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Put your DNA Repair Knowledge to the Test
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Put your DNA Repair Knowledge to the Test

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Questions and Answers

What is the consequence of cytosine deamination in DNA?

  • Formation of uracil (correct)
  • Formation of thymine
  • Formation of adenine
  • Formation of guanine

    • Which enzyme removes uracil created by spontaneous deamination of cytosine in DNA?

  • Exonuclease
  • DNA polymerase I
  • Endonuclease
  • Uracil DNA glycolase (correct)

    • What is the role of endonuclease in base excision repair?

  • Cuts the backbone near the defect (correct)
  • Fills in the defect
  • Rejoins the strand
  • Removes the uracil base

    • Which exonuclease removes a few bases in base excision repair?

    <p>5'-3' exonuclease of polymerase I</p> Signup and view all the answers

    Which enzyme fills in the defect in base excision repair?

    <p>DNA polymerase I</p> Signup and view all the answers

    What is the function of ligase in base excision repair?

    <p>Rejoins the strand</p> Signup and view all the answers

    Which amino group is converted into keto group in deamination?

    <p>Cytosine</p> Signup and view all the answers

    Which base is formed as a consequence of cytosine deamination in DNA?

    <p>Uracil</p> Signup and view all the answers

    Which enzyme removes a few bases in nucleotide excision repair?

    <p>Exonuclease</p> Signup and view all the answers

    Which type of repair corrects the altered base derived from deamination?

    <p>Base excision repair</p> Signup and view all the answers

    What is the consequence of cytosine deamination in DNA?

    <p>Formation of uracil</p> Signup and view all the answers

    Which enzyme removes uracil created by spontaneous deamination of cytosine in DNA?

    <p>Uracil DNA glycolase</p> Signup and view all the answers

    What is the role of endonuclease in base excision repair?

    <p>Cuts the backbone near the defect</p> Signup and view all the answers

    Which exonuclease removes a few bases in base excision repair?

    <p>5'-3' exonuclease of polymerase I</p> Signup and view all the answers

    Which enzyme fills in the defect in base excision repair?

    <p>DNA polymerase I</p> Signup and view all the answers

    What is the function of ligase in base excision repair?

    <p>Rejoins the strand</p> Signup and view all the answers

    Which amino group is converted into keto group in deamination?

    <p>Cytosine</p> Signup and view all the answers

    Which base is formed as a consequence of cytosine deamination in DNA?

    <p>Uracil</p> Signup and view all the answers

    Which enzyme removes a few bases in nucleotide excision repair?

    <p>Exonuclease</p> Signup and view all the answers

    Which type of repair corrects the altered base derived from deamination?

    <p>Base excision repair</p> Signup and view all the answers

    What is the name of the enzyme that removes uracil created by spontaneous deamination of cytosine in DNA?

    <p>Uracil DNA glycolase</p> Signup and view all the answers

    What is the result of cytosine deamination?

    <p>Uracil</p> Signup and view all the answers

    What is the function of the endonuclease in base excision repair?

    <p>Cuts the backbone near the defect</p> Signup and view all the answers

    Which exonuclease is responsible for removing a few bases in base excision repair?

    <p>5'-3' of polymerase I</p> Signup and view all the answers

    What is the final step in base excision repair?

    <p>Rejoining the strand</p> Signup and view all the answers

    What is the result of deamination of guanine?

    <p>Xanthine</p> Signup and view all the answers

    Which enzyme is responsible for filling in the defect in base excision repair?

    <p>DNA polymerase I</p> Signup and view all the answers

    What is the role of ligase in base excision repair?

    <p>Rejoins the strand</p> Signup and view all the answers

    What is the result of deamination of adenine?

    <p>Cytosine</p> Signup and view all the answers

    Which type of repair corrects the altered base derived from deamination in DNA?

    <p>Base excision repair</p> Signup and view all the answers

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