Put your DNA Repair Knowledge to the Test
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Questions and Answers

What is the consequence of cytosine deamination in DNA?

  • Formation of uracil (correct)
  • Formation of thymine
  • Formation of adenine
  • Formation of guanine

Which enzyme removes uracil created by spontaneous deamination of cytosine in DNA?

  • Exonuclease
  • DNA polymerase I
  • Endonuclease
  • Uracil DNA glycolase (correct)

What is the role of endonuclease in base excision repair?

  • Cuts the backbone near the defect (correct)
  • Fills in the defect
  • Rejoins the strand
  • Removes the uracil base

Which exonuclease removes a few bases in base excision repair?

<p>5'-3' exonuclease of polymerase I (A)</p> Signup and view all the answers

Which enzyme fills in the defect in base excision repair?

<p>DNA polymerase I (D)</p> Signup and view all the answers

What is the function of ligase in base excision repair?

<p>Rejoins the strand (D)</p> Signup and view all the answers

Which amino group is converted into keto group in deamination?

<p>Cytosine (D)</p> Signup and view all the answers

Which base is formed as a consequence of cytosine deamination in DNA?

<p>Uracil (B)</p> Signup and view all the answers

Which enzyme removes a few bases in nucleotide excision repair?

<p>Exonuclease (A)</p> Signup and view all the answers

Which type of repair corrects the altered base derived from deamination?

<p>Base excision repair (B)</p> Signup and view all the answers

What is the consequence of cytosine deamination in DNA?

<p>Formation of uracil (C)</p> Signup and view all the answers

Which enzyme removes uracil created by spontaneous deamination of cytosine in DNA?

<p>Uracil DNA glycolase (A)</p> Signup and view all the answers

What is the role of endonuclease in base excision repair?

<p>Cuts the backbone near the defect (D)</p> Signup and view all the answers

Which exonuclease removes a few bases in base excision repair?

<p>5'-3' exonuclease of polymerase I (B)</p> Signup and view all the answers

Which enzyme fills in the defect in base excision repair?

<p>DNA polymerase I (B)</p> Signup and view all the answers

What is the function of ligase in base excision repair?

<p>Rejoins the strand (B)</p> Signup and view all the answers

Which amino group is converted into keto group in deamination?

<p>Cytosine (D)</p> Signup and view all the answers

Which base is formed as a consequence of cytosine deamination in DNA?

<p>Uracil (A)</p> Signup and view all the answers

Which enzyme removes a few bases in nucleotide excision repair?

<p>Exonuclease (B)</p> Signup and view all the answers

Which type of repair corrects the altered base derived from deamination?

<p>Base excision repair (A)</p> Signup and view all the answers

What is the name of the enzyme that removes uracil created by spontaneous deamination of cytosine in DNA?

<p>Uracil DNA glycolase (D)</p> Signup and view all the answers

What is the result of cytosine deamination?

<p>Uracil (B)</p> Signup and view all the answers

What is the function of the endonuclease in base excision repair?

<p>Cuts the backbone near the defect (B)</p> Signup and view all the answers

Which exonuclease is responsible for removing a few bases in base excision repair?

<p>5'-3' of polymerase I (A)</p> Signup and view all the answers

What is the final step in base excision repair?

<p>Rejoining the strand (B)</p> Signup and view all the answers

What is the result of deamination of guanine?

<p>Xanthine (B)</p> Signup and view all the answers

Which enzyme is responsible for filling in the defect in base excision repair?

<p>DNA polymerase I (D)</p> Signup and view all the answers

What is the role of ligase in base excision repair?

<p>Rejoins the strand (A)</p> Signup and view all the answers

What is the result of deamination of adenine?

<p>Cytosine (B)</p> Signup and view all the answers

Which type of repair corrects the altered base derived from deamination in DNA?

<p>Base excision repair (C)</p> Signup and view all the answers

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