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Radiochemistry Lecture 7

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What is radiation?

Invisible energy waves or particles

What is radioactivity?

The property of some atoms to spontaneously give off energy by radioactive decay

What is the source of alpha particles?

Radioactive elements such as uranium, radium and polonium

What is the primary difference between X-rays and gamma rays?

Their origin within the atom

Why are alpha particles not a major concern for exposure to the outside of the body?

Because they lack the energy to penetrate even the outer layer of skin

What is an isotope?

Atoms of the same element that have the same number of protons

What is a major concern when working with gamma rays?

Their ability to pass through barriers

What is the process by which an atomic nucleus of an unstable atom loses energy?

Radioactive decay

What is the characteristic of the ionizations caused by alpha particles?

They are very close together

What is the purpose of radioisotopes in radiation therapy?

To destroy cancer cells

What type of radiation has enough energy to move atoms in a molecule around or cause them to vibrate?

Non-ionizing radiation

What is a potential negative effect of exposure to ionizing radiation?

Damage to cells and tissues

What is the charge of beta particles?

Negative

What is the effect of ionizing radiation on living things?

It poses a health risk by damaging tissue and DNA in genes

Why are beta particles less damaging to living tissue and DNA than alpha particles?

Because the ionizations they produce are more widely spaced

How are X-rays typically produced?

Through machine-generated electricity

What is the characteristics of gamma rays?

They are weightless packets of energy

What is the primary use of radioisotopes in medical imaging?

To visualize organ function

What is the emission of an alpha particle from an atomic nucleus?

Alpha radiation

When are gamma rays often emitted?

Along with alpha or beta particles during radioactive decay

What is a characteristic of gamma rays that makes them hazardous?

Their ability to pass through the human body

What is the composition of an alpha particle?

2 protons and 2 neutrons

What can stop beta particles?

A layer of clothing or a thin layer of a substance such as aluminum

What is a medical application of radiochemistry?

Medical imaging and diagnosis

What is one of the risks of contamination to human health?

Radiation exposure

What is the purpose of internal radiotherapy?

To treat cancer

How does radiotherapy destroy cancer cells?

By damaging the DNA

What is a common side effect of radiotherapy?

Damage to normal cells

Why is proper shielding important in radiochemistry research?

To prevent radiation exposure

What is the goal of radiation safety guidelines?

To mitigate occupational hazards

Study Notes

Radiation and Radioactivity

  • Radiation: invisible energy waves or particles that can come from unstable atoms or be produced by machines
  • Radioactivity: property of some atoms to spontaneously give off energy by emitting ionizing particles

Isotopes and Radioactive Decay

  • Isotopes: atoms of the same element with the same number of protons but a different number of neutrons
  • Radioactive decay: process by which an atomic nucleus of an unstable atom loses energy by emitting ionizing particles

Types of Radiation

  • Non-Ionizing Radiation: enough energy to move atoms in a molecule or cause them to vibrate, but not enough to remove electrons from atoms (examples: radio waves, visible light, microwaves)
  • Ionizing Radiation: has enough energy to knock electrons out of atoms, posing a health risk by damaging tissue and DNA in genes (examples: x-ray machines, cosmic particles, radioactive elements)

Types of Ionizing Radiation

  • Alpha (α) Radiation:
    • Emission of an alpha particle (2 protons and 2 neutrons) from an atomic nucleus
    • Decreases atomic mass by 4 units and atomic number by 2
    • Positively charged and made up of two protons and two neutrons from the atom's nucleus
    • Can cause damage to sensitive living tissue, especially if inhaled or ingested
  • Beta (β) Particles:
    • Small, fast-moving particles with a negative electrical charge
    • Emitted from an atom's nucleus during radioactive decay
    • More penetrating than alpha particles but less damaging to living tissue and DNA
    • Can cause skin burns and damage if inhaled or ingested
  • Gamma (γ) Rays:
    • Weightless packets of energy called photons
    • Pure energy with no mass
    • Similar to visible light but with higher energy
    • Can easily penetrate barriers and cause ionizations that damage tissue and DNA
  • X-Rays:
    • Similar to gamma rays but with lower energy and less penetrating
    • Emitted from processes outside the nucleus
    • Can be produced naturally or by machines using electricity

Medical Uses of Radiochemistry

  • Medical Imaging and Diagnosis: radioisotopes used in PET and SPECT to detect and diagnose diseases
  • Radiation Therapy: radioisotopes and radiation sources used to treat cancer
  • Nuclear Medicine: radioisotopes used for diagnostic and therapeutic purposes to visualize and evaluate organ function

Potential Negative Effects and Risks

  • Exposure to ionizing radiation can cause acute or long-term health effects, including cancer and genetic mutations
  • Contamination and environmental impact: air, soil, and water contamination can persist and pose risks to human health and ecosystems
  • Occupational hazards: workers involved in radiochemistry research or nuclear facilities may face radiation exposure risks

Radiotherapy

  • Use of radiation, usually x-rays, to treat cancer
  • Can be used to treat cancer, reduce the chance of cancer coming back, and relieve symptoms
  • Can be used alone or with other treatments, such as chemotherapy or surgery
  • Works by destroying cancer cells in the treated area by damaging the DNA, but also affects normal cells and can cause side effects

Introduction to radiation and radioactivity, including the properties of atoms and radioactive decay, as part of a medical chemistry course.

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