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Questions and Answers

  1. Which rapid-acting insulin has a peak time of 1-1.5 hours

  • Lispro (correct)
  • Glargine

  1. What is the primary concern when giving metformin to a patient receiving contrast dye

  • Lactic acidosis (correct)
  • B12 deficiency

  1. Which mnemonic helps remember rapid-acting insulins?

  • "Regular and Short"
  • "Do not LAG" LAG stands for Lispro, Aspart, and Glulisine - the three rapid-acting insulins. (correct)

  1. How long do long-acting insulins typically last?

<p>24 hours (A)</p> Signup and view all the answers

  1. Which adverse effect is associated with SGLT2 inhibitors?

<p>Urinary tract infections Correct (B)</p> Signup and view all the answers

  1. What is the duration of action for NPH insulin?

<p>10-16 (A)</p> Signup and view all the answers

  1. Which adverse effect is most concerning with Thiazolidinediones?

<p>Heart failure (B)</p> Signup and view all the answers

  1. What is the mechanism of sulfonylureas?

<p>Increase insulin release (B)</p> Signup and view all the answers

  1. Which medication requires B12 monitoring?

<p>Metformin (A)</p> Signup and view all the answers

  1. What is the mechanism of alpha-glucosidase inhibitors

<p>Inhibit intestinal enzyme (A)</p> Signup and view all the answers

  1. How do GLP-1 agonists work?

<p>Potentiate insulin release (B)</p> Signup and view all the answers

  1. Which medication ends in "-gliptIn"?

<p>Sitagliptin (A)</p> Signup and view all the answers

  1. When should metformin be held?

<p>Before contrast studies (A)</p> Signup and view all the answers

  1. Which drug class causes pancreatitis?

<p>GLP-1 agonists (A)</p> Signup and view all the answers

  1. What is the duration of rapid-acting insulins?

<p>3-4 hours (A)</p> Signup and view all the answers

  1. What unique side effect do SGLT2 inhibitors cause?

<p>Glucosuria (B)</p> Signup and view all the answers

  1. Which medication works through PPAR-gamma?

<p>Pioglitazone (A)</p> Signup and view all the answers

  1. What is the mnemonic for GLP-1 agonists?

<p>&quot;Gulping down TIDE&quot; (B)</p> Signup and view all the answers

  1. Which insulin has no peak time?

<p>Glargine (A)</p> Signup and view all the answers

  1. What is the first-line oral medication for Type 2 diabetes?

<p>Metformin (B)</p> Signup and view all the answers

  1. Which medication requires monitoring for bone fractures?

<p>Pioglitazone (B)</p> Signup and view all the answers

  1. What is the primary mechanism of metformin

<p>Inhibits hepatic gluconeogenesis (A)</p> Signup and view all the answers

  1. Which class of medications ends in "-flozin"?

<p>SGLT2 inhibitors (B)</p> Signup and view all the answers

  1. What adverse effect is associated with alpha-glucosidase inhibitors

<p>GI upset and bloating (A)</p> Signup and view all the answers

  1. Which medication is a synthetic amylin?

<p>Pramlintide (A)</p> Signup and view all the answers

  1. What is the peak time for regular insulin?

<p>2.5 hours (B)</p> Signup and view all the answers

  1. Which drug class requires monitoring for respiratory infections?

<p>DPP-4 inhibitors (A)</p> Signup and view all the answers

  1. What is the mnemonic for NPH insulin?

<p>&quot;Not Particularly Hasty&quot; (B)</p> Signup and view all the answers

  1. Which medication can cause disulfiram reaction?

<p>Sulfonylureas (A)</p> Signup and view all the answers

  1. When does rapid-acting insulin peak?

<p>1-1.5 hours (A)</p> Signup and view all the answers

  1. Which medication works in the proximal tubule?

<p>Metformin (A)</p> Signup and view all the answers

  1. What characterizes long-acting insulin?

<p>No peak time (A)</p> Signup and view all the answers

  1. Which drug requires monitoring for heart failure?

<p>Rosiglitazone (A)</p> Signup and view all the answers

  1. What distinguishes GLP-1 agonists from DPP-4 inhibitors?

<p>Route of administration (A)</p> Signup and view all the answers

  1. When should sulfonylureas be used with caution?

<p>Elderly patients (A)</p> Signup and view all the answers

  1. What is the primary action of GLP-1

<p>Promotes insulin release (B)</p> Signup and view all the answers

When is metformin contraindicated?

