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Questions and Answers
What is the first-line eradication therapy for H. pylori?
What is the first-line eradication therapy for H. pylori?
- Amoxicillin, clarithromycin/metronidazole, and a PPI (correct)
- Proton pump inhibitors, H2-receptor antagonists, antacids, prostaglandin analogs, and mucosal barrier fortifiers
- Different antibiotics and an extended course
- None of the above
When is surgical treatment for PUD indicated?
When is surgical treatment for PUD indicated?
- None of the above
- When there is a low level of gastric secretion
- As a first-line treatment
- When medical treatment fails, complications develop, or there is a high level of gastric secretion (correct)
What is the principle of surgical treatment for PUD?
What is the principle of surgical treatment for PUD?
- To eliminate H. pylori bacteria
- To reduce acid and pepsin secretion (correct)
- To increase acid and pepsin secretion
- To prevent the development of complications
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Study Notes
- PUD management involves non-pharmacologic and pharmacologic therapies.
- Non-pharmacologic therapies include lifestyle modification and surgery.
- Pharmacologic therapies include hypo-secretory drug therapy and H. pylori eradication therapy.
- Hypo-secretory drug therapy involves proton pump inhibitors, H2-receptor antagonists, antacids, prostaglandin analogs, and mucosal barrier fortifiers.
- H. pylori eradication therapy involves a 7-day course of triple-therapy with a PPI and dual antibiotic therapy.
- First-line eradication therapy uses amoxicillin, clarithromycin/metronidazole, and a PPI.
- Second-line eradication therapy uses different antibiotics and an extended course.
- Patient allergy and previous antibiotic exposure are taken into account for H. pylori eradication therapy.
- Indications for surgical treatment include failure of medical treatment, development of complications, and high level of gastric secretion.
- The principle of surgical treatment is to reduce acid and pepsin secretion.
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