state species do not readily form complexes with donor ligands or chelates?

<p>+7 (B)</p> Signup and view all the answers

What is the role of stannous chloride in the reduction process for 99mTc-based radiopharmaceuticals?

<p>Facilitating the reduction of technetium from its +7 oxidation state (C)</p> Signup and view all the answers

For which type of imaging is 99mTc-DTPA primarily used?

<p>Kidney imaging (D)</p> Signup and view all the answers

What metabolic pathway is normally operative in 18 F-Fludeoxyglucose (18F-FDG) metabolism?

<p>Glycolysis (D)</p> Signup and view all the answers

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