<p>Severe renal impairment (A)</p> Signup and view all the answers

  1. Which drug class works through nuclear receptors

<p>Thiazolidinediones (B)</p> Signup and view all the answers

  1. What is the common side effect of SGLT2 inhibitors?

<p>Dehydration (B)</p> Signup and view all the answers

  1. How do meglitinides differ from sulfonylureas?

<p>Duration of action (A)</p> Signup and view all the answers

  1. Which insulin type is best for basal coverage

<p>Glargine Correct (B)</p> Signup and view all the answers

  1. What monitoring is needed with DPP-4 inhibitors?

<p>Renal function (A)</p> Signup and view all the answers

  1. How does acarbose work?

<p>Delays carbohydrate digestion (B)</p> Signup and view all the answers

  1. What is a risk of TZD use?

<p>Bone Loss (@)</p> Signup and view all the answers

  1. Which medication requires contrast precautions?

<p>Metformin (B)</p> Signup and view all the answers

  1. When is NPH insulin most likely to peak?

<p>8 hours (A)</p> Signup and view all the answers

  1. Which medication requires frequent urinary infection monitoring?

<p>Canagliflozin (A)</p> Signup and view all the answers

  1. What is the primary action of DPP-4 inhibitors

<p>Prevent GLP-1 breakdown (B)</p> Signup and view all the answers

  1. Which drug class requires fracture risk monitoring?

<p>Thiazolidinediones (B)</p> Signup and view all the answers

  1. What is the duration of regular insulin?

<p>4-6 hours (A)</p> Signup and view all the answers

  1. Which medication works by blocking intestinal enzymes?

<p>Acarbose (A)</p> Signup and view all the answers

  1. What characterizes rapid-acting insulins?

<p>Quick peak (B)</p> Signup and view all the answers

  1. Which side effect is associated with GLP-1 agonists

<p>Pancreatitis (A)</p> Signup and view all the answers

  1. What is the key benefit of long-acting insulin?

<p>Basal coverage (B)</p> Signup and view all the answers

  1. What determines SGLT2 inhibitor dosing?

<p>Renal function (B)</p> Signup and view all the answers

  1. Which medication increases insulin sensitivity?

<p>Pioglitazone (A)</p> Signup and view all the answers

  1. What is a contraindication for TZDs?

<p>) Heart failure (A)</p> Signup and view all the answers

  1. When should Glargine be administered?

<p>Same time daily (A)</p> Signup and view all the answers

  1. Which drug requires close potassium monitoring?

<p>Empagliflozin (A)</p> Signup and view all the answers

  1. What is the primary mechanism of sulfonylureas?

<p>Stimulates insulin release (B)</p> Signup and view all the answers

  1. When should alpha-glucosidase inhibitors be taken?

<p>With meals (A)</p> Signup and view all the answers

  1. Which medication requires monitoring for yeast infections?

<p>Dapagliflozin (A)</p> Signup and view all the answers

  1. What is the benefit of GLP-1 agonists?

<p>Weight loss (A)</p> Signup and view all the answers

  1. Which insulin is best for correcting glucose?

<p>Lispro (B)</p> Signup and view all the answers

  1. Which medication can cause lactic acidosis?

<p>Metformin (A)</p> Signup and view all the answers

  1. What is the timing for NPH insulin peak?

<p>8 hours (B)</p> Signup and view all the answers

  1. How do DPP-4 inhibitors affect GLP-1?

<p>Prevent breakdown (B)</p> Signup and view all the answers

  1. When are SGLT2 inhibitors contraindicated?

<p>Severe renal failure (A)</p> Signup and view all the answers

  1. What is the mnemonic for DPP-4 inhibitors?

<p>&quot;Lipton makes you PP-4&quot; (B)</p> Signup and view all the answers

  1. Which insulin provides 24-hour coverage?

<p>Glargine (B)</p> Signup and view all the answers

  1. What is a side effect of TZDs?

<p>Bone fractures (A)</p> Signup and view all the answers

  1. When should sulfonylureas be taken?

<p>With meals (A)</p> Signup and view all the answers

  1. Which drug increases peripheral glucose uptake?

<p>Metformin (A)</p> Signup and view all the answers

  1. What is the primary concern with elderly patients on sulfonylureas?

<p>Hypoglycemia (B)</p> Signup and view all the answers

  1. Which medication inhibits hepatic gluconeogenesis?

<p>Metformin (A)</p> Signup and view all the answers

  1. What characterizes SGLT2 inhibitor action?

<p>Glucose excretion (B)</p> Signup and view all the answers

  1. When do rapid-acting insulins peak?

<p>1-1.5 hours (A)</p> Signup and view all the answers

  1. Which medication works through PPAR-gamma?

<p>Rosiglitazone (A)</p> Signup and view all the answers

  1. Which drug requires heart failure monitoring?

<p>Pioglitazone (A)</p> Signup and view all the answers

  1. When should long-acting insulin be given?

<p>Same time daily (B)</p> Signup and view all the answers

  1. What is the mnemonic for sulfonylureas

<p>&quot;IDE&quot; take your sulfonylurea&quot; (B)</p> Signup and view all the answers

