Pulmonary Hypertension Quiz
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Questions and Answers

What is the female/male ratio for pulmonary hypertension?

  • 2 to 1
  • 1.8 to 1 (correct)
  • 3 to 1
  • 1 to 1
  • Which group of WHO hypertension classification does pulmonary arterial hypertension (PAH) belong to?

  • Group 2
  • Group 4
  • Group 3
  • Group 1 (correct)
  • What is the mechanism behind the increased pulmonary vascular resistance in pulmonary hypertension?

  • Chronic inflammation
  • Vascular remodeling (correct)
  • Endothelial proliferation
  • Decreased vasodilators
  • Which subgroups of pulmonary arterial hypertension (PAH) are mentioned in the text?

    <p>Idiopathic PAH, Heritable PAH, Drug/toxin induced PAH</p> Signup and view all the answers

    What happens in Group 2 pulmonary hypertension (PH) according to the text?

    <p>Blood backs up in lungs, causing congestion and increased pulmonary pressure</p> Signup and view all the answers

    What is the initial screening test for pulmonary hypertension mentioned in the text?

    <p>Echo</p> Signup and view all the answers

    What ECG finding may be present in some patients with pulmonary hypertension?

    <p>Incomplete or complete R bundle branch block</p> Signup and view all the answers

    What does the 6 minute walk test measure?

    <p>Marker for physical function, Measures meters walked</p> Signup and view all the answers

    What does Group 5 PH involve?

    <p>PH from unclear/multifactorial mechanisms</p> Signup and view all the answers

    What is the estimated systolic pulmonary artery pressure considered elevated in adults?

    <p>Greater than 30 mmHg</p> Signup and view all the answers

    What happens in Group 3 pulmonary hypertension (PH) according to the text?

    <p>PH from chronic lung disease and/or hypoxia</p> Signup and view all the answers

    What is the main cause of increased pulmonary vascular resistance (PVR) in Group 4 PH?

    <p>Obstructive vasculopathy of arterioles</p> Signup and view all the answers

    Which one of the following is more commonly associated with PAH?

    <p>Pulmonary hypertension from chronic lung diseases or hypoxia</p> Signup and view all the answers

    Which of the following is a characteristic feature of R hypertensive heart disease?

    <p>Pulmonary artery to ascending aorta diameter ratio &lt; 1</p> Signup and view all the answers

    What is a pathologic finding of R heart failure?

    <p>Cardiac sclerosis of the liver</p> Signup and view all the answers

    Which stage of PH (by WHO) is characterized by symptoms at rest and signs suggestive of R-sided congestive heart failure?

    <p>Class IV</p> Signup and view all the answers

    What is the characteristic functional activity limitation in Class II stage of PH (by WHO)?

    <p>Comfortable at rest but has slight limitations with activity</p> Signup and view all the answers

    What is the characteristic functional activity limitation in Class III stage of PH (by WHO)?

    <p>Comfortable at rest but has significant limitations with activity</p> Signup and view all the answers

    What is the characteristic functional activity limitation in Class I stage of PH (by WHO)?

    <p>No limitation with functional activity</p> Signup and view all the answers

    What is the characteristic functional activity limitation in Class IV stage of PH (by WHO)?

    <p>Symptoms at rest</p> Signup and view all the answers

    Which of the following is a pathologic finding of R heart failure?

    <p>Cardiac sclerosis of the liver</p> Signup and view all the answers

    What is the characteristic pathologic finding in cor pulmonale?

    <p>Cardiac sclerosis of the liver</p> Signup and view all the answers

    What is the characteristic pressure overload in cor pulmonale?

    <p>Pressure overload in RV due to pulmonary HTN</p> Signup and view all the answers

    Study Notes

    Pulmonary Hypertension

    • The female to male ratio for pulmonary hypertension is 2.5:1.

    WHO Classification of Pulmonary Hypertension

    • Pulmonary arterial hypertension (PAH) belongs to Group 1.

    Mechanism of Pulmonary Hypertension

    • Increased pulmonary vascular resistance in pulmonary hypertension is caused by vasoconstriction, proliferation of vascular smooth muscle cells, and inflammation.

    Subgroups of Pulmonary Arterial Hypertension (PAH)

    • The subgroups of PAH mentioned are: idiopathic, heritable, drug- and toxin-induced, associated with connective tissue diseases, HIV infection, portal hypertension, and congenital heart diseases.

    Group 2 Pulmonary Hypertension (PH)

    • In Group 2 PH, the left heart disease leads to an increase in pulmonary venous pressure.

    Screening Test for Pulmonary Hypertension

    • The initial screening test for pulmonary hypertension is an echocardiogram.

    ECG Findings in Pulmonary Hypertension

    • A right axis deviation may be present in some patients with pulmonary hypertension.

    6-Minute Walk Test

    • The 6-minute walk test measures the exercise capacity and functional class of patients with pulmonary hypertension.

    Group 5 Pulmonary Hypertension (PH)

    • Group 5 PH involves multifactorial mechanisms, including hematological disorders, systemic disorders, and miscellaneous conditions.

    Systolic Pulmonary Artery Pressure

    • An estimated systolic pulmonary artery pressure of >40 mmHg is considered elevated in adults.

    Group 3 Pulmonary Hypertension (PH)

    • In Group 3 PH, the chronic lung disease leads to hypoxemia and vasoconstriction.

    Group 4 Pulmonary Hypertension (PH)

    • The main cause of increased pulmonary vascular resistance in Group 4 PH is chronic thrombotic or embolic disease.

    Association with PAH

    • Connective tissue diseases are more commonly associated with PAH.

    Right Ventricular Hypertensive Heart Disease

    • Right ventricular hypertrophy is a characteristic feature of R hypertensive heart disease.

    Pathologic Findings of R Heart Failure

    • A pathologic finding of R heart failure is right ventricular hypertrophy.

    WHO Classification of PH

    • Stage IV of PH is characterized by symptoms at rest and signs suggestive of R-sided congestive heart failure.

    Functional Activity Limitations in PH

    • In Class I, patients have no limitation of physical activity.
    • In Class II, patients have slight limitation of physical activity.
    • In Class III, patients have marked limitation of physical activity.
    • In Class IV, patients are unable to carry out any physical activity without symptoms.

    Cor Pulmonale

    • The characteristic pathologic finding in cor pulmonale is right ventricular hypertrophy and dilation.
    • The characteristic pressure overload in cor pulmonale is right ventricular pressure overload.

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    Description

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