12 Questions
What does neurogenesis entail?
Mitotic divisions of neuroblasts and stem cells from ventricular and marginal layers, that differentiate into neurones and migrate to different areas
What does the dynamic growth cone do?
Guides extension of dendrites and axons
What are the structures of the dynamic growth cone?
Lamellipodia and filopodia
What are the actin components in the dynamic growth cone?
G-actin and F-actin
What are the microtubule components of the dynamic growth cone?
Tubulin
What does the polymerisation/depolymerisation of actin do for the dynamic growth cone?
Direction of the growth cone
An example of chemoattractants in long-range cues?
Netrins
An example of chemorepulsions in long-range cues?
Semaphorins
What is NOT a neurotrophin that induces neurones to live?
Semaphorins
Where does synaptic pruning occur in the PNS and CNS?
PNS - Neuromuscular junctions, CNS - Cerebellum
An example of contact attractants in short-range cues?
Cadherins
What is an example of contact repulsions of short-range cues?
Ephrins
Test your knowledge of neurogenesis and the structures of the dynamic growth cone. Explore the actin and microtubule components, as well as the roles of polymerisation and depolymerisation of actin in the dynamic growth cone.
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