Pulmonary Infections and Immune Deficiencies

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29 Questions

Which factor increases the risk for pneumonias caused by encapsulated organisms such as pneumococcus and H.influenzae?

Defects in TH1 cell–mediated immunity

In which clinical settings is Streptococcus pneumoniae seen with increased frequency?

Chronic diseases such as CHF, COPD, or diabetes

What increases the risk for a particularly life-threatening form of pneumonia in children, often after a respiratory viral infection?

Encapsulated forms of Haemophilus influenzae

What is compromised by alcohol, increasing the risk for aspiration?

Cough and epiglottic reflexes

What is a part of the endogenous flora in 20% of adults?

S. pneumoniae

What is used in individuals at high risk for pneumococcal sepsis?

Pneumococcal vaccines containing capsular polysaccharides

What is a common clinical presentation of Blastomycosis?

Pneumonia with pink-staining exudate

How is Cytomegalovirus (CMV) primarily transmitted to preschool children?

Through saliva

Which organism is responsible for causing interstitial pneumonitis with 'cotton candy' exudate in the lungs?

Pneumocystis P. jiroveci

What is the classic form of symptomatic disease that occurs in neonates infected with Cytomegalovirus (CMV)?

'Owl's eye' inclusion surrounded by a clear halo

What is the most likely clinical manifestation of Cryptococcus infection in immunocompromised hosts?

Pulmonary, central nervous system, or disseminated disease

Which organism causes a disease characterized by a thick, gelatinous capsule and reproduces by budding?

Cryptococcus neoformans

'Cotton candy' exudate in the lungs is a characteristic feature of which infection?

Pneumocystis P. jiroveci infection

Which opportunistic infection is likely to result in renal abscess and endophthalmitis?

Candidiasis

'Rhinocerebral' and 'pulmonary' are common manifestations of which opportunistic mold infection?

Mucormycosis

In immunocompromised individuals, what is a characteristic feature of Candida albicans when visualized under special 'fungal' stains?

Blastoconidia and pseudohyphae

How does Pneumocystis P. jiroveci primarily manifest in immunocompromised individuals?

Interstitial pneumonitis with 'cotton candy' exudate

Which organism exhibits gigantism of both the cytoplasm and the nucleus when infected by the virus?

Cytomegalovirus

Which bacterium is the most common cause of acute exacerbations of COPD?

Moraxella catarrhalis

What is the most common bacterial cause of otitis media in children?

H. influenzae

Which bacterium is an important cause of nosocomial pneumonia and is commonly associated with infections in cystic fibrosis?

Pseudomonas aeruginosa

What is the most frequent cause of gram-negative bacterial pneumonia and is characteristic of debilitated and malnourished individuals, particularly chronic alcoholics?

Klebsiella pneumoniae

Which bacterium has a propensity to invade blood vessels at the site of infection and is associated with a high incidence of complications such as lung abscess and empyema?

Pseudomonas aeruginosa

Which bacterium is the most common cause of secondary bacterial pneumonia in children and healthy adults after viral respiratory illnesses?

Staphylococcus aureus

Which bacterium is the most common bacterial cause of acute exacerbations of COPD in adults?

Moraxella catarrhalis

What bacterium is associated with infections in cystic fibrosis and is commonly seen in nosocomial settings?

Pseudomonas aeruginosa

Which bacterium has a propensity to invade blood vessels at the site of infection and is associated with a high incidence of complications?

Pseudomonas aeruginosa

Which bacterium is the most common cause of otitis media in children?

H. influenzae

What bacterium is an important cause of nosocomial pneumonia and is commonly associated with infections in cystic fibrosis?

Pseudomonas aeruginosa

Test your knowledge about pulmonary infections and immune deficiencies related to mutations in MYD88, congenital defects in IgA production, compromised immunity, and environmental factors such as cigarette smoke and alcohol.

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