Podcast
Questions and Answers
What primarily causes most damage during ARDS?
What primarily causes most damage during ARDS?
- IL-10
- IL-1
- TNFa (correct)
- IL-6
What is a major consequence of decreased presence of surfactants in ARDS?
What is a major consequence of decreased presence of surfactants in ARDS?
- Enhanced lung volume
- Increased alveolar compliance
- Improved gas exchange
- Atelectasis (correct)
Which of the following is a symptom of ARDS?
Which of the following is a symptom of ARDS?
- Formation of hyaline membranes (correct)
- Enhanced type II pneumocyte function
- Decreased fibrosis of alveolar walls
- Increased total lung volume
Which cellular process is involved in the fibrotic response seen in ARDS?
Which cellular process is involved in the fibrotic response seen in ARDS?
What is a direct effect of the liquefaction necrosis seen in ARDS?
What is a direct effect of the liquefaction necrosis seen in ARDS?
What is the primarily reduced measurement in cases of emphysema, pneumonia, and pulmonary edema when assessing lung function?
What is the primarily reduced measurement in cases of emphysema, pneumonia, and pulmonary edema when assessing lung function?
Which component contributes to the calculation of Functional Residual Capacity (FRC)?
Which component contributes to the calculation of Functional Residual Capacity (FRC)?
Which pulmonary capacity is defined as the maximum amount of air expirable after the lungs are filled to maximum extent?
Which pulmonary capacity is defined as the maximum amount of air expirable after the lungs are filled to maximum extent?
What happens to the Total Lung Capacity (TLC) in restrictive disorders?
What happens to the Total Lung Capacity (TLC) in restrictive disorders?
What is the average Vital Capacity (VC) for women?
What is the average Vital Capacity (VC) for women?
Which of the following processes is NOT involved in pulmonary function?
Which of the following processes is NOT involved in pulmonary function?
When is Functional Residual Capacity (FRC) typically increased?
When is Functional Residual Capacity (FRC) typically increased?
Which measurement indicates both respiratory muscle strength and ventilatory reserve?
Which measurement indicates both respiratory muscle strength and ventilatory reserve?
What is the role of ventilation in the respiratory system?
What is the role of ventilation in the respiratory system?
Why is it easier for foreign objects to be aspirated into the right bronchus?
Why is it easier for foreign objects to be aspirated into the right bronchus?
What primarily affects airway resistance in the respiratory system?
What primarily affects airway resistance in the respiratory system?
According to Boyle's Law, how does the volume of gas change in relation to pressure?
According to Boyle's Law, how does the volume of gas change in relation to pressure?
What is an example of an anatomic dead space in the respiratory system?
What is an example of an anatomic dead space in the respiratory system?
What is the primary purpose of goblet cells in the respiratory system?
What is the primary purpose of goblet cells in the respiratory system?
What occurs during inhalation according to the principles of pressure in the lungs?
What occurs during inhalation according to the principles of pressure in the lungs?
What defines physiologic dead space in the respiratory system?
What defines physiologic dead space in the respiratory system?
What is the primary purpose of bile in digestion?
What is the primary purpose of bile in digestion?
Which type of carcinoma is generally considered more responsive to treatment?
Which type of carcinoma is generally considered more responsive to treatment?
What is a characteristic feature of malignant cells?
What is a characteristic feature of malignant cells?
Which cells secrete bile acids and other components into bile canaliculi?
Which cells secrete bile acids and other components into bile canaliculi?
What environmental factor is responsible for 85% of all lung cancer deaths?
What environmental factor is responsible for 85% of all lung cancer deaths?
How does the gallbladder contribute to bile concentration?
How does the gallbladder contribute to bile concentration?
Which symptom is NOT commonly associated with lung cancer?
Which symptom is NOT commonly associated with lung cancer?
What stimulates gallbladder emptying after a meal?
What stimulates gallbladder emptying after a meal?
Which enzyme is primarily involved in the digestion of fats?
Which enzyme is primarily involved in the digestion of fats?
Which is a known carcinogen that can contribute to lung cancer development?
Which is a known carcinogen that can contribute to lung cancer development?
What is the primary function of the gastrointestinal (GI) tract?
What is the primary function of the gastrointestinal (GI) tract?
What factor can lead to the development of gallstones?
What factor can lead to the development of gallstones?
What is indicated by a high level of environmental carcinogens in an individual?
What is indicated by a high level of environmental carcinogens in an individual?
Which structure is not involved in the secretion of bile?
Which structure is not involved in the secretion of bile?
What defines the process of malignant transformation in cells?
What defines the process of malignant transformation in cells?
What effect do enterogastric reflexes have on stomach emptying?
What effect do enterogastric reflexes have on stomach emptying?
What primarily initiates the inhibition of the pyloric pump contractions?
What primarily initiates the inhibition of the pyloric pump contractions?
Which process moves chyme through the digestive tract at a very slow pace?
Which process moves chyme through the digestive tract at a very slow pace?
What is the primary role of Brunner's glands located in the duodenum?
What is the primary role of Brunner's glands located in the duodenum?
Which statement correctly describes the action of segmentation in the small intestine?
Which statement correctly describes the action of segmentation in the small intestine?
What is the main consequence of sympathetic stimulation on Brunner's glands?
What is the main consequence of sympathetic stimulation on Brunner's glands?
What role do goblet cells play in the intestinal lining?
What role do goblet cells play in the intestinal lining?
How long does it take for chyme to travel from the pylorus to the ileocecal valve?
How long does it take for chyme to travel from the pylorus to the ileocecal valve?
Which of the following factors does NOT lead to the secretion of secretin from the duodenum?
Which of the following factors does NOT lead to the secretion of secretin from the duodenum?
