21 Questions
Which enzyme in the Pyruvate Dehydrogenase Complex catalyzes the conversion of pyruvate to Acetyl CoA?
Dihydrolipoyl Transacetylase
What is the advantage of having the Pyruvate Dehydrogenase Complex made up of multiple enzymes instead of just one?
Ability to catalyze multiple reactions concurrently
Which of the following is NOT a cofactor required by the Pyruvate Dehydrogenase Complex?
Ribonucleic Acid (RNA)
What type of reaction is catalyzed by the Pyruvate Dehydrogenase Complex?
Irreversible
Which molecule is produced as a product of the Pyruvate Dehydrogenase Complex besides Acetyl CoA?
CO2
What is the function of the Dihydrolipoyl Dehydrogenase enzyme in the Pyruvate Dehydrogenase Complex?
Regenerating enzyme activity in E1 after each cycle
What is the function of Acetyl CoA in metabolism?
Energy production
Which chapter in the course material covers the Pyruvate Dehydrogenase complex?
Chapter 18
How many stages are involved in cellular respiration according to the text?
3
Which component is described as the 'energy currency' in the text?
Adenosine Triphosphate (ATP)
What does the Pyruvate Dehydrogenase complex (PDH) prepare for?
Citric Acid Cycle
Which biomolecule is NOT mentioned as a component of ATP in the text?
Thymine
Which metabolic process involves oxidative phosphorylation?
Citric Acid Cycle
What is Acetyl CoA's role in relation to biomolecules?
Transportation
Which molecule serves as a transient carbon carrier in the Pyruvate Dehydrogenase Complex?
Thiamine Pyrophosphate (TPP)
What is the role of Lipoic Acid in the Pyruvate Dehydrogenase Complex?
Carries electrons and acyl groups
Which vitamin is thiamine pyrophosphate (TPP) derived from?
Vitamin B1 (thiamine)
What is the advantage of using a protein complex like the Pyruvate Dehydrogenase Complex?
Increases the rate of reaction due to high enzyme concentrations
Which subunit of the Pyruvate Dehydrogenase Complex is associated with a lipoyl group?
E2
What is the main function of Coenzyme A/Acetyl Coenzyme A in cellular respiration?
Carries electrons and acyl groups
Why is substrate channeling advantageous in enzymatic reactions like those in the Pyruvate Dehydrogenase Complex?
Increases the local concentration of products
Test your knowledge on the Pyruvate Dehydrogenase Complex (PDH) which catalyzes the synthesis of Acetyl-CoA in the mitochondria. Learn about the reactions involved and the advantages of using a protein complex in this process.
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