Radioactive Decay and Half-Life

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Questions and Answers

What is the physical half-life of a radionuclide?

  • The time taken for its activity to decay to one-quarter of its original value
  • The time taken for its activity to decay to three-quarters of its original value
  • The time taken for its activity to decay to zero
  • The time taken for its activity to decay to half of its original value (correct)

What happens to the number of radioactive nuclei over time?

  • It decreases exponentially (correct)
  • It remains constant
  • It fluctuates randomly
  • It increases exponentially

How many half-lives does it take to reduce the activity of a radionuclide by a factor of 1000?

  • 5
  • 20
  • 10 (correct)
  • 15

What is the effect of heat, pressure, electricity, or chemical reactions on the physical half-life?

<p>It has no effect on the physical half-life (A)</p> Signup and view all the answers

What happens to the number of radioactive nuclei in two successive half-lives?

<p>It decreases to one-quarter of its original value (C)</p> Signup and view all the answers

What is the shape of the graph of the number of nuclei present as a function of time?

<p>Exponential (C)</p> Signup and view all the answers

What is a characteristic of the physical half-life?

<p>It is a fixed characteristic of the radionuclide (D)</p> Signup and view all the answers

What is the range of physical half-life of radionuclides?

<p>From fractions of a second to millennia (A)</p> Signup and view all the answers

Which radionuclide has a physical half-life of 67 hours?

<p>Molybdenum-99 (D)</p> Signup and view all the answers

What is the term for the pharmaceutical that has been labelled with a radionuclide?

<p>Radiopharmaceutical (B)</p> Signup and view all the answers

What is the biological half-life of a pharmaceutical referring to?

<p>The rate of elimination from the body (D)</p> Signup and view all the answers

Why do radionuclides form part of a salt or organic compound in medical imaging?

<p>To ensure they concentrate in the tissues or organ of interest (A)</p> Signup and view all the answers

What is the term for the time it takes for the concentration of a radionuclide to decrease by half in the body?

<p>Effective half-life (B)</p> Signup and view all the answers

What happens to a radiopharmaceutical when it is administered alone?

<p>It is gradually eliminated from the body by metabolic processes (D)</p> Signup and view all the answers

What determines the decay of radioactivity in a specific tissue or organ when a radiopharmaceutical is administered to a patient?

<p>Both the physical half-life and the metabolic turnover and excretion of the radiopharmaceutical (C)</p> Signup and view all the answers

What is the relationship between the effective half-life and the physical and biological half-lives?

<p>teff &lt; tbiol, tphys (D)</p> Signup and view all the answers

What is a desirable property of a radionuclide for imaging?

<p>A physical half-life of a few hours (B)</p> Signup and view all the answers

What is the significance of the daughter nuclide in a radiopharmaceutical?

<p>It should have a very long half-life (D)</p> Signup and view all the answers

Why is it important to consider the disease state of the patient when using radiopharmaceuticals?

<p>It affects the effective half-life of the radiopharmaceutical (D)</p> Signup and view all the answers

What happens if the physical half-life of a radionuclide is too short?

<p>Too much activity is prepared (C)</p> Signup and view all the answers

What is the relationship between the effective half-life and the physical and biological half-lives in terms of their reciprocals?

<p>1/teff = 1/tbiol + 1/tphys (A)</p> Signup and view all the answers

What type of radiation is desirable for imaging due to its ability to exit the patient?

<p>Gamma rays (D)</p> Signup and view all the answers

What is the ideal energy range of gamma rays for imaging?

<p>50-300 keV (C)</p> Signup and view all the answers

What property of gamma rays is useful for eliminating scattered radiation?

<p>Monoenergetic (D)</p> Signup and view all the answers

Why is it important for a radionuclide to be easily attached to a pharmaceutical at room temperature?

<p>To prevent its metabolism (D)</p> Signup and view all the answers

What is a desirable property of a radionuclide for imaging in terms of availability?

<p>Readily available at the hospital site (B)</p> Signup and view all the answers

What is the significance of high specific activity in a radionuclide?

<p>It reduces the dose to the patient (C)</p> Signup and view all the answers

What is a desirable property of a radiopharmaceutical in terms of localization?

<p>It localizes largely and quickly in the target tissue (B)</p> Signup and view all the answers

Why is it important for a radiopharmaceutical to have a low toxicity?

<p>To minimize its side effects (D)</p> Signup and view all the answers

What is a desirable property of a radiopharmaceutical in terms of elimination?

<p>It is eliminated quickly from the body (C)</p> Signup and view all the answers

What is a desirable property of a radiopharmaceutical in terms of stability?

<p>It forms a stable product both in vitro and in vivo (A)</p> Signup and view all the answers

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