Flashcards
DLCO (Diffusing Capacity of Lung Carbon Monoxide)
DLCO (Diffusing Capacity of Lung Carbon Monoxide)
Measures how well gas moves from alveoli to erythrocytes in pulmonary circulation.
Inspiratory Capacity (IC)
Inspiratory Capacity (IC)
Maximum air inspired, combining tidal volume and inspiratory reserve volume.
Functional Residual Capacity (FRC)
Functional Residual Capacity (FRC)
Air remaining in lungs after normal exhalation, comprising expiratory reserve volume and residual volume.
Vital Capacity (VC)
Vital Capacity (VC)
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Total Lung Capacity (TLC)
Total Lung Capacity (TLC)
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Forced Vital Capacity (FVC)
Forced Vital Capacity (FVC)
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Obstructive Pulmonary Disorders
Obstructive Pulmonary Disorders
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Restrictive Pulmonary Disorders
Restrictive Pulmonary Disorders
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ARDS Definition
ARDS Definition
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ARDS Cause
ARDS Cause
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ARDS Inflammation
ARDS Inflammation
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ARDS Tissue Damage
ARDS Tissue Damage
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Hyaline Membranes ARDS
Hyaline Membranes ARDS
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ARDS Surfactants
ARDS Surfactants
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ARDS Fibrosis
ARDS Fibrosis
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ARDS Alveolar Volume
ARDS Alveolar Volume
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ARDS Atelectasis
ARDS Atelectasis
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Pancreatic Lipase
Pancreatic Lipase
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Centeroacinar Cells
Centeroacinar Cells
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Bile Purpose
Bile Purpose
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Bile Secretion
Bile Secretion
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Gallbladder Function
Gallbladder Function
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Gallstones
Gallstones
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Stomach Emptying Regulation
Stomach Emptying Regulation
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Non-small cell lung cancer
Non-small cell lung cancer
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Adenocarcinoma lung cancer
Adenocarcinoma lung cancer
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Squamous cell carcinoma (lung)
Squamous cell carcinoma (lung)
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Large cell carcinoma (lung)
Large cell carcinoma (lung)
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Small cell lung cancer
Small cell lung cancer
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Malignant transformation
Malignant transformation
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Environmental carcinogens
Environmental carcinogens
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Cigarette smoking (lung cancer)
Cigarette smoking (lung cancer)
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GI tract
GI tract
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Alimentary canal
Alimentary canal
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Digestion and absorption
Digestion and absorption
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Ventilation
Ventilation
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Perfusion
Perfusion
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Gas Diffusion
Gas Diffusion
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Right Bronchus
Right Bronchus
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Alveoli
Alveoli
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Dead Space
Dead Space
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Anatomic Dead Space
Anatomic Dead Space
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Physiologic Dead Space
Physiologic Dead Space
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Airway Resistance
Airway Resistance
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Boyle's Law
Boyle's Law
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Inhalation
Inhalation
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Exhalation
Exhalation
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Duodenal Distension
Duodenal Distension
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Irritated Duodenal Mucosa
Irritated Duodenal Mucosa
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Pyloric Pump
Pyloric Pump
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Pyloric Sphincter
Pyloric Sphincter
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Ileocecal Valve
Ileocecal Valve
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Mixing Contractions/Segmentation
Mixing Contractions/Segmentation
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Peristalsis
Peristalsis
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Brunner's Glands
Brunner's Glands
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Goblet Cells
Goblet Cells
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Enterocytes
Enterocytes
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Study Notes
Pulmonary Volumes
- Tidal Volume (TV): Volume of air inhaled and exhaled in a normal breath, approximately 500 mL.
- Minute Tidal Volume: Total volume of air inhaled and exhaled per minute (TV x respiratory rate), approximately 8 L.
- Alveolar Volume: Volume of air reaching the alveoli (Tidal Volume – dead space volume), approximately 350 mL. Average minute alveolar volume is 5600 mL.
- Inspiratory Reserve Volume (IRV): Extra volume of air that can be inhaled beyond a normal breath, approximately 3000 mL. Indicates inspiratory muscle strength.
- Expiratory Reserve Volume (ERV): Volume of air that can be forcefully exhaled after a normal breath, approximately 1100 mL. Indicates expiratory muscle strength.
- Residual Volume (RV): Volume of air remaining in lungs after a forceful exhalation, approximately 1200 mL. Indicates airway patency & elasticity.
Pulmonary Capacities
- Inspiratory Capacity (IC): Maximum amount of air that can be inspired (TV + IRV), approximately 3500 mL.
- Functional Residual Capacity (FRC): Amount of air remaining in the lungs at the end of a normal breath (ERV + RV), approximately 2300 mL. Increased in obstructive disorders.
- Vital Capacity (VC): Maximum amount of air that can be expelled from the lungs after maximum inhalation (IRV + TV + ERV), approximately 4600 mL.
- Total Lung Capacity (TLC): Maximum volume lungs can hold (TV + IRV + ERV + RV), approximately 6 L. Reduced in restrictive disorders, increased in severe COPD.
- Forced Vital Capacity (FVC): Maximum amount of air that can be exhaled as quickly as possible, indicates respiratory muscle strength and ventilatory reserve. Average for men is 4800 mL, women is 3500 mL. Reduced in obstructive and restrictive diseases.
Pulmonary Functions
- Ventilation: Movement of air into and out of the lungs.
- Perfusion: Circulation of blood through the lungs.
- Diffusion: Movement of oxygen and carbon dioxide across the alveolocapillary membrane.
- Regulation of oxygenation and gas exchange
- Protection (macrophages, surfactant)
- Maintenance of cardiac output and blood pressure
- Immunity
- Fluid, electrolyte, and acid-base balance
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