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Neurogenesis, neuronal survival, circuit formation and basic anatomy

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Questions and Answers

What does neurogenesis entail?

Mitotic divisions of neuroblasts and stem cells from ventricular and marginal layers, that differentiate into neurones and migrate to different areas

What does the dynamic growth cone do?

Guides extension of cell body
Guides extension of synapse
Guides extension of dendrites and axons (correct)
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What are the structures of the dynamic growth cone?

Lamellipodia and filopodia

What are the actin components in the dynamic growth cone?

G-actin and F-actin Signup and view all the answers

What are the microtubule components of the dynamic growth cone?

Tubulin (A) Signup and view all the answers

What does the polymerisation/depolymerisation of actin do for the dynamic growth cone?

Direction of the growth cone (B) Signup and view all the answers

An example of chemoattractants in long-range cues?

Netrins (C) Signup and view all the answers

An example of chemorepulsions in long-range cues?

Semaphorins (D) Signup and view all the answers

What is NOT a neurotrophin that induces neurones to live?

Semaphorins (C) Signup and view all the answers

Where does synaptic pruning occur in the PNS and CNS?

PNS - Neuromuscular junctions, CNS - Cerebellum Signup and view all the answers