Pyogenic Osteomyelitis Quiz
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Questions and Answers

What is a significant complication of chronic osteomyelitis?

  • Improved bone density
  • Immediate healing
  • Acute pain
  • Pathologic fracture (correct)

Which of the following correctly describes Brodie's abscess?

  • It is an acute form of osteomyelitis.
  • It is located in the metaphysis of a long bone. (correct)
  • It appears as a large bulging lesion.
  • It is usually found in the diaphysis of a long bone.

Which of these complications is associated with chronic osteomyelitis?

  • Bone regeneration
  • Muscle hypertrophy
  • Sepsis (correct)
  • Increase in cartilage

What characteristic does a Brodie's abscess exhibit on an X-ray?

<p>Small area of radiopacity (B)</p> Signup and view all the answers

Which of the following is NOT a complication of chronic osteomyelitis?

<p>Acute inflammation (D)</p> Signup and view all the answers

What is the primary location of Brodie's abscess within a bone?

<p>Metaphysis (C)</p> Signup and view all the answers

What aspect is true about Brodie's abscess compared to acute osteomyelitis?

<p>Brodie's abscess is a subacute form of osteomyelitis. (A)</p> Signup and view all the answers

Which condition may arise from chronic osteomyelitis affecting the draining sinus tract?

<p>Squamous cell carcinoma (B)</p> Signup and view all the answers

Which age group accounts for the majority of acute pyogenic osteomyelitis cases?

<p>Children and adolescents (D)</p> Signup and view all the answers

In children, which part of the bone is commonly affected by acute pyogenic osteomyelitis?

<p>Metaphysis (D)</p> Signup and view all the answers

What is the first stage of the disease process in acute pyogenic osteomyelitis?

<p>Inflammation (D)</p> Signup and view all the answers

What condition develops when pus breaks through the skin during acute pyogenic osteomyelitis?

<p>Abscess formation (B)</p> Signup and view all the answers

What leads to the formation of a sequestrum in the context of acute pyogenic osteomyelitis?

<p>Bone necrosis (A)</p> Signup and view all the answers

In adults, which area of the bone is more likely to be affected by acute pyogenic osteomyelitis?

<p>Epiphysis and subchondral regions (C)</p> Signup and view all the answers

During which stage of acute pyogenic osteomyelitis does new bone formation occur?

<p>Involucrum (D)</p> Signup and view all the answers

What might occur if acute pyogenic osteomyelitis does not resolve?

<p>Further complications (D)</p> Signup and view all the answers

Which structure is highlighted during the initial stage of infection in acute pyogenic osteomyelitis?

<p>Periosteum (A)</p> Signup and view all the answers

What indicates the existence of a subperiosteal abscess during the later stages of the disease?

<p>Blocked blood supply (A)</p> Signup and view all the answers

What are common clinical features of acute pyogenic osteomyelitis?

<p>Marked-to-intense pain over the affected area (C)</p> Signup and view all the answers

Which of the following is NOT a complication of acute pyogenic osteomyelitis?

<p>Formation of a sequestrum (B)</p> Signup and view all the answers

Which of the following structures is indicative of chronic osteomyelitis?

<p>Cloaca for pus drainage (A)</p> Signup and view all the answers

What is the significance of involucrum in chronic osteomyelitis?

<p>It is the new bone formation surrounding an abscess (D)</p> Signup and view all the answers

What is a common radiographic finding of acute pyogenic osteomyelitis?

<p>Lytic focus of bone destruction (A)</p> Signup and view all the answers

What is the primary cause of pyogenic osteomyelitis?

<p>Bacterial infections (C)</p> Signup and view all the answers

Which organism is responsible for the majority of pyogenic osteomyelitis cases?

<p><em>Staph. aureus</em> (B)</p> Signup and view all the answers

Which method is the most common route for microorganisms to reach the bone?

<p>Hematogenous spread (A)</p> Signup and view all the answers

What type of osteomyelitis is characterized by the duration of disease and can be acute, subacute, or chronic?

<p>Pyogenic osteomyelitis (C)</p> Signup and view all the answers

In neonates, which of the following bacteria is often implicated in causing osteomyelitis?

<p>Group B streptococci (A), <em>H. influenzae</em> (D)</p> Signup and view all the answers

What is one of the potential causes of osteomyelitis in patients with sickle cell disease?

<p><em>Salmonella</em> (C)</p> Signup and view all the answers

Which route for microorganisms to reach the bone involves penetrating injuries and surgical contamination?

<p>Direct implantation (B)</p> Signup and view all the answers

What type of microorganisms are most commonly responsible for osteomyelitis?

<p>Bacteria and mycobacteria (B)</p> Signup and view all the answers

What term best describes the inflammation of bone and marrow secondary to infection?

<p>Osteomyelitis (A)</p> Signup and view all the answers

Which of the following is NOT a recognized method for microorganisms to reach the bone?

