Pyruvate Dehydrogenase Complex (PDH) Quiz

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Questions and Answers

Which enzyme in the Pyruvate Dehydrogenase Complex catalyzes the conversion of pyruvate to Acetyl CoA?

Pyruvate E2
Dihydrolipoyl Dehydrogenase
E1
Dihydrolipoyl Transacetylase (correct)

What is the advantage of having the Pyruvate Dehydrogenase Complex made up of multiple enzymes instead of just one?

Ability to catalyze multiple reactions concurrently (correct)
Increased specificity in substrate binding
Easier regulation of enzyme activity
Reduced need for cofactors

Which of the following is NOT a cofactor required by the Pyruvate Dehydrogenase Complex?

Lipoic Acid
Thiamine Pyrophosphate (TPP)
FAD (flavin adenine dinucleotide)
Ribonucleic Acid (RNA) (correct)

What type of reaction is catalyzed by the Pyruvate Dehydrogenase Complex?

Irreversible (B) Signup and view all the answers

Which molecule is produced as a product of the Pyruvate Dehydrogenase Complex besides Acetyl CoA?

CO2 (C) Signup and view all the answers

What is the function of the Dihydrolipoyl Dehydrogenase enzyme in the Pyruvate Dehydrogenase Complex?

Regenerating enzyme activity in E1 after each cycle (D) Signup and view all the answers

What is the function of Acetyl CoA in metabolism?

Energy production (C) Signup and view all the answers

Which chapter in the course material covers the Pyruvate Dehydrogenase complex?

Chapter 18 (C) Signup and view all the answers

How many stages are involved in cellular respiration according to the text?

3 (D) Signup and view all the answers

Which component is described as the 'energy currency' in the text?

Adenosine Triphosphate (ATP) (A) Signup and view all the answers

What does the Pyruvate Dehydrogenase complex (PDH) prepare for?

Citric Acid Cycle (A) Signup and view all the answers

Which biomolecule is NOT mentioned as a component of ATP in the text?

Thymine (A) Signup and view all the answers

Which metabolic process involves oxidative phosphorylation?

Citric Acid Cycle (B) Signup and view all the answers

What is Acetyl CoA's role in relation to biomolecules?

Transportation (C) Signup and view all the answers

Which molecule serves as a transient carbon carrier in the Pyruvate Dehydrogenase Complex?

Thiamine Pyrophosphate (TPP) (A) Signup and view all the answers

What is the role of Lipoic Acid in the Pyruvate Dehydrogenase Complex?

Carries electrons and acyl groups (A) Signup and view all the answers

Which vitamin is thiamine pyrophosphate (TPP) derived from?

Vitamin B1 (thiamine) (C) Signup and view all the answers

What is the advantage of using a protein complex like the Pyruvate Dehydrogenase Complex?

Increases the rate of reaction due to high enzyme concentrations (B) Signup and view all the answers

Which subunit of the Pyruvate Dehydrogenase Complex is associated with a lipoyl group?

E2 (D) Signup and view all the answers

What is the main function of Coenzyme A/Acetyl Coenzyme A in cellular respiration?

Carries electrons and acyl groups (C) Signup and view all the answers

Why is substrate channeling advantageous in enzymatic reactions like those in the Pyruvate Dehydrogenase Complex?

Increases the local concentration of products (B) Signup and view all the answers

Flashcards

Dihydrolipoyl Transacetylase

Catalyzes the transfer of the acetyl group from lipoamide to Coenzyme A, forming Acetyl CoA.

Advantage of Multiple Enzymes in PDH Complex?

Multiple enzymes allow for concurrent reactions.