  1. When is metformin discontinued?

<p>Severe renal failure (A)</p> Signup and view all the answers

  1. What is pramlintide's mechanism?

<p>Synthetic amylin (B)</p> Signup and view all the answers

  1. When do alpha-glucosidase inhibitors work?

<p>Intestinal absorption (A)</p> Signup and view all the answers

  1. Which medication requires UTI monitoring?

<p>Empagliflozin (A)</p> Signup and view all the answers

  1. Which drug acts on the potassium channel?

<p>Nateglinide (A)</p> Signup and view all the answers

  1. What distinguishes NPH insulin?

<p>8-hour peak (A)</p> Signup and view all the answers

  1. When monitoring TZDs, what's crucial?

<p>Heart failure (B)</p> Signup and view all the answers

  1. What characterizes GLP-1 agonists?

<p>Injectable (A)</p> Signup and view all the answers

  1. Which causes hyperkalemia risk

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

  1. What is metformin's key monitoring requirement?

<p>Renal function (A)</p> Signup and view all the answers

  1. Which insulin is best for meals?

<p>Lispro Rationale (B)</p> Signup and view all the answers

  1. What defines GLP-1 action?

<p>Insulin release (A)</p> Signup and view all the answers

  1. When do DPP-4 inhibitors need dose adjustment?

<p>Renal impairment (A)</p> Signup and view all the answers

  1. Which medication delays carb absorption.

<p>Acarbose (A)</p> Signup and view all the answers

  1. What's a unique side effect of SGLT2 inhibitors?

<p>Yeast infections (B)</p> Signup and view all the answers

  1. How long does regular insulin last?

<p>4-6 hours (A)</p> Signup and view all the answers

  1. Which drug increases insulin sensitivity

<p>Rosiglitazone (A)</p> Signup and view all the answers

  1. When do meglitinides peak?

<p>1 hour (A)</p> Signup and view all the answers

  1. What's the key effect of GLP-1 agonists?

<p>Weight loss (B)</p> Signup and view all the answers

  1. Which requires bone health monitoring?

<p>Pioglitazone (B)</p> Signup and view all the answers

  1. What's metformin's effect on B12?

<p>Deficiency (A)</p> Signup and view all the answers

  1. What's SGLT2 inhibitors' action site?

<p>Kidney (B)</p> Signup and view all the answers

  1. What's the main GI side effect of acarbose

<p>Bloating (B)</p> Signup and view all the answers

  1. What causes disulfiram reaction?

<p>Sulfonylureas (A)</p> Signup and view all the answers

  1. Why monitor potassium with SGLT2?

<p>Risk of hyperkalemia (B)</p> Signup and view all the answers

  1. Which affects glucose uptake?

<p>Metformin (A)</p> Signup and view all the answers

  1. When to check B12 with metformin?

<p>Annually (A)</p> Signup and view all the answers

  1. Which works on nuclear receptors?

<p>DPP-4 inhibitors (B)</p> Signup and view all the answers

  1. What's unique about pramlintide?

<p>Amylin analog (A)</p> Signup and view all the answers

  1. Which requires rapid discontinuation if heart failure?

<p>Pioglitazone (A)</p> Signup and view all the answers

  1. What causes respiratory infections risk?

<p>DPP-4 inhibitors (A)</p> Signup and view all the answers

  1. When to give mealtime insulin?