<p>Contagious spread (C)</p> Signup and view all the answers

Flashcards

Chronic Osteomyelitis

A prolonged infection of bone, associated with potential complications.

Pathologic fracture

A fracture caused by weakening of bone due to disease or infection.

Brodie's Abscess

A subacute form of osteomyelitis, usually in a long bone's metaphysis.

Metaphysis

The area of a long bone between the epiphysis and the diaphysis.

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Sepsis

A life-threatening condition caused by the body's response to an infection.

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Intracortical Abscess

An abscess located within the bone's cortex.

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Radiopacity

An area of increased radiographic density, appears white on X-ray.

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Secondary Amyloidosis

Amyloid buildup caused by a chronic inflammatory condition.

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Acute Pyogenic Osteomyelitis

An infection of the bone that often affects children and adolescents.

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Metaphysis

The part of a long bone between the diaphysis and epiphysis.

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Epiphysis

The end of a long bone.

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Bone Necrosis

Death of bone tissue due to lack of blood supply.

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Subperiosteal Abscess

Collection of pus under the periosteum.

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Sequestrums

Necrotic bone fragments.

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Involucrum

New bone that forms around an infection.

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Inflammation (Osteomyelitis Stage 1)

Bone ischemia and necrosis within the first 48 hours of infection.

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Suppuration (Osteomyelitis stage 2)

Formation of pus, often leading to a subperiosteal abscess and possible sinus formation.

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Blood Supply Limitation (Osteomyelitis Stage 3)

Reduced blood flow to the bone, leading to necrosis and formation of sequestrum.

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Acute Osteomyelitis Pain

Severe pain localized to the affected bone region, accompanied by systemic symptoms.

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Chronic Osteomyelitis - Sequestrum

Dead bone tissue, often found within an abscess cavity in chronic osteomyelitis.

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Chronic Osteomyelitis - Involucrum

New, thick bony shell developed around chronic infection area.

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Acute Osteomyelitis Complications

Acute osteomyelitis can spread directly (arthritis, myositis) or through the blood (toxemia, septicemia).

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Chronic Osteomyelitis - Cloaca

A draining channel or sinus tract that allows pus to exit the bone in chronic osteomyelitis.

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Osteomyelitis

Inflammation of bone and marrow, usually due to infection.

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Pyogenic Osteomyelitis

Bone inflammation caused by bacteria.

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Common Cause of Pyogenic OM

Staphylococcus aureus (80-90% cases).

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Hematogenous Spread

Most common way bacteria reach bone in osteomyelitis.

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Direct Implantation OM

Bacteria enter the bone through wounds or surgery.

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Contiguous Site OM

Bacteria spread from nearby infections.

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Acute Osteomyelitis

Short-term bone inflammation.

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Subacute Osteomyelitis

Intermediate duration bone inflammation.

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Chronic Osteomyelitis

Long-term bone inflammation.

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Bacteria in Neonates (OM)

H. influenzae and group B Streptococcus often cause OM in newborns.

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Study Notes

Pyogenic Osteomyelitis

  • Acute osteomyelitis is inflammation of bone and bone marrow, almost always due to infection.
  • It's common in children and adolescents, often involving the metaphysis of long bones. In adults, the epiphysis and subchondral regions are more often affected.
  • The disease process involves five stages:
    • Inflammation: includes bone ischemia and necrosis within 48 hours.
    • Suppuration: characterized by a subperiosteal abscess. Pus can reach the skin surface to form a sinus.
    • Blood supply limitation results in bone necrosis, or "Sequestrum," which is separated by the action of osteoclasts.
    • Involucrum: this is new bone formation that encases the inflammatory focus.
    • Resolution or progression to complications.

Chronic Osteomyelitis

  • Definition: Chronic osteomyelitis is a progressive inflammatory process due to incompletely healed or persistent suppurative acute infection.
  • Characterized by:
    • Sequestrum (dead bone) floating inside abscess cavity
    • Involucrum (new bone formation in the wall of abscess)
    • Cloaca: a cortical defect/sinus tract draining pus to the surrounding soft tissues.

Complications of Pyogenic Osteomyelitis

  • Pathologic fracture
  • Secondary amyloidosis
  • Endocarditis
  • Sepsis
  • Squamous cell carcinoma in draining sinus tract

Brodie's Abscess

  • Brodie's abscess is a subacute form of osteomyelitis.
  • It is typically located in the metaphysis of a long bone.
  • It appears as a small intracortical abscess surrounded by reactive bone sclerosis.

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Description

Test your knowledge on the stages and characteristics of pyogenic osteomyelitis, encompassing both acute and chronic forms. This quiz covers the inflammation, suppuration, and healing processes involved in this bone infection commonly affecting children and adults. Explore critical concepts and clinical implications.

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