Psychopharmacology Quiz
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Questions and Answers

What is the mechanism of action of Sodium Valproate?

  • Stimulating the release of neurotransmitters
  • Decreasing synaptic transmission (correct)
  • Blocking the action of neurotransmitters
  • Increasing synaptic transmission
  • What is the classification of Sodium Valproate?

  • Antidepressant
  • Antianxiety drug
  • Mood Stabilizing (correct)
  • Benzodiazepine
  • What is the usual dose of Sodium Valproate?

  • 15mg/kg/ day (correct)
  • 25mg/kg/ day
  • 10mg/kg/ day
  • 20mg/kg/ day
  • What is a common adverse effect of Sodium Valproate?

    <p>Nausea</p> Signup and view all the answers

    What is the nurse's responsibility in administering Sodium Valproate?

    <p>Monitor liver function test</p> Signup and view all the answers

    What should the client be taught to do if they experience a painful rash, hives, blisters, or fever?

    <p>Call the physician immediately</p> Signup and view all the answers

    What type of antidepressant is DuloxeTINE?

    <p>Atypical Antidepressants</p> Signup and view all the answers

    What is a side effect of Tricyclic Antidepressants (TCA)?

    <p>Urinary retention</p> Signup and view all the answers

    Which receptor may be targeted by future drugs with dual antipsychotic and antidepressant therapeutic potential?

    <p>Adenosine-2A (A2A) receptor</p> Signup and view all the answers

    What is a nursing responsibility when patients are taking MAOIs?

    <p>Warning against tyramine-rich foods</p> Signup and view all the answers

    What is an indication for antidepressant therapy?

    <p>Depressive episode</p> Signup and view all the answers

    What is a cardiac side-effect of antidepressants?

    <p>Tachycardia</p> Signup and view all the answers

    What is the therapeutic level of Lithium in the treatment of acute mania?

    <p>0.8 - 1.2 mEq/L</p> Signup and view all the answers

    What is a common side effect of Lithium on the cardiovascular system?

    <p>T-wave depression</p> Signup and view all the answers

    What is the recommended dosage of Lithium per day in acute mania?

    <p>900-1200mg</p> Signup and view all the answers

    What is a dermatological side effect of Lithium?

    <p>All of the above</p> Signup and view all the answers

    What is an indication for Lithium treatment?

    <p>Acute mania</p> Signup and view all the answers

    What should the patient be cautioned about when taking Lithium?

    <p>To change his position slowly</p> Signup and view all the answers

    Study Notes

    Mood Stabilizing Drugs

    • Foods that interact with mood stabilizing drugs include beef liver, chicken liver, dried fish, overripe fruits, chocolate, wine, beer, and coffee
    • Changing positions slowly can minimize orthostatic hypotension
    • Lithium is used to treat acute mania, bipolar disorder, and schizoaffective disorder
    • Therapeutic levels of lithium are between 0.8-1.2 mEq/L, and prophylactic levels are between 0.6-1.2 mEq/L

    Adverse Effects of Lithium

    • Neurological: Tremors, motor hyperactivity, muscular weakness, cogwheel rigidity, seizures, delirium, and coma
    • Renal: Polydipsia, polyuria, nephrotic syndrome
    • Cardiovascular: T-wave depression
    • Gastrointestinal: Nausea, vomiting, diarrhea, abdominal pain, and metallic taste
    • Endocrine: Abnormal thyroid function, goiter, and weight gain
    • Dermatological: Acneiform eruptions, popular eruptions, and exacerbation of psoriasis
    • Teratogenic possibility, increased incidence of Ebstein's anomaly during pregnancy and lactation

    Nursing Responsibilities for Lithium

    • Monitor liver function tests for liver damage
    • Monitor BUN and creatinine
    • Monitor CBC and electrolytes (leucopenia)
    • Observe for changes in mental state
    • Observe for allergies
    • Teach client to call the physician if there are signs of Stevens-Johnson syndrome

    Sodium Valproate

    • Dosage is 15mg/kg/day with a maximum of 60mg/kg/day orally
    • Indications include acute mania, prophylactic treatment of bipolar disorder, and schizoaffective disorder
    • Adverse effects include nausea, vomiting, diarrhea, sedation, weight gain, and thrombocytopenia

    Antidepressants

    • Classification includes Monoamine Oxidase Inhibitors (MAOI), Tricyclic Antidepressants (TCA), Selective Serotonin Reuptake Inhibitors (SSRIs), and Atypical Antidepressants
    • Examples of antidepressants include Phenelzine, Imipramine, Fluoxetine, and Duloxetine
    • Indications include depression, depressive episode, dysthymia, and other psychiatric disorders
    • Adverse effects include autonomic side-effects, CNS effects, cardiac side-effects, allergic side-effects, and metabolic and endocrine side-effects

    Nursing Responsibilities for Antidepressants

    • Warn patients on MAOIs about the danger of ingesting tyramine-rich foods, which can result in hypertensive crisis

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    Description

    Test your knowledge of psychopharmacology with this quiz, covering mood stabilizing drugs, treatment adherence, and cautions for specific medications. Learn about lithium dosage and blood levels, as well as interactions with certain foods and substances.

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