Sites of Drug Action

Reserpine

Apomorphine

ACh

<p>Botulinum toxin</p> Signup and view all the answers

<p>Nicotine</p> Signup and view all the answers

<p>Curare</p> Signup and view all the answers

<p>Idazoxan</p> Signup and view all the answers

<p>Cocaine</p> Signup and view all the answers

<p>Physostigmine</p> Signup and view all the answers

<p>Curare</p> Signup and view all the answers

<p>The study of the effects of drugs on the nervous system and behavior</p> Signup and view all the answers

<p>Exogenous chemicals that significantly alter the functions of certain cells of the body</p> Signup and view all the answers

<p>The fate of a drug as it is absorbed into the body, circulates throughout the body, and reaches its sites of action</p> Signup and view all the answers

<p>Intracerebrally</p> Signup and view all the answers

<p>Lipid-soluble drugs</p> Signup and view all the answers

<p>Some are deactivated by enzymes and others are excreted</p> Signup and view all the answers

<p>A drug's effectiveness</p> Signup and view all the answers

<p>Plants and animals that produce chemicals that act on the nervous system</p> Signup and view all the answers

<p>The effects of drugs on the nervous system and behavior</p> Signup and view all the answers

<p>Chemicals that are not necessary for normal cellular functioning</p> Signup and view all the answers

<p>Agonists</p> Signup and view all the answers

<p>They initiate the release of neurotransmitters into the synaptic cleft</p> Signup and view all the answers

<p>All of the above</p> Signup and view all the answers

<p>Agonists facilitate the effects of a neurotransmitter, while antagonists inhibit the effects</p> Signup and view all the answers

<p>The difference between doses that produce desirable effects and toxic side effects</p> Signup and view all the answers

<p>They reuptake neurotransmitters from the synaptic cleft</p> Signup and view all the answers

<p>Agonists and antagonists</p> Signup and view all the answers

<p>Pharmacokinetics of the drugs</p> Signup and view all the answers

<p>They regulate the synthesis and release of neurotransmitters</p> Signup and view all the answers

<p>They destroy neurotransmitters in the synaptic cleft</p> Signup and view all the answers

<p>He had trouble with his vision</p> Signup and view all the answers

<p>He rinsed it under water and threw it away</p> Signup and view all the answers

<p>He was seeing double</p> Signup and view all the answers

<p>A chemical that has a therapeutic effect on a disease or its symptoms</p> Signup and view all the answers

<p>Produced from outside the body</p> Signup and view all the answers

<p>Neurotransmitters</p> Signup and view all the answers

<p>Large quantities of any substance can alter the functions of cells</p> Signup and view all the answers

<p>Indirect antagonist</p> Signup and view all the answers

<p>Decrease the release of neurotransmitter</p> Signup and view all the answers

<p>Inhibit the release of the neurotransmitter</p> Signup and view all the answers

<p>Decrease neural firing</p> Signup and view all the answers

<p>Direct antagonist</p> Signup and view all the answers

<p>Reuptake</p> Signup and view all the answers

<p>Activation of dendritic autoreceptors</p> Signup and view all the answers

<p>Indirect antagonist</p> Signup and view all the answers

<p>They regulate the synthesis and release of neurotransmitters</p> Signup and view all the answers

<p>To investigate the operations of the nervous system</p> Signup and view all the answers

<p>The difference between doses that produce desirable effects and those that produce toxic side effects</p> Signup and view all the answers

<p>Lipid-soluble drugs</p> Signup and view all the answers

<p>Drugs that deactivate the proteins that cause docked synaptic vesicles to fuse with the presynaptic membrane</p> Signup and view all the answers

<p>The ion channels controlled by the receptors open and produce postsynaptic potentials</p> Signup and view all the answers

<p>They prevent the neurotransmitter from opening the ion channel</p> Signup and view all the answers

<p>They pump molecules of the neurotransmitter across the membrane, filling the vesicles</p> Signup and view all the answers

<p>He had difficulty swallowing and his voice became weak.</p> Signup and view all the answers

<p>He rinsed his mouth and tongue with water.</p> Signup and view all the answers

<p>It blocks the receptor and prevents the neurotransmitter from binding.</p> Signup and view all the answers

<p>Stimulating autoreceptors</p> Signup and view all the answers

<p>Antagonists</p> Signup and view all the answers

<p>To block postsynaptic receptors</p> Signup and view all the answers

<p>Inhibition of synthesis/release of neurotransmitters</p> Signup and view all the answers

<p>Exogenous drugs</p> Signup and view all the answers

<p>Antagonists</p> Signup and view all the answers

<p>Agonists</p> Signup and view all the answers

<p>Precursor effect</p> Signup and view all the answers

<p>It occurs when a molecule binds with an alternative site and does not compete with molecules of the neurotransmitter</p> Signup and view all the answers

<p>It facilitates the release of the neurotransmitter</p> Signup and view all the answers

<p>They regulate the amount of neurotransmitter released</p> Signup and view all the answers

<p>They decrease neural firing by producing hyperpolarizations</p> Signup and view all the answers

<p>An exogenous chemical not necessary for normal cellular functioning that significantly alters the functions of certain cells of the body when taken in relatively low doses</p> Signup and view all the answers

<p>Neurotransmitters</p> Signup and view all the answers

<p>To take molecules of the neurotransmitter back into the terminal button</p> Signup and view all the answers

<p>Agonists bind with a receptor and activate it, mimicking the effects of the natural ligand. Antagonists bind with a receptor but do not activate it, preventing the natural ligand from binding with the receptor.</p> Signup and view all the answers

<p>A drug that inactivates the enzyme that normally destroys acetylcholine</p> Signup and view all the answers

<p>A drug that prevents the storage of neurotransmitter in synaptic vesicles</p> Signup and view all the answers

<p>A drug that stimulates the release of neurotransmitter</p> Signup and view all the answers

<p>A drug that blocks the reuptake of neurotransmitters</p> Signup and view all the answers