<p>15 minutes (A)</p> Signup and view all the answers

  1. What timing for NPH peak?

<p>8 hours (A)</p> Signup and view all the answers

  1. Which causes dehydration risk?

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

  1. When to monitor for pancreatitis?

<p>GLP-1 agonists (A)</p> Signup and view all the answers

  1. What's TZD monitoring priority?

<p>Heart failure (A)</p> Signup and view all the answers

  1. Which requires UTI prevention?

<p>Dapagliflozin (A)</p> Signup and view all the answers

  1. When to stop metformin?

<p>eGFR &lt; 30 (A)</p> Signup and view all the answers

  1. Which causes fracture risk?

<p>TZDs (A)</p> Signup and view all the answers

  1. What's alpha-glucosidase timing?

<p>With meals (A)</p> Signup and view all the answers

  1. What's the evening insulin timing?

<p>Same time (B)</p> Signup and view all the answers

  1. Which needs fluid monitoring?

<p>Pioglitazone (A)</p> Signup and view all the answers

  1. What's sulfonylurea peak?

<p>2-3 hours (B)</p> Signup and view all the answers

  1. When to check ketones?

<p>High glucose (A)</p> Signup and view all the answers

  1. Which affects GLP-1 levels?

<p>DPP-4 inhibitors (A)</p> Signup and view all the answers

  1. When does lactic acidosis risk increase?

<p>Renal failure (A)</p> Signup and view all the answers

  1. What's unique about glargine?

<p>No peak (A)</p> Signup and view all the answers

  1. What affects SGLT2 dosing?

<p>Renal function (B)</p> Signup and view all the answers

  1. Which causes weight loss?

<p>GLP-1 agonists (A)</p> Signup and view all the answers

  1. What's most important in DKA?

<p>Fluids (B)</p> Signup and view all the answers

  1. Which blocks carb absorption?

<p>Acarbose (A)</p> Signup and view all the answers

  1. What's TZD contraindication?

<p>Heart failure (A)</p> Signup and view all the answers

  1. Which requires potassium monitoring?

<p>SGLT2 inhibitors (A)</p> Signup and view all the answers

  1. What's GLP-1 effect?

<p>Slows digestion (A)</p> Signup and view all the answers

  1. Which needs bone monitoring?

<p>TZDs (A)</p> Signup and view all the answers

  1. What causes yeast infections?

Signup and view all the answers

  1. When to check ketones?

<p>Blood sugar &gt;250 (A)</p> Signup and view all the answers

  1. Which has infection risk?

<p>Dapagliflozin (A)</p> Signup and view all the answers

  1. What's NPH duration?

<p>10-16 hours (A)</p> Signup and view all the answers

  1. Which affects glucagon?

<p>GLP-1 agonists (A)</p> Signup and view all the answers

  1. What's metformin's primary action?

<p>Hepatic glucose (A)</p> Signup and view all the answers

  1. When to hold TZDs?

<p>Heart failure (A)</p> Signup and view all the answers

  1. Which causes B12 issues?

<p>Metformin (A)</p> Signup and view all the answers

  1. What's SGLT2 mechanism?

<p>Kidney excretion (A)</p> Signup and view all the answers

  1. What's elderly sulfonylurea risk?

<p>Hypoglycemia (B)</p> Signup and view all the answers

  1. What's acarbose timing?

<p>With meals (A)</p> Signup and view all the answers

Signup and view all the